STRINGSTRING
ACAN ACAN IMPG2 IMPG2 ADAM21 ADAM21 FBN2 FBN2 TIE1 TIE1 HMCN1 HMCN1 SLIT1 SLIT1 ITGB8 ITGB8 NTNG2 NTNG2 UMOD UMOD HGFAC HGFAC TENM3 TENM3 MASP2 MASP2 LRP8 LRP8 HHIP HHIP MEGF11 MEGF11 CNTNAP1 CNTNAP1 FBLN5 FBLN5 ADAM2 ADAM2 MEGF6 MEGF6 ADAM12 ADAM12 LRP1B LRP1B PLAU PLAU EGF EGF ATRAID ATRAID NRG2 NRG2 CCBE1 CCBE1 TNN TNN TNXB TNXB F7 F7 PROZ PROZ HEG1 HEG1 HABP2 HABP2 SVEP1 SVEP1 MATN3 MATN3 ATRNL1 ATRNL1 DNER DNER FBLN7 FBLN7 LAMC3 LAMC3 EPGN EPGN AREG AREG FBLN1 FBLN1 FRAS1 FRAS1 SLIT2 SLIT2 VWCE VWCE ITGBL1 ITGBL1 TNC TNC MATN4 MATN4 FAT2 FAT2 FBN1 FBN1 PAMR1 PAMR1 THBS1 THBS1 SCUBE1 SCUBE1 TEK TEK CRB2 CRB2 STAB2 STAB2 COMP COMP LAMB1 LAMB1 CAVIN4 CAVIN4 ADAM11 ADAM11 FBLN2 FBLN2 EREG EREG LOC713632 LOC713632 LAMC2 LAMC2 LOC100429145 LOC100429145 GAS6 GAS6 LAMA4 LAMA4 ADGRE5 ADGRE5 LRP2 LRP2 TBCEL TBCEL TDGF1 TDGF1 LOC711939 LOC711939 FAT3 FAT3 BTC BTC JAG2 JAG2 CRELD2 CRELD2 HSPG2 HSPG2 ADAM23 ADAM23 MMRN1 MMRN1 TENM4 TENM4 DLK2 DLK2 FBN3 FBN3 LOC114679594 LOC114679594 MATN2 MATN2 EGFL7 EGFL7 SLIT3 SLIT3 PEAR1 PEAR1 NAGPA NAGPA MUC12 MUC12 VCAN VCAN ADAM19 ADAM19 NCAN NCAN ADAM30 ADAM30 EDIL3 EDIL3 DLL4 DLL4 SCUBE3 SCUBE3 ENSMMUP00000065554 ENSMMUP00000065554 MATN1 MATN1 ADAM1 ADAM1 THBS2 THBS2 LOC713573 LOC713573 LRP6 LRP6 LAMB3 LAMB3 NRG1 NRG1 BCAN BCAN MUC3A MUC3A TNR TNR ADGRE2 ADGRE2 CNTNAP4 CNTNAP4 HBEGF HBEGF CFC1 CFC1 TMEM8B TMEM8B VASN VASN HMCN2 HMCN2 PLAT PLAT ASTN1 ASTN1 SNED1 SNED1 EFEMP1 EFEMP1 OTOG OTOG SCUBE2 SCUBE2 TMEFF2 TMEFF2 RELN RELN MUC4 MUC4 CRELD1 CRELD1 LOC709999 LOC709999 TENM1 TENM1 MEP1B MEP1B SELL SELL LRP1 LRP1 LAMB4 LAMB4 TLL1 TLL1 LDLR LDLR LAMB2 LAMB2 SELE SELE ENSMMUP00000049781 ENSMMUP00000049781 MEGF10 MEGF10 AGRN AGRN MFGE8 MFGE8 NTNG1 NTNG1 EYS EYS NRXN1 NRXN1 NOTCH2 NOTCH2 TGFA TGFA LOC722133 LOC722133 THBS4 THBS4 MEGF8 MEGF8 NPNT NPNT LAMA3 LAMA3 PCSK5 PCSK5 THBS3 THBS3 LRP5 LRP5 SELP SELP ADAM33 ADAM33 EFEMP2 EFEMP2 LRP4 LRP4 NELL1 NELL1 TPO TPO MALRD1 MALRD1 F10 F10 UMODL1 UMODL1 SCARF1 SCARF1 VWDE VWDE FAT4 FAT4 FAT1 FAT1 TENM2 TENM2 NRG4 NRG4 PGAP6 PGAP6 CLEC18A CLEC18A ADAM28 ADAM28 ADAM9 ADAM9 LTBP3 LTBP3 ADAM15 ADAM15 ADGRL4 ADGRL4 ADAM8 ADAM8 MEP1A MEP1A ADAM22 ADAM22 EGFL6 EGFL6 NRXN2 NRXN2 VWA2 VWA2 ATRN ATRN LAMA2 LAMA2 ADAM18 ADAM18 ITGB4 ITGB4 LTBP1 LTBP1 DLL1 DLL1 SUSD1 SUSD1 CELSR1 CELSR1 LTBP4 LTBP4 OIT3 OIT3 PROS1 PROS1 F9 F9 DLK1 DLK1 ADGRE1 ADGRE1 F12 F12 CNTNAP5 CNTNAP5 DLL3 DLL3 NOTCH4 NOTCH4 NID2 NID2 JAG1 JAG1 AREL1 AREL1 NRG3 NRG3 STAB1 STAB1 NELL2 NELL2 KLHL22 KLHL22 EGFLAM EGFLAM NOTCH1 NOTCH1 WIF1 WIF1 PTGS2 PTGS2 THBD THBD CD93 CD93 CUBN CUBN CD248 CD248 MEGF9 MEGF9 TLL2 TLL2 CNTNAP2 CNTNAP2 CELSR2 CELSR2 VLDLR VLDLR LAMC1 LAMC1 CELSR3 CELSR3 MUC13 MUC13 NRXN3 NRXN3 NOTCH3 NOTCH3 BMP1 BMP1 MASP1 MASP1 PTGS1 PTGS1 NID1 NID1 CRB1 CRB1 PCSK6 PCSK6
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ACANAggrecan. (2266 aa)
IMPG2Interphotoreceptor matrix proteoglycan 2. (1242 aa)
ADAM21Uncharacterized protein. (722 aa)
FBN2Fibrillin 2. (2912 aa)
