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KCNA5 KCNA5 KCNH2 KCNH2 SCN11A SCN11A KCNQ4 KCNQ4 SCN3A SCN3A KCNV1 KCNV1 KCNA3 KCNA3 KCNA2 KCNA2 SCN7A SCN7A KCNMA1 KCNMA1 CACNA1S CACNA1S KCNS3 KCNS3 CNGA4 CNGA4 HCN4 HCN4 TRPV6 TRPV6 NALCN NALCN SCN10A SCN10A SCN5A SCN5A TRPV2 TRPV2 KCNQ5 KCNQ5 CACNA1E CACNA1E KCNB2 KCNB2 KCNS1 KCNS1 TRPM6 TRPM6 CACNA1C CACNA1C HCN2 HCN2 TRPC1 TRPC1 SCN4A SCN4A KCNH3 KCNH3 KCNG4 KCNG4 TRPC5 TRPC5 CACNA1B CACNA1B KCNQ3 KCNQ3 CACNA1F CACNA1F TRPV5 TRPV5 KCNQ1 KCNQ1 KCNB1 KCNB1 KCNH4 KCNH4 KCNC1 KCNC1 TRPM3 TRPM3 CATSPER3 CATSPER3 KCNH6 KCNH6 CATSPER4 CATSPER4 SCN8A SCN8A TRPC7 TRPC7 KCNU1 KCNU1 KCNG2 KCNG2 ITPR3 ITPR3 TRPV3 TRPV3 TRPC4 TRPC4 TRPM1 TRPM1 KCNH8 KCNH8 RYR1 RYR1 CACNA1A CACNA1A TRPM2 TRPM2 TPCN1 TPCN1 KCND1 KCND1 TRPM5 TRPM5 ITPR1 ITPR1 TRPM8 TRPM8 TRPA1 TRPA1 TRPC6 TRPC6 CACNA1D CACNA1D CNGA1 CNGA1 SCN1A SCN1A TRPM4 TRPM4 RYR3 RYR3 CACNA1H CACNA1H TRPV4 TRPV4 KCND3 KCND3 KCNH1 KCNH1 HVCN1 HVCN1 CNGA2 CNGA2 KCNA1 KCNA1 KCNH7 KCNH7 KCNS2 KCNS2 KCNG1 KCNG1 RYR2 RYR2 CATSPER2 CATSPER2 SCN2A SCN2A CNGA3 CNGA3 CACNA1I CACNA1I KCNC2 KCNC2 KCNA10 KCNA10 ITPR2 ITPR2 TRPV1 TRPV1 CACNA1G CACNA1G TRPC3 TRPC3 KCNC3 KCNC3 KCNH5 KCNH5 HCN1 HCN1 HCN3 HCN3 CATSPER1 CATSPER1 KCNA6 KCNA6 KCNV2 KCNV2 KCNG3 KCNG3 KCNA7 KCNA7 KCNA4 KCNA4 KCNC4 KCNC4 TPCN2 TPCN2 KCND2 KCND2
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
KCNA5Potassium voltage-gated channel subfamily A member 5; Belongs to the potassium channel family. (605 aa)
KCNH2Potassium voltage-gated channel subfamily H member 2. (1159 aa)
SCN11ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1790 aa)
KCNQ4Potassium voltage-gated channel subfamily Q member 4; Belongs to the potassium channel family. (695 aa)
SCN3ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2000 aa)
KCNV1Potassium voltage-gated channel modifier subfamily V member 1; Belongs to the potassium channel family. (500 aa)
KCNA3Potassium voltage-gated channel subfamily A member 3; Belongs to the potassium channel family. (575 aa)
KCNA2Potassium voltage-gated channel subfamily A member 2 isoform a; Belongs to the potassium channel family. (499 aa)
SCN7ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1977 aa)
KCNMA1Calcium-activated potassium channel subunit alpha-1; Potassium channel activated by both membrane depolarization or increase in cytosolic Ca(2+) that mediates export of K(+). It is also activated by the concentration of cytosolic Mg(2+). Its activation dampens the excitatory events that elevate the cytosolic Ca(2+) concentration and/or depolarize the cell membrane. It therefore contributes to repolarization of the membrane potential. Plays a key role in controlling excitability in a number of systems, such as regulation of the contraction of smooth muscle, the tuning of hair cells in t [...] (1233 aa)
CACNA1SVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1873 aa)
KCNS3Potassium voltage-gated channel modifier subfamily S member 3; Belongs to the potassium channel family. (491 aa)
CNGA4Cyclic nucleotide gated channel subunit alpha 4. (575 aa)
HCN4Hyperpolarization activated cyclic nucleotide gated potassium channel 4. (1203 aa)
TRPV6Transient receptor potential cation channel subfamily V member 6; Belongs to the transient receptor (TC 1.A.4) family. (821 aa)
NALCNSodium leak channel non-selective protein. (1738 aa)
SCN10ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1956 aa)
SCN5ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2017 aa)
TRPV2Transient receptor potential cation channel subfamily V member 2; Belongs to the transient receptor (TC 1.A.4) family. (764 aa)
KCNQ5Potassium voltage-gated channel subfamily Q member 5. (951 aa)
