STRINGSTRING
PARP1 PARP1 RTEL1 RTEL1 OOEP OOEP PPP4C PPP4C SLF1 SLF1 BRD8 BRD8 ARID1B ARID1B PML PML MAGEF1 MAGEF1 BCL7C BCL7C DPF1 DPF1 SMARCE1 SMARCE1 PARPBP PARPBP FH FH TERF2IP TERF2IP SMARCD1 SMARCD1 ACTL6B ACTL6B OTUB2 OTUB2 AUNIP AUNIP ATR ATR WRAP53 WRAP53 SMARCB1 SMARCB1 SMARCC1 SMARCC1 LOC705671 LOC705671 ACTL6A ACTL6A UBQLN4 UBQLN4 KHDC3L KHDC3L MGMT MGMT SMARCA4 SMARCA4 UBE2V2 UBE2V2 BCL7A BCL7A ARID1A ARID1A SHLD2 SHLD2 RADX RADX HSF1 HSF1 RAD51AP1 RAD51AP1 SMARCA2 SMARCA2 PHF10 PHF10 HELQ HELQ PRKDC PRKDC ARID2 ARID2 HELB HELB PPP4R2 PPP4R2 TP53BP1 TP53BP1 PBRM1 PBRM1 EP400 EP400 SETMAR SETMAR FANCB FANCB ERCC6 ERCC6 FOXM1 FOXM1 CGAS CGAS FUS FUS KAT5 KAT5 SIRT6 SIRT6 POT1 POT1 UBR5 UBR5 POGZ POGZ SETD2 SETD2 TIMELESS TIMELESS PARP3 PARP3 EPC2 EPC2 PNKP PNKP SPIRE2 SPIRE2 RAD51 RAD51 ZCWPW1 ZCWPW1 CHEK1 CHEK1 RUVBL1 RUVBL1 OGG1 OGG1 DDX11 DDX11 DMAP1 DMAP1 MAD2L2 MAD2L2 TRIP12 TRIP12 SLF2 SLF2 ACTG1 ACTG1 WDR48 WDR48 MRGBP MRGBP MMS19 MMS19 HMGA2 HMGA2 RBBP8 RBBP8 SMARCD2 SMARCD2 POLQ POLQ YEATS4 YEATS4 UBE2N UBE2N MBTD1 MBTD1 TRRAP TRRAP ACTB ACTB DPF3 DPF3 KDM1A KDM1A NSD2 NSD2 WAS WAS FAM178B FAM178B PARP9 PARP9 DEK DEK ENSMMUP00000058534 ENSMMUP00000058534 SMARCC2 SMARCC2 MRNIP MRNIP SPIDR SPIDR SIRT7 SIRT7 SMCHD1 SMCHD1 ENSMMUP00000061983 ENSMMUP00000061983 VPS72 VPS72 KMT5C KMT5C RIF1 RIF1 PIAS4 PIAS4 DTX3L DTX3L ENSMMUP00000065918 ENSMMUP00000065918 TEX15 TEX15 ENSMMUP00000066500 ENSMMUP00000066500 SHLD3 SHLD3 HDGFL2 HDGFL2 FMN2 FMN2 ENSMMUP00000067976 ENSMMUP00000067976 ENSMMUP00000068036 ENSMMUP00000068036 ENSMMUP00000068054 ENSMMUP00000068054 CYREN CYREN RUVBL2 RUVBL2 ACTR2 ACTR2 ENSMMUP00000070232 ENSMMUP00000070232 MEAF6 MEAF6 ENSMMUP00000070845 ENSMMUP00000070845 SMARCD3 SMARCD3 SPIRE1 SPIRE1 ING3 ING3 MORF4L2 MORF4L2 ENSMMUP00000073151 ENSMMUP00000073151 RECQL5 RECQL5 CMC4 CMC4 CCDC197 CCDC197 ENSMMUP00000075843 ENSMMUP00000075843 FBH1 FBH1 RMI2 RMI2 ENSMMUP00000077734 ENSMMUP00000077734 KMT5B KMT5B RNF169 RNF169 SHLD1 SHLD1 EPC1 EPC1 BCL7B BCL7B ENSMMUP00000079633 ENSMMUP00000079633 KLHL15 KLHL15 ENSMMUP00000080573 ENSMMUP00000080573
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PARP1Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1014 aa)
RTEL1Regulator of telomere elongation helicase 1; ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by [...] (1297 aa)
OOEPOocyte expressed protein. (149 aa)
PPP4CSerine/threonine-protein phosphatase. (307 aa)
SLF1SMC5-SMC6 complex localization factor 1. (1059 aa)
BRD8Bromodomain containing 8. (1235 aa)
ARID1BAT-rich interaction domain 1B. (2428 aa)
PMLPromyelocytic leukemia protein. (882 aa)
MAGEF1MAGE family member F1. (300 aa)
BCL7CUncharacterized protein. (242 aa)
DPF1Zinc finger protein neuro-d4 isoform a. (414 aa)
SMARCE1SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1. (411 aa)
PARPBPPARP1 binding protein. (651 aa)
FHFumarate hydratase, mitochondrial. (510 aa)
TERF2IPTelomeric repeat-binding factor 2-interacting protein 1. (400 aa)
SMARCD1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1. (603 aa)
ACTL6BActin like 6B; Belongs to the actin family. (449 aa)
OTUB2OTU deubiquitinase, ubiquitin aldehyde binding 2. (259 aa)
AUNIPAurora kinase A and ninein interacting protein. (351 aa)
ATRATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2644 aa)
WRAP53Telomerase Cajal body protein 1. (548 aa)
SMARCB1SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1; Belongs to the SNF5 family. (385 aa)
SMARCC1SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1. (1132 aa)
LOC705671Uncharacterized protein. (398 aa)
ACTL6AActin-like protein 6A isoform 1; Belongs to the actin family. (429 aa)
UBQLN4Ubiquilin-4. (601 aa)
KHDC3LKH domain containing 3 like, subcortical maternal complex member. (206 aa)
MGMTMethylated-DNA--protein-cysteine methyltransferase. (238 aa)
SMARCA4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4. (1679 aa)
UBE2V2Ubiquitin-conjugating enzyme E2 variant 2. (145 aa)
BCL7AB-cell CLL/lymphoma 7 protein family member A isoform a. (231 aa)
ARID1AAT-rich interaction domain 1A. (2287 aa)
SHLD2FAM35_C domain-containing protein. (881 aa)
RADXUncharacterized protein. (855 aa)
HSF1Heat shock transcription factor 1. (507 aa)
RAD51AP1RAD51 associated protein 1. (352 aa)
SMARCA2SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2. (1586 aa)
PHF10PHD finger protein 10. (563 aa)
HELQHelicase, POLQ like. (1101 aa)
PRKDCProtein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family. (4128 aa)
ARID2AT-rich interaction domain 2. (1836 aa)
HELBDNA helicase B. (1087 aa)
PPP4R2Uncharacterized protein. (422 aa)
TP53BP1Tumor protein p53 binding protein 1. (1977 aa)
PBRM1Polybromo 1. (1655 aa)
EP400E1A binding protein p400. (3045 aa)
SETMARSET domain and mariner transposase fusion gene. (684 aa)
FANCBFA complementation group B. (858 aa)
ERCC6ERCC excision repair 6, chromatin remodeling factor. (2061 aa)
FOXM1Forkhead box protein M1 isoform 2. (770 aa)
CGASCyclic GMP-AMP synthase. (573 aa)
FUSTripartite motif containing 72. (534 aa)
KAT5Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (514 aa)
SIRT6NAD-dependent deacetylase sirtuin-6. (355 aa)
POT1Protection of telomeres 1. (658 aa)
UBR5Ubiquitin protein ligase E3 component n-recognin 5. (2806 aa)
POGZPogo transposable element derived with ZNF domain. (1492 aa)
SETD2SET domain containing 2, histone lysine methyltransferase. (2565 aa)
TIMELESSTimeless circadian regulator. (1204 aa)
PARP3Poly [ADP-ribose] polymerase. (532 aa)
EPC2Enhancer of polycomb homolog. (783 aa)
PNKPPolynucleotide kinase 3'-phosphatase. (532 aa)
SPIRE2Spire type actin nucleation factor 2. (714 aa)
RAD51RAD51 recombinase; Belongs to the RecA family. (380 aa)
ZCWPW1Zinc finger CW-type and PWWP domain containing 1. (649 aa)
CHEK1STT3 oligosaccharyltransferase complex catalytic subunit A. (768 aa)
RUVBL1RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (456 aa)
OGG1ENDO3c domain-containing protein. (395 aa)
DDX11DEAD/H-box helicase 11. (970 aa)
DMAP1DNA methyltransferase 1 associated protein 1. (612 aa)
MAD2L2Mitotic arrest deficient 2 like 2. (212 aa)
TRIP12Thyroid hormone receptor interactor 12. (2025 aa)
SLF2Uncharacterized protein. (1187 aa)
ACTG1Actin, cytoplasmic 2. (375 aa)
WDR48WD repeat domain 48. (745 aa)
MRGBPMRG domain binding protein. (204 aa)
MMS19MMS19 homolog, cytosolic iron-sulfur assembly component. (1030 aa)
HMGA2High mobility group AT-hook 2. (147 aa)
RBBP8Uncharacterized protein. (898 aa)
SMARCD2SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2. (470 aa)
