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LRRTM1 LRRTM1 GABRP GABRP ERBB4 ERBB4 DRD5 DRD5 CLSTN2 CLSTN2 STX1B STX1B GLRA4 GLRA4 NLGN1 NLGN1 CLSTN1 CLSTN1 GRIP2 GRIP2 ZC4H2 ZC4H2 MUSK MUSK CHRNB4 CHRNB4 SLC1A7 SLC1A7 DNAJA3 DNAJA3 CNTN6 CNTN6 CLSTN3 CLSTN3 PDLIM4 PDLIM4 GABRA4 GABRA4 PRRT2 PRRT2 MARCKSL1 MARCKSL1 GRM5 GRM5 CHRNA5 CHRNA5 GABRE GABRE PCDH19 PCDH19 ATP2B3 ATP2B3 PTPRS PTPRS CACNA1C CACNA1C LOC694442 LOC694442 DNM1 DNM1 SHISA9 SHISA9 CHRM5 CHRM5 OTOF OTOF DRD2 DRD2 DNM2 DNM2 GABRR1 GABRR1 SHISA8 SHISA8 CDH2 CDH2 LRRC4 LRRC4 FER1L6 FER1L6 CNMD CNMD PLPPR3 PLPPR3 PRRT1 PRRT1 F6VLV0_MACMU F6VLV0_MACMU KPNA2 KPNA2 CHRM1 CHRM1 CHRNB1 CHRNB1 ABHD17B ABHD17B SYAP1 SYAP1 UTRN UTRN STX11 STX11 GABRR2 GABRR2 PICALM PICALM ATP2B2 ATP2B2 PPP1R9B PPP1R9B NETO1 NETO1 PLPPR4 PLPPR4 CHRM3 CHRM3 CHRNA1 CHRNA1 CHRNG CHRNG PCDH17 PCDH17 CHRNA7 CHRNA7 ATP2B1 ATP2B1 GABRG3 GABRG3 GPHN GPHN TENM2 TENM2 SNCAIP SNCAIP MPP6 MPP6 HIP1 HIP1 TRPV1 TRPV1 LRRTM4 LRRTM4 STRN STRN DLG2 DLG2 CACNG2 CACNG2 SLC1A2 SLC1A2 LRP4 LRP4 ATP6AP2 ATP6AP2 ITSN1 ITSN1 LIN7B LIN7B STX19 STX19 STX2 STX2 GRID2IP GRID2IP NLGN3 NLGN3 MPP2 MPP2 STX1A STX1A NRXN1 NRXN1 RAPSN RAPSN PI4K2A PI4K2A SNAP91 SNAP91 CHRM4 CHRM4 CHRND CHRND GPER1 GPER1 CACNA1D CACNA1D CNTN2 CNTN2 ZDBF2 ZDBF2 SYT11 SYT11 ATAD1 ATAD1 SHC4 SHC4 F2R F2R LOC703257 LOC703257 CHRNA2 CHRNA2 CNIH2 CNIH2 DNM3 DNM3 GABRQ GABRQ CNTNAP4 CNTNAP4 ADGRL1 ADGRL1 CHRNB3 CHRNB3 ENSMMUP00000064060 ENSMMUP00000064060 NRG1 NRG1 MAGEE1 MAGEE1 LRRTM2 LRRTM2 LRRC4B LRRC4B NECTIN1 NECTIN1 CADM3 CADM3 HTR3A HTR3A CHRNE CHRNE ENSMMUP00000068263 ENSMMUP00000068263 DLG4 DLG4 ENSMMUP00000068605 ENSMMUP00000068605 GABRD GABRD GABRA3 GABRA3 GABRG1 GABRG1 ENSMMUP00000072478 ENSMMUP00000072478 ENSMMUP00000072834 ENSMMUP00000072834 ADAM23 ADAM23 CNIH3 CNIH3 CHAD CHAD NLGN2 NLGN2 IGSF21 IGSF21 RGS7BP RGS7BP FLRT3 FLRT3 GSG1L GSG1L STX4 STX4 LOC100429145 LOC100429145 LRFN3 LRFN3 SHISA7 SHISA7 NPTN NPTN CHRNB2 CHRNB2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LRRTM1Leucine-rich repeat transmembrane neuronal protein 1. (522 aa)
GABRPGamma-aminobutyric acid type A receptor pi subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (460 aa)
ERBB4Receptor protein-tyrosine kinase. (1308 aa)
DRD5D(1B) dopamine receptor; Dopamine receptor whose activity is mediated by G proteins which activate adenylyl cyclase; Belongs to the G-protein coupled receptor 1 family. (478 aa)
CLSTN2Calsyntenin 2. (955 aa)
STX1BSyntaxin 1B; Belongs to the syntaxin family. (289 aa)
GLRA4Glycine receptor alpha 4; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (457 aa)
NLGN1Neuroligin-1. (823 aa)
CLSTN1Calsyntenin 1. (1114 aa)
GRIP2Glutamate receptor interacting protein 2. (1043 aa)
ZC4H2Zinc finger C4H2 domain-containing protein isoform 1. (224 aa)
MUSKMuscle associated receptor tyrosine kinase. (869 aa)
CHRNB4Cholinergic receptor nicotinic beta 4 subunit. (492 aa)
SLC1A7Amino acid transporter. (619 aa)
DNAJA3DnaJ heat shock protein family (Hsp40) member A3. (480 aa)
CNTN6Neural recognition molecule NB-3. (1029 aa)
CLSTN3Calsyntenin 3. (960 aa)
PDLIM4PDZ and LIM domain protein 4 isoform 1. (330 aa)
GABRA4Gamma-aminobutyric acid type A receptor alpha4 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (554 aa)
PRRT2Proline-rich transmembrane protein 2 isoform 1. (340 aa)
MARCKSL1MARCKS-related protein. (195 aa)
GRM5Metabotropic glutamate receptor 5 isoform a. (1212 aa)
CHRNA5Cholinergic receptor nicotinic alpha 5 subunit. (468 aa)
GABREGamma-aminobutyric acid type A receptor epsilon subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (506 aa)
PCDH19Protocadherin-19 isoform c. (1148 aa)
ATP2B3Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1220 aa)
PTPRSProtein tyrosine phosphatase receptor type S. (1948 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2186 aa)
LOC694442Protocadherin-8 isoform 2. (973 aa)
DNM1Dynamin-1 isoform 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (864 aa)
SHISA9Shisa family member 9. (424 aa)