CACNA1EVoltage-dependent R-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1E gives rise to R-type calcium currents. (2412 aa)
KCNB2Potassium voltage-gated channel subfamily B member 2; Belongs to the potassium channel family. (910 aa)
KCNS1Potassium voltage-gated channel subfamily S member 1; Potassium channel subunit that does not form functional channels by itself. Can form functional heterotetrameric channels with KCNB1 and KCNB2; modulates the delayed rectifier voltage-gated potassium channel activation and deactivation rates of KCNB1 and KCNB2. Belongs to the potassium channel family. S (TC 1.A.1.2) subfamily. Kv9.1/KCNS1 sub-subfamily. (529 aa)
TRPM6Transient receptor potential cation channel subfamily M member 6. (2025 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2186 aa)
HCN2Hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2. (888 aa)
TRPC1Transient receptor potential cation channel subfamily C member 1; Belongs to the transient receptor (TC 1.A.4) family. (834 aa)
SCN4ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1836 aa)
KCNH3Potassium voltage-gated channel subfamily H member 3. (1083 aa)
KCNG4Potassium voltage-gated channel modifier subfamily G member 4; Belongs to the potassium channel family. (519 aa)
TRPC5Transient receptor potential cation channel subfamily C member 5; Belongs to the transient receptor (TC 1.A.4) family. (974 aa)
CACNA1BVoltage-dependent N-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1B gives rise to N-type calcium currents. (2338 aa)
KCNQ3Potassium voltage-gated channel subfamily KQT member 3 isoform 1; Belongs to the potassium channel family. (872 aa)
CACNA1FVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1970 aa)
TRPV5Transient receptor potential cation channel subfamily V member 5; Belongs to the transient receptor (TC 1.A.4) family. (729 aa)
KCNQ1Potassium voltage-gated channel subfamily Q member 1; Belongs to the potassium channel family. (676 aa)
KCNB1Potassium voltage-gated channel subfamily B member 1; Belongs to the potassium channel family. (858 aa)
KCNH4Potassium voltage-gated channel subfamily H member 4. (1017 aa)
KCNC1BTB domain-containing protein; Belongs to the potassium channel family. (585 aa)
TRPM3Transient receptor potential cation channel subfamily M member 3. (1707 aa)
CATSPER3Cation channel sperm associated 3. (398 aa)
KCNH6Potassium voltage-gated channel subfamily H member 6. (994 aa)
CATSPER4Cation channel sperm associated 4. (472 aa)
SCN8ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1980 aa)
TRPC7Transient receptor potential cation channel subfamily C member 7; Belongs to the transient receptor (TC 1.A.4) family. (862 aa)
KCNU1Potassium calcium-activated channel subfamily U member 1. (1149 aa)
KCNG2Potassium voltage-gated channel modifier subfamily G member 2; Belongs to the potassium channel family. (467 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2671 aa)
TRPV3Transient receptor potential cation channel subfamily V member 3; Belongs to the transient receptor (TC 1.A.4) family. (790 aa)
TRPC4ANK_REP_REGION domain-containing protein; Belongs to the transient receptor (TC 1.A.4) family. (977 aa)
TRPM1Transient receptor potential cation channel subfamily M member 1. (1642 aa)
KCNH8Potassium voltage-gated channel subfamily H member 8. (1107 aa)
RYR1Ryanodine receptor 1. (4928 aa)
CACNA1AVoltage-dependent P/Q-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q- type calcium currents. (2411 aa)
TRPM2Transient receptor potential cation channel subfamily M member 2. (1539 aa)
TPCN1Two pore segment channel 1. (888 aa)
KCND1Potassium voltage-gated channel subfamily D member 1; Belongs to the potassium channel family. (647 aa)
TRPM5Transient receptor potential cation channel subfamily M member 5. (1156 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1 isoform 3. (2758 aa)
