(14 nodes) Regulation of cell proliferation involved in heart morphogenesis network (Macaca mulatta)

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second shell of interactors

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proteins of unknown 3D structure

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

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Your Input:
	NOTCH1	Notch receptor 1. (2556 aa)
	BMPR2	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa)
	TBX5	T-box transcription factor 5. (518 aa)
	MKS1	MKS transition zone complex subunit 1. (559 aa)
	BMP10	Bone morphogenetic protein 10. (424 aa)
	SMAD4	Mothers against decapentaplegic homolog. (552 aa)
	HAND2	BHLH domain-containing protein. (186 aa)
	EYA1	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (621 aa)
	CTNNB1	Catenin beta-1. (781 aa)
	ISL1	ISL LIM homeobox 1. (413 aa)
	LOC719232	Serine/threonine-protein kinase; Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation. Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily. (313 aa)
	ENSMMUP00000073690	Serine/threonine-protein kinase; Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation. Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily. (403 aa)
	BMP4	Bone morphogenetic protein 4. (408 aa)
	TBX3	T-box transcription factor 3. (743 aa)

Your Current Organism:

Macaca mulatta

NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BMP10	BMP4	ENSMMUP00000019731	ENSMMUP00000077296	Bone morphogenetic protein 10.	Bone morphogenetic protein 4.	0.429
BMP10	BMPR2	ENSMMUP00000019731	ENSMMUP00000011799	Bone morphogenetic protein 10.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.991
BMP10	SMAD4	ENSMMUP00000019731	ENSMMUP00000024106	Bone morphogenetic protein 10.	Mothers against decapentaplegic homolog.	0.610
BMP4	BMP10	ENSMMUP00000077296	ENSMMUP00000019731	Bone morphogenetic protein 4.	Bone morphogenetic protein 10.	0.429
BMP4	BMPR2	ENSMMUP00000077296	ENSMMUP00000011799	Bone morphogenetic protein 4.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.992
BMP4	CTNNB1	ENSMMUP00000077296	ENSMMUP00000062910	Bone morphogenetic protein 4.	Catenin beta-1.	0.402
BMP4	ISL1	ENSMMUP00000077296	ENSMMUP00000063915	Bone morphogenetic protein 4.	ISL LIM homeobox 1.	0.582
BMP4	NOTCH1	ENSMMUP00000077296	ENSMMUP00000022401	Bone morphogenetic protein 4.	Notch receptor 1.	0.509
BMP4	SMAD4	ENSMMUP00000077296	ENSMMUP00000024106	Bone morphogenetic protein 4.	Mothers against decapentaplegic homolog.	0.887
BMP4	TBX3	ENSMMUP00000077296	ENSMMUP00000079291	Bone morphogenetic protein 4.	T-box transcription factor 3.	0.604
BMP4	TBX5	ENSMMUP00000077296	ENSMMUP00000015631	Bone morphogenetic protein 4.	T-box transcription factor 5.	0.565
BMPR2	BMP10	ENSMMUP00000011799	ENSMMUP00000019731	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Bone morphogenetic protein 10.	0.991
BMPR2	BMP4	ENSMMUP00000011799	ENSMMUP00000077296	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Bone morphogenetic protein 4.	0.992
BMPR2	CTNNB1	ENSMMUP00000011799	ENSMMUP00000062910	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Catenin beta-1.	0.477
BMPR2	SMAD4	ENSMMUP00000011799	ENSMMUP00000024106	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Mothers against decapentaplegic homolog.	0.892
CTNNB1	BMP4	ENSMMUP00000062910	ENSMMUP00000077296	Catenin beta-1.	Bone morphogenetic protein 4.	0.402
CTNNB1	BMPR2	ENSMMUP00000062910	ENSMMUP00000011799	Catenin beta-1.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.477
CTNNB1	NOTCH1	ENSMMUP00000062910	ENSMMUP00000022401	Catenin beta-1.	Notch receptor 1.	0.683
CTNNB1	SMAD4	ENSMMUP00000062910	ENSMMUP00000024106	Catenin beta-1.	Mothers against decapentaplegic homolog.	0.758
CTNNB1	TBX5	ENSMMUP00000062910	ENSMMUP00000015631	Catenin beta-1.	T-box transcription factor 5.	0.735