POLQDNA polymerase theta. (2638 aa)
YEATS4YEATS domain-containing protein 4. (227 aa)
UBE2NUBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (210 aa)
MBTD1Mbt domain containing 1. (754 aa)
TRRAPTransformation/transcription domain associated protein; Belongs to the PI3/PI4-kinase family. (3873 aa)
ACTBUncharacterized protein. (421 aa)
DPF3Double PHD fingers 3. (410 aa)
KDM1ALysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (872 aa)
NSD2Uncharacterized protein. (1362 aa)
WASWASP actin nucleation promoting factor. (503 aa)
FAM178BFamily with sequence similarity 178 member B. (679 aa)
PARP9Poly(ADP-ribose) polymerase family member 9. (818 aa)
DEKProtein DEK isoform 1. (375 aa)
ENSMMUP00000058534UBIQUITIN_CONJUGAT_2 domain-containing protein. (145 aa)
SMARCC2SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 2. (1244 aa)
MRNIPMRN complex interacting protein. (346 aa)
SPIDRScaffold protein involved in DNA repair. (946 aa)
SIRT7Sirtuin 7. (421 aa)
SMCHD1Structural maintenance of chromosomes flexible hinge domain-containing protein 1. (2005 aa)
ENSMMUP00000061983Uncharacterized protein. (134 aa)
VPS72Vacuolar protein sorting-associated protein 72 homolog. (364 aa)
KMT5CLysine methyltransferase 5C. (461 aa)
RIF1Replication timing regulatory factor 1. (2466 aa)
PIAS4Protein inhibitor of activated STAT 4. (561 aa)
DTX3LDeltex E3 ubiquitin ligase 3L. (740 aa)
ENSMMUP00000065918Uncharacterized protein. (117 aa)
TEX15Testis expressed 15, meiosis and synapsis associated. (3155 aa)
ENSMMUP00000066500Uncharacterized protein. (236 aa)
SHLD3Shieldin complex subunit 3. (250 aa)
HDGFL2LEDGF domain-containing protein. (680 aa)
FMN2Formin 2. (1833 aa)
ENSMMUP00000067976Uncharacterized protein. (120 aa)
ENSMMUP00000068036Uncharacterized protein. (134 aa)
ENSMMUP00000068054Uncharacterized protein. (102 aa)
CYRENModulator of retrovirus infection homolog. (158 aa)
RUVBL2RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (497 aa)
ACTR2Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (399 aa)
ENSMMUP00000070232Uncharacterized protein. (121 aa)
MEAF6MYST/Esa1 associated factor 6. (203 aa)
ENSMMUP00000070845Uncharacterized protein. (200 aa)
SMARCD3SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3. (533 aa)
SPIRE1Spire type actin nucleation factor 1. (815 aa)
ING3Inhibitor of growth protein. (418 aa)
MORF4L2Mortality factor 4 like 2. (288 aa)
ENSMMUP00000073151zf-H2C2 domain-containing protein. (185 aa)
RECQL5RecQ like helicase 5. (1027 aa)
CMC4Uncharacterized protein. (92 aa)
CCDC197Uncharacterized protein. (579 aa)
ENSMMUP00000075843Uncharacterized protein. (341 aa)
FBH1F-box DNA helicase 1. (1088 aa)
RMI2Uncharacterized protein. (147 aa)
ENSMMUP00000077734Uncharacterized protein. (122 aa)
KMT5BHistone-lysine N-methyltransferase SUV420H1 isoform 1. (885 aa)
RNF169Ring finger protein 169. (709 aa)
SHLD1Shieldin complex subunit 1. (228 aa)
EPC1Enhancer of polycomb homolog. (836 aa)
BCL7BUncharacterized protein. (251 aa)
ENSMMUP00000079633FAM35_C domain-containing protein. (120 aa)
KLHL15BTB domain-containing protein. (658 aa)
ENSMMUP00000080573Uncharacterized protein. (121 aa)
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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