STRINGSTRING
GTF2H3 GTF2H3 GTF2H1 GTF2H1 GTF2H5 GTF2H5 CDK7 CDK7 BRD4 BRD4 CDK9 CDK9 GTF2H4 GTF2H4 CDK12 CDK12 CCNH CCNH GTF2H2 GTF2H2 ERCC2 ERCC2 MNAT1 MNAT1 CCNT2 CCNT2 F7GDN6_MACMU F7GDN6_MACMU HEXIM1 HEXIM1 CCNT1 CCNT1 SH3BP5L SH3BP5L IAH1 IAH1 CDK13 CDK13
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GTF2H3General transcription factor IIH subunit 3. (308 aa)
GTF2H1General transcription factor IIH subunit 1. (548 aa)
GTF2H5General transcription factor IIH subunit 5. (71 aa)
CDK7Cyclin-dependent kinase 7; Belongs to the protein kinase superfamily. (346 aa)
BRD4Bromodomain containing 4. (1334 aa)
CDK9Cyclin-dependent kinase 9; Belongs to the protein kinase superfamily. (372 aa)
GTF2H4General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (462 aa)
CDK12Cyclin-dependent kinase 12 isoform 2. (1481 aa)
CCNHCyclin H; Belongs to the cyclin family. (331 aa)
GTF2H2General transcription factor IIH subunit. (399 aa)
ERCC2TFIIH basal transcription factor complex helicase XPD subunit isoform 1. (760 aa)
MNAT1CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (309 aa)
CCNT2Cyclin T2; Belongs to the cyclin family. (709 aa)
F7GDN6_MACMUProtein kinase domain-containing protein. (165 aa)
HEXIM1Protein HEXIM1. (359 aa)
CCNT1Cyclin T1; Belongs to the cyclin family. (728 aa)
SH3BP5LSH3 binding domain protein 5 like. (447 aa)
IAH1Isoamyl acetate-hydrolyzing esterase 1 homolog. (248 aa)
CDK13Cyclin dependent kinase 13. (1511 aa)
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.