(12 nodes) U2-type prespliceosome network (Macaca mulatta)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LSM7	LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated. (107 aa)
	PRPF39	Pre-mRNA processing factor 39. (671 aa)
	LOC711104	Uncharacterized protein. (458 aa)
	LUC7L3	LUC7 like 3 pre-mRNA splicing factor. (489 aa)
	SNRNP70	Small nuclear ribonucleoprotein U1 subunit 70. (428 aa)
	SF3A1	Splicing factor 3A subunit 1 isoform 1. (793 aa)
	U2AF2	U2 snRNP auxiliary factor large subunit; Necessary for the splicing of pre-mRNA. Belongs to the splicing factor SR family. (471 aa)
	LUC7L	Putative RNA-binding protein Luc7-like 1 isoform b. (371 aa)
	ENSMMUP00000070804	Sm domain-containing protein. (166 aa)
	PRPF40A	Pre-mRNA processing factor 40 homolog A. (957 aa)
	SNRPN	Small nuclear ribonucleoprotein-associated protein. (240 aa)
	PRPF40B	Pre-mRNA processing factor 40 homolog B. (892 aa)

Your Current Organism:

Macaca mulatta

NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSMMUP00000070804	LOC711104	ENSMMUP00000070804	ENSMMUP00000045321	Sm domain-containing protein.	Uncharacterized protein.	0.662
ENSMMUP00000070804	LSM7	ENSMMUP00000070804	ENSMMUP00000047537	Sm domain-containing protein.	LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated.	0.818
ENSMMUP00000070804	LUC7L	ENSMMUP00000070804	ENSMMUP00000079051	Sm domain-containing protein.	Putative RNA-binding protein Luc7-like 1 isoform b.	0.662
ENSMMUP00000070804	LUC7L3	ENSMMUP00000070804	ENSMMUP00000034841	Sm domain-containing protein.	LUC7 like 3 pre-mRNA splicing factor.	0.523
ENSMMUP00000070804	PRPF39	ENSMMUP00000070804	ENSMMUP00000046125	Sm domain-containing protein.	Pre-mRNA processing factor 39.	0.747
ENSMMUP00000070804	PRPF40B	ENSMMUP00000070804	ENSMMUP00000057375	Sm domain-containing protein.	Pre-mRNA processing factor 40 homolog B.	0.570
ENSMMUP00000070804	SF3A1	ENSMMUP00000070804	ENSMMUP00000007333	Sm domain-containing protein.	Splicing factor 3A subunit 1 isoform 1.	0.906
ENSMMUP00000070804	SNRNP70	ENSMMUP00000070804	ENSMMUP00000031530	Sm domain-containing protein.	Small nuclear ribonucleoprotein U1 subunit 70.	0.787
LOC711104	ENSMMUP00000070804	ENSMMUP00000045321	ENSMMUP00000070804	Uncharacterized protein.	Sm domain-containing protein.	0.662
LOC711104	LSM7	ENSMMUP00000045321	ENSMMUP00000047537	Uncharacterized protein.	LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated.	0.574
LOC711104	LUC7L	ENSMMUP00000045321	ENSMMUP00000079051	Uncharacterized protein.	Putative RNA-binding protein Luc7-like 1 isoform b.	0.575
LOC711104	LUC7L3	ENSMMUP00000045321	ENSMMUP00000034841	Uncharacterized protein.	LUC7 like 3 pre-mRNA splicing factor.	0.651
LOC711104	PRPF39	ENSMMUP00000045321	ENSMMUP00000046125	Uncharacterized protein.	Pre-mRNA processing factor 39.	0.965
LOC711104	PRPF40A	ENSMMUP00000045321	ENSMMUP00000070269	Uncharacterized protein.	Pre-mRNA processing factor 40 homolog A.	0.727
LOC711104	PRPF40B	ENSMMUP00000045321	ENSMMUP00000057375	Uncharacterized protein.	Pre-mRNA processing factor 40 homolog B.	0.898
LOC711104	SF3A1	ENSMMUP00000045321	ENSMMUP00000007333	Uncharacterized protein.	Splicing factor 3A subunit 1 isoform 1.	0.769
LOC711104	SNRNP70	ENSMMUP00000045321	ENSMMUP00000031530	Uncharacterized protein.	Small nuclear ribonucleoprotein U1 subunit 70.	0.884
LOC711104	SNRPN	ENSMMUP00000045321	ENSMMUP00000066890	Uncharacterized protein.	Small nuclear ribonucleoprotein-associated protein.	0.662
LOC711104	U2AF2	ENSMMUP00000045321	ENSMMUP00000006397	Uncharacterized protein.	U2 snRNP auxiliary factor large subunit; Necessary for the splicing of pre-mRNA. Belongs to the splicing factor SR family.	0.879
LSM7	ENSMMUP00000070804	ENSMMUP00000047537	ENSMMUP00000070804	LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated.	Sm domain-containing protein.	0.818