CHRM5Muscarinic acetylcholine receptor M5; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover; Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily. CHRM5 sub-subfamily. (532 aa)
OTOFOtoferlin. (1996 aa)
DRD2Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. (490 aa)
DNM2Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (880 aa)
GABRR1Gamma-aminobutyric acid type A receptor rho1 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (480 aa)
SHISA8Shisa family member 8. (398 aa)
CDH2Cadherin-2 preproprotein; Cadherins are calcium-dependent cell adhesion proteins. (906 aa)
LRRC4Leucine-rich repeat-containing protein 4. (653 aa)
FER1L6Fer-1 like family member 6. (1857 aa)
CNMDLeukocyte cell-derived chemotaxin 1 isoform 1. (334 aa)
PLPPR3Phospholipid phosphatase related 3. (719 aa)
PRRT1Uncharacterized protein. (346 aa)
F6VLV0_MACMUUncharacterized protein. (278 aa)
KPNA2Importin subunit alpha; Functions in nuclear protein import. (529 aa)
CHRM1Muscarinic acetylcholine receptor M1; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover. (460 aa)
CHRNB1Cholinergic receptor nicotinic beta 1 subunit. (501 aa)
ABHD17BAbhydrolase domain-containing protein FAM108B1 isoform 1. (293 aa)
SYAP1Synapse-associated protein 1. (352 aa)
UTRNUtrophin. (3452 aa)
STX11Syntaxin 11; Belongs to the syntaxin family. (313 aa)
GABRR2Gamma-aminobutyric acid type A receptor rho2 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (465 aa)
PICALMPhosphatidylinositol binding clathrin assembly protein. (674 aa)
ATP2B2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1243 aa)
PPP1R9BProtein phosphatase 1 regulatory subunit 9B. (818 aa)
NETO1Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1. (533 aa)
PLPPR4Phospholipid phosphatase related 4. (763 aa)
CHRM3Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (590 aa)
CHRNA1Cholinergic receptor nicotinic alpha 1 subunit. (502 aa)
CHRNGCholinergic receptor nicotinic gamma subunit. (516 aa)
PCDH17Protocadherin-17. (1159 aa)
CHRNA7Neuronal acetylcholine receptor subunit alpha-7; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. The channel is blocked by alpha-bungarotoxin (By similarity). (502 aa)
ATP2B1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1249 aa)
GABRG3Gamma-aminobutyric acid type A receptor gamma3 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (467 aa)
GPHNGephyrin. (801 aa)
TENM2Teneurin transmembrane protein 2. (2653 aa)
SNCAIPSynuclein alpha interacting protein. (1017 aa)
MPP6Membrane palmitoylated protein 6; Belongs to the MAGUK family. (555 aa)
HIP1Huntingtin-interacting protein 1 isoform 1. (1037 aa)
TRPV1Transient receptor potential cation channel subfamily V member 1; Belongs to the transient receptor (TC 1.A.4) family. (839 aa)
LRRTM4Leucine rich repeat transmembrane neuronal 4. (565 aa)
STRNStriatin. (813 aa)
DLG2Discs large MAGUK scaffold protein 2. (975 aa)
CACNG2Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (323 aa)
SLC1A2Amino acid transporter. (611 aa)
LRP4Low-density lipoprotein receptor-related protein 4. (1905 aa)
ATP6AP2Renin/prorenin receptor. (350 aa)
ITSN1Intersectin 1. (1720 aa)
LIN7BLin-7 homolog B, crumbs cell polarity complex component. (309 aa)
STX19Syntaxin 19; Belongs to the syntaxin family. (294 aa)
STX2Syntaxin-2 isoform 2; Belongs to the syntaxin family. (288 aa)
GRID2IPGrid2 interacting protein. (1211 aa)
NLGN3Neuroligin-3; Cell surface protein involved in cell-cell-interactions via its interactions with neurexin family members. Plays a role in synapse function and synaptic signal transmission, and probably mediates its effects by recruiting and clustering other synaptic proteins. May promote the initial formation of synapses, but is not essential for this. May also play a role in glia-glia or glia-neuron interactions in the developing peripheral nervous system (By similarity). (848 aa)
MPP2Uncharacterized protein; Belongs to the MAGUK family. (594 aa)
STX1ASyntaxin-1A isoform 1; Belongs to the syntaxin family. (288 aa)