TRPM8Transient receptor potential cation channel subfamily M member 8. (1104 aa)
TRPA1Transient receptor potential cation channel subfamily A member 1; Belongs to the transient receptor (TC 1.A.4) family. (1144 aa)
TRPC6Transient receptor potential cation channel subfamily C member 6; Belongs to the transient receptor (TC 1.A.4) family. (931 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2181 aa)
CNGA1Cyclic nucleotide gated channel subunit alpha 1. (759 aa)
SCN1ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2008 aa)
TRPM4Transient receptor potential cation channel subfamily M member 4. (1215 aa)
RYR3Ryanodine receptor 3. (4870 aa)
CACNA1HCalcium voltage-gated channel subunit alpha1 H. (2352 aa)
TRPV4Transient receptor potential cation channel subfamily V member 4; Belongs to the transient receptor (TC 1.A.4) family. (963 aa)
KCND3BTB domain-containing protein; Belongs to the potassium channel family. (655 aa)
KCNH1Potassium voltage-gated channel subfamily H member 1 isoform 2. (962 aa)
HVCN1Hydrogen voltage gated channel 1. (273 aa)
CNGA2Cyclic nucleotide gated channel subunit alpha 2. (664 aa)
KCNA1Voltage-gated potassium channel subunit Kv1.1; Belongs to the potassium channel family. (495 aa)
KCNH7Potassium voltage-gated channel subfamily H member 7. (1529 aa)
KCNS2Uncharacterized protein; Belongs to the potassium channel family. (477 aa)
KCNG1Potassium voltage-gated channel modifier subfamily G member 1; Belongs to the potassium channel family. (513 aa)
RYR2Ryanodine receptor 2. (4967 aa)
CATSPER2Cation channel sperm-associated protein 2 isoform 4. (199 aa)
SCN2ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2005 aa)
CNGA3Cyclic nucleotide gated channel subunit alpha 3. (694 aa)
CACNA1IVoltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2111 aa)
KCNC2Potassium voltage-gated channel subfamily C member 2 isoform KV3.2b; Belongs to the potassium channel family. (638 aa)
KCNA10Potassium voltage-gated channel subfamily A member 10; Belongs to the potassium channel family. (511 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2700 aa)
TRPV1Transient receptor potential cation channel subfamily V member 1; Belongs to the transient receptor (TC 1.A.4) family. (839 aa)
CACNA1GVoltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2377 aa)
TRPC3Transient receptor potential cation channel subfamily C member 3; Belongs to the transient receptor (TC 1.A.4) family. (921 aa)
KCNC3Potassium voltage-gated channel subfamily C member 3; Belongs to the potassium channel family. (757 aa)
KCNH5Potassium voltage-gated channel subfamily H member 5. (988 aa)
HCN1Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1. (885 aa)
HCN3Hyperpolarization activated cyclic nucleotide gated potassium channel 3. (777 aa)
CATSPER1Cation channel sperm associated 1. (798 aa)
KCNA6BTB domain-containing protein; Belongs to the potassium channel family. (530 aa)
KCNV2Uncharacterized protein; Belongs to the potassium channel family. (545 aa)
KCNG3Potassium voltage-gated channel subfamily G member 3 isoform 2; Belongs to the potassium channel family. (425 aa)
KCNA7Potassium voltage-gated channel subfamily A member 7; Belongs to the potassium channel family. (569 aa)
KCNA4Voltage-gated potassium channel subunit Kv1.4; Belongs to the potassium channel family. (652 aa)
KCNC4Potassium voltage-gated channel subfamily C member 4; Belongs to the potassium channel family. (632 aa)
TPCN2Two pore segment channel 2. (823 aa)
KCND2Potassium voltage-gated channel subfamily D member 2; Belongs to the potassium channel family. (630 aa)
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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