TIE1Tyrosine kinase with immunoglobulin like and EGF like domains 1. (1138 aa)
HMCN1Hemicentin 1. (5635 aa)
SLIT1Slit guidance ligand 1. (1534 aa)
ITGB8Integrin beta; Belongs to the integrin beta chain family. (822 aa)
NTNG2Netrin G2. (613 aa)
UMODUromodulin. (641 aa)
HGFACHGF activator. (657 aa)
TENM3Uncharacterized protein. (2699 aa)
MASP2Mannan binding lectin serine peptidase 2; Belongs to the peptidase S1 family. (686 aa)
LRP8LDL receptor related protein 8. (959 aa)
HHIPHedgehog-interacting protein. (700 aa)
MEGF11Multiple EGF like domains 11. (1044 aa)
CNTNAP1Uncharacterized protein. (1382 aa)
FBLN5Uncharacterized protein. (465 aa)
ADAM2ADAM metallopeptidase domain 2. (735 aa)
MEGF6Multiple EGF like domains 6. (1541 aa)
ADAM12ADAM metallopeptidase domain 12. (909 aa)
LRP1BLDL receptor related protein 1B. (4599 aa)
PLAUPlasminogen activator, urokinase. (430 aa)
EGFPro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1213 aa)
ATRAIDEGF-like domain-containing protein. (284 aa)
NRG2Neuregulin 2. (851 aa)
CCBE1Collagen and calcium binding EGF domains 1. (406 aa)
TNNTenascin N. (1299 aa)
TNXBUncharacterized protein. (4486 aa)
F7Coagulation factor VII. (526 aa)
PROZProtein Z, vitamin K dependent plasma glycoprotein; Belongs to the peptidase S1 family. (422 aa)
HEG1Heart development protein with EGF like domains 1. (1486 aa)
HABP2Hyaluronan binding protein 2. (560 aa)
SVEP1Sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1. (3571 aa)
MATN3Matrilin 3. (487 aa)
ATRNL1Attractin like 1. (1378 aa)
DNERDelta/notch like EGF repeat containing. (737 aa)
FBLN7Transmembrane protein 87B. (610 aa)
LAMC3Laminin subunit gamma 3. (1575 aa)
EPGNEpithelial mitogen. (154 aa)
AREGAmphiregulin. (252 aa)
FBLN1Fibulin-1; Incorporated into fibronectin-containing matrix fibers. May play a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM). Could be important for certain developmental processes and contribute to the supramolecular organization of ECM architecture, in particular to those of basement membranes. (703 aa)
FRAS1Fraser extracellular matrix complex subunit 1. (4011 aa)
SLIT2Slit guidance ligand 2. (1529 aa)
VWCEVon Willebrand factor C and EGF domains. (955 aa)
ITGBL1Integrin subunit beta like 1. (494 aa)
TNCTenascin C. (2201 aa)
MATN4Uncharacterized protein. (648 aa)
FAT2FAT atypical cadherin 2. (4349 aa)
FBN1Fibrillin-1. (2871 aa)
PAMR1Peptidase domain containing associated with muscle regeneration 1; Belongs to the peptidase S1 family. (720 aa)
THBS1Thrombospondin 1. (1170 aa)
SCUBE1Signal peptide, CUB domain and EGF like domain containing 1. (988 aa)
TEKTEK receptor tyrosine kinase. (1124 aa)
CRB2Crumbs cell polarity complex component 2. (1287 aa)
STAB2Stabilin 2. (2550 aa)
COMPCartilage oligomeric matrix protein. (757 aa)
LAMB1Laminin subunit beta 1. (1786 aa)
CAVIN4Uncharacterized protein. (454 aa)
ADAM11ADAM metallopeptidase domain 11. (786 aa)
FBLN2Fibulin 2. (1225 aa)
EREGProepiregulin. (169 aa)
LOC713632Uncharacterized protein. (742 aa)
LAMC2Laminin subunit gamma 2. (1301 aa)