NRXN1Uncharacterized protein. (1547 aa)
RAPSNReceptor associated protein of the synapse. (516 aa)
PI4K2APhosphatidylinositol 4-kinase type 2 alpha. (480 aa)
SNAP91Synaptosome associated protein 91. (908 aa)
CHRM4Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (479 aa)
CHRNDCholinergic receptor nicotinic delta subunit. (573 aa)
GPER1G-protein coupled estrogen receptor 1; G-protein coupled estrogen receptor that binds to 17-beta- estradiol (E2) with high affinity, leading to rapid and transient activation of numerous intracellular signaling pathways. Stimulates cAMP production, calcium mobilization and tyrosine kinase Src inducing the release of heparin-bound epidermal growth factor (HB-EGF) and subsequent transactivation of the epidermal growth factor receptor (EGFR), activating downstream signaling pathways such as PI3K/Akt and ERK/MAPK. Mediates pleiotropic functions among others in the cardiovascular, endocrine [...] (375 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2181 aa)
CNTN2Uncharacterized protein. (1040 aa)
ZDBF2Zinc finger DBF-type containing 2. (2357 aa)
SYT11Synaptotagmin-11. (431 aa)
ATAD1ATPase family AAA domain-containing protein 1; Belongs to the AAA ATPase family. (361 aa)
SHC4Src-like proteiny 2 domain-containing-transforming protein C4. (630 aa)
F2RCoagulation factor II thrombin receptor; Belongs to the G-protein coupled receptor 1 family. (425 aa)
LOC703257ENTH domain-containing protein. (344 aa)
CHRNA2Cholinergic receptor nicotinic alpha 2 subunit. (530 aa)
CNIH2Cornichon family AMPA receptor auxiliary protein 2. (160 aa)
DNM3Dynamin 3; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (869 aa)
GABRQGamma-aminobutyric acid type A receptor theta subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (632 aa)
CNTNAP4Contactin associated protein like 4. (1308 aa)
ADGRL1Adhesion G protein-coupled receptor L1; Belongs to the G-protein coupled receptor 2 family. (1511 aa)
CHRNB3Neuronal acetylcholine receptor subunit beta-3. (458 aa)
ENSMMUP00000064060FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (149 aa)
NRG1Neuregulin 1. (700 aa)
MAGEE1MAGE family member E1. (887 aa)
LRRTM2Leucine-rich repeat transmembrane neuronal protein 2. (516 aa)
LRRC4BLeucine-rich repeat-containing protein 4B. (713 aa)
NECTIN1Poliovirus receptor-related protein 1 isoform 1. (519 aa)
CADM3Cell adhesion molecule 3 isoform 1. (430 aa)
HTR3A5-hydroxytryptamine receptor 3A; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (485 aa)
CHRNECholinergic receptor nicotinic epsilon subunit. (493 aa)
ENSMMUP00000068263Uncharacterized protein. (149 aa)
DLG4Uncharacterized protein; Belongs to the MAGUK family. (972 aa)
ENSMMUP00000068605Uncharacterized protein. (107 aa)
GABRDGamma-aminobutyric acid type A receptor delta subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (484 aa)
GABRA3Gamma-aminobutyric acid type A receptor alpha3 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (492 aa)
GABRG1Gamma-aminobutyric acid type A receptor gamma1 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (478 aa)
ENSMMUP00000072478Uncharacterized protein. (103 aa)
ENSMMUP00000072834Uncharacterized protein. (612 aa)
ADAM23ADAM metallopeptidase domain 23. (852 aa)
CNIH3Cornichon family AMPA receptor auxiliary protein 3. (183 aa)
CHADUncharacterized protein. (440 aa)
NLGN2COesterase domain-containing protein. (836 aa)
IGSF21Uncharacterized protein. (501 aa)
RGS7BPRegulator of G protein signaling 7 binding protein. (321 aa)
FLRT3Fibronectin-like domain-containing leucine-rich transmembrane protein 3. (649 aa)
GSG1LGSG1 like. (352 aa)
STX4Syntaxin 4; Belongs to the syntaxin family. (322 aa)
LOC100429145Uncharacterized protein. (1309 aa)
LRFN3Leucine-rich repeat and fibronectin type-III domain-containing protein 3. (628 aa)
SHISA7Shisa family member 7. (659 aa)
NPTNNeuroplastin isoform c. (394 aa)
CHRNB2Neuronal acetylcholine receptor subunit beta-2. (502 aa)
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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