LOC100429145Uncharacterized protein. (1309 aa)
GAS6Growth arrest specific 6. (684 aa)
LAMA4Laminin subunit alpha 4. (1832 aa)
ADGRE5Adhesion G protein-coupled receptor E5; Belongs to the G-protein coupled receptor 2 family. (1130 aa)
LRP2LDL receptor related protein 2. (4660 aa)
TBCELUncharacterized protein. (2155 aa)
TDGF1Growth factor; Belongs to the EGF-CFC (Cripto-1/FRL1/Cryptic) family. (182 aa)
LOC711939Uncharacterized protein. (1341 aa)
FAT3FAT atypical cadherin 3. (4612 aa)
BTCBetacellulin. (191 aa)
JAG2Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1290 aa)
CRELD2Uncharacterized protein. (670 aa)
HSPG2Heparan sulfate proteoglycan 2. (4680 aa)
ADAM23ADAM metallopeptidase domain 23. (852 aa)
MMRN1Multimerin 1. (1223 aa)
TENM4Teneurin transmembrane protein 4. (2929 aa)
DLK2Protein delta homolog 2. (383 aa)
FBN3Fibrillin 3. (2697 aa)
LOC114679594Uncharacterized protein. (743 aa)
MATN2Matrilin 2. (1249 aa)
EGFL7Epidermal growth factor-like protein 7. (273 aa)
SLIT3Slit guidance ligand 3. (1530 aa)
PEAR1Platelet endothelial aggregation receptor 1. (1037 aa)
NAGPAN-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase. (515 aa)
MUC12Uncharacterized protein. (3992 aa)
VCANVersican. (3397 aa)
ADAM19ADAM metallopeptidase domain 19. (944 aa)
NCANNeurocan. (1320 aa)
ADAM30ADAM metallopeptidase domain 30. (809 aa)
EDIL3EGF like repeats and discoidin domains 3. (486 aa)
DLL4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (713 aa)
SCUBE3Signal peptide, CUB domain and EGF like domain containing 3. (1009 aa)
ENSMMUP00000065554Uncharacterized protein. (459 aa)
MATN1Matrilin 1. (495 aa)
ADAM1Uncharacterized protein. (911 aa)
THBS2Thrombospondin 2. (1172 aa)
LOC713573Uncharacterized protein. (742 aa)
LRP6Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1613 aa)
LAMB3Laminin subunit beta 3. (1172 aa)
NRG1Neuregulin 1. (700 aa)
BCANBrevican. (945 aa)
MUC3AMucin 3A, cell surface associated. (4055 aa)
TNRUncharacterized protein. (1358 aa)
ADGRE2Adhesion G protein-coupled receptor E2; Cell surface receptor that binds to the chondroitin sulfate moiety of glycosaminoglycan chains and promotes cell attachment. Promotes granulocyte chemotaxis, degranulation and adhesion. In macrophages, promotes the release of inflammatory cytokines, including IL8 and TNF. Signals probably through G-proteins. (925 aa)
CNTNAP4Contactin associated protein like 4. (1308 aa)
HBEGFEGF-like domain-containing protein. (214 aa)
CFC1EGF-like domain-containing protein. (250 aa)
TMEM8BTransmembrane protein 8B. (924 aa)
VASNVasorin. (790 aa)
HMCN2Hemicentin 2. (5002 aa)
PLATPlasminogen activator; Belongs to the peptidase S1 family. (562 aa)
ASTN1Astrotactin-1 isoform 1. (1294 aa)
SNED1Sushi, nidogen and EGF like domains 1. (1432 aa)
EFEMP1EGF containing fibulin extracellular matrix protein 1. (516 aa)
OTOGOtogelin. (2917 aa)
SCUBE2Signal peptide, CUB domain and EGF like domain containing 2. (1076 aa)
TMEFF2Transmembrane protein with EGF like and two follistatin like domains 2. (374 aa)
RELNReelin. (3460 aa)
MUC4Uncharacterized protein. (1171 aa)
CRELD1Cysteine rich with EGF like domains 1. (549 aa)
LOC709999Uncharacterized protein. (831 aa)
TENM1Teneurin transmembrane protein 1. (2732 aa)
MEP1BMeprin A subunit. (743 aa)
SELLL-selectin; Calcium-dependent lectin that mediates cell adhesion by binding to glycoproteins on neighboring cells. Mediates the adherence of lymphocytes to endothelial cells of high endothelial venules in peripheral lymph nodes. Promotes initial tethering and rolling of leukocytes in endothelia; Belongs to the selectin/LECAM family. (397 aa)
LRP1LDL receptor related protein 1. (4561 aa)
LAMB4Laminin subunit beta 4. (1762 aa)
TLL1Metalloendopeptidase. (1013 aa)
LDLRUncharacterized protein. (918 aa)
LAMB2Laminin subunit beta-2. (1798 aa)
SELESelectin E. (610 aa)
ENSMMUP00000049781Uncharacterized protein. (474 aa)
MEGF10Multiple EGF like domains 10. (1137 aa)
AGRNAgrin. (2067 aa)
MFGE8Milk fat globule-EGF factor 8 protein. (387 aa)
NTNG1Netrin G1. (581 aa)
EYSEyes shut homolog. (3165 aa)
NRXN1Uncharacterized protein. (1547 aa)
NOTCH2Neurogenic locus notch homolog protein 2 isoform 1 preproprotein. (2471 aa)
TGFAProtransforming growth factor alpha; TGF alpha is a mitogenic polypeptide that is able to bind to the EGF receptor/EGFR and to act synergistically with TGF beta to promote anchorage-independent cell proliferation in soft agar. (166 aa)
LOC722133Uncharacterized protein; Belongs to the peptidase S1 family. (750 aa)
THBS4Thrombospondin 4. (987 aa)
MEGF8Multiple EGF like domains 8. (2789 aa)
NPNTNephronectin. (661 aa)
LAMA3Laminin subunit alpha 3. (3333 aa)
PCSK5Proprotein convertase subtilisin/kexin type 5; Belongs to the peptidase S8 family. (1887 aa)
THBS3Uncharacterized protein. (956 aa)
LRP5Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1612 aa)
SELPSelectin P. (830 aa)
ADAM33ADAM metallopeptidase domain 33. (813 aa)
EFEMP2EGF containing fibulin extracellular matrix protein 2. (576 aa)
LRP4Low-density lipoprotein receptor-related protein 4. (1905 aa)
NELL1Neural EGFL like 1. (838 aa)
TPOThyroid peroxidase. (930 aa)
MALRD1MAM and LDL receptor class A domain containing 1. (2157 aa)
F10Coagulation factor X. (488 aa)
UMODL1Uromodulin like 1. (852 aa)
SCARF1Scavenger receptor class F member 1. (841 aa)
VWDEVon Willebrand factor D and EGF domains. (1590 aa)
FAT4FAT atypical cadherin 4. (4983 aa)
FAT1FAT atypical cadherin 1. (4643 aa)
TENM2Teneurin transmembrane protein 2. (2653 aa)
NRG4Neuregulin 4. (125 aa)
PGAP6Transmembrane protein 8A. (771 aa)
CLEC18AUncharacterized protein. (455 aa)
ADAM28ADAM metallopeptidase domain 28. (790 aa)
ADAM9ADAM metallopeptidase domain 9. (848 aa)
LTBP3Latent transforming growth factor beta binding protein 3. (1185 aa)
ADAM15ADAM metallopeptidase domain 15. (919 aa)
ADGRL4Adhesion G protein-coupled receptor L4; Belongs to the G-protein coupled receptor 2 family. (690 aa)
ADAM8ADAM metallopeptidase domain 8. (823 aa)
MEP1AMeprin A subunit. (746 aa)
ADAM22ADAM metallopeptidase domain 22. (972 aa)
EGFL6EGF like domain multiple 6. (658 aa)
NRXN2Neurexin 2. (1713 aa)
VWA2Von Willebrand factor A domain containing 2. (787 aa)
ATRNAttractin isoform 1 preproprotein. (1430 aa)
LAMA2Laminin subunit alpha 2. (3122 aa)
ADAM18ADAM metallopeptidase domain 18. (739 aa)
ITGB4Integrin beta. (1823 aa)
LTBP1Latent transforming growth factor beta binding protein 1. (1720 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (723 aa)
SUSD1Sushi domain containing 1. (757 aa)
CELSR1Cadherin EGF LAG seven-pass G-type receptor 1; Belongs to the G-protein coupled receptor 2 family. (1818 aa)
LTBP4Latent transforming growth factor beta binding protein 4. (1624 aa)
OIT3Oncoprotein induced transcript 3. (545 aa)
PROS1Vitamin K-dependent protein S; Anticoagulant plasma protein; it is a cofactor to activated protein C in the degradation of coagulation factors Va and VIIIa. It helps to prevent coagulation and stimulating fibrinolysis. (676 aa)
F9Coagulation factor IX. (461 aa)
DLK1Delta like non-canonical Notch ligand 1. (399 aa)
ADGRE1Adhesion G protein-coupled receptor E1; Belongs to the G-protein coupled receptor 2 family. (796 aa)
F12Coagulation factor XII. (615 aa)
CNTNAP5Contactin associated protein like 5. (1305 aa)
DLL3Delta like canonical Notch ligand 3. (618 aa)
NOTCH4Notch receptor 4. (1997 aa)
NID2Nidogen 2. (1376 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa)
AREL1Uncharacterized protein. (1827 aa)
NRG3Neuregulin 3. (696 aa)
STAB1Stabilin 1. (2575 aa)
NELL2Protein kinase C-binding protein NELL2 isoform a. (816 aa)
KLHL22Uncharacterized protein. (870 aa)
EGFLAMEGF-like, fibronectin type-III and laminin G-like domain-containing protein. (1017 aa)
NOTCH1Notch receptor 1. (2556 aa)
WIF1WNT inhibitory factor 1. (445 aa)
PTGS2Prostaglandin-endoperoxide synthase 2. (604 aa)
THBDUncharacterized protein. (607 aa)
CD93Complement component C1q receptor. (651 aa)
CUBNCubilin. (3624 aa)
CD248C-type lectin domain-containing protein. (757 aa)
MEGF9Multiple EGF like domains 9. (599 aa)
TLL2Metalloendopeptidase. (1015 aa)
CNTNAP2Contactin associated protein like 2. (1331 aa)
CELSR2Cadherin EGF LAG seven-pass G-type receptor 2; Belongs to the G-protein coupled receptor 2 family. (2926 aa)
VLDLRVery low density lipoprotein receptor. (947 aa)
LAMC1Laminin subunit gamma-1. (1608 aa)
CELSR3Cadherin EGF LAG seven-pass G-type receptor 3; Belongs to the G-protein coupled receptor 2 family. (3312 aa)
MUC13Mucin 13, cell surface associated. (495 aa)
NRXN3Neurexin 3. (1571 aa)
NOTCH3Notch receptor 3. (2321 aa)
BMP1Metalloendopeptidase. (986 aa)
MASP1Mannan binding lectin serine peptidase 1; Belongs to the peptidase S1 family. (753 aa)
PTGS1Prostaglandin-endoperoxide synthase 1. (599 aa)
NID1Nidogen-1. (1247 aa)
CRB1Crumbs cell polarity complex component 1. (1406 aa)
PCSK6Proprotein convertase subtilisin/kexin type 6; Belongs to the peptidase S8 family. (966 aa)
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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