(46 nodes) Cyclin-like superfamily network (Macaca mulatta)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CCND1	Uncharacterized protein; Belongs to the cyclin family. (303 aa)
	CNTD2	Cyclin N-terminal domain containing 2; Belongs to the cyclin family. (304 aa)
	LOC700258	CYCLIN domain-containing protein. (360 aa)
	CABLES2	Cdk5 and Abl enzyme substrate 2. (481 aa)
	CABLES1	Cdk5 and Abl enzyme substrate 1. (629 aa)
	CCNY	CYCLIN domain-containing protein; Belongs to the cyclin family. (350 aa)
	CDK5R1	Cyclin-dependent kinase 5 activator. (307 aa)
	CCNA2	Cyclin-A2; Belongs to the cyclin family. (432 aa)
	CCNI2	Cyclin I family member 2; Belongs to the cyclin family. (386 aa)
	CCNO	Cyclin O; Belongs to the cyclin family. (644 aa)
	CCNL1	Cyclin-L1; Belongs to the cyclin family. (526 aa)
	CCNQ	Cyclin-related protein FAM58A isoform 2; Belongs to the cyclin family. (228 aa)
	LOC704495	Cyclin N-terminal domain-containing protein. (356 aa)
	CNTD1	Cyclin N-terminal domain containing 1. (329 aa)
	RBL1	RB transcriptional corepressor like 1. (1025 aa)
	CCNG1	Cyclin G1; Belongs to the cyclin family. (295 aa)
	CCNE1	Cyclin E1; Belongs to the cyclin family. (410 aa)
	CCNE2	Cyclin E2; Belongs to the cyclin family. (426 aa)
	BRF1	Transcription factor IIIB 90 kDa subunit isoform 1. (677 aa)
	CCNB1	G2/mitotic-specific cyclin-B1; Belongs to the cyclin family. (433 aa)
	CCNT2	Cyclin T2; Belongs to the cyclin family. (709 aa)
	CDK5R2	Cyclin-dependent kinase 5 activator. (367 aa)
	CCNYL1	Cyclin Y like 1; Belongs to the cyclin family. (359 aa)
	CCNC	Cyclin C; Belongs to the cyclin family. (282 aa)
	BRF2	BRF2 RNA polymerase III transcription initiation factor subunit. (419 aa)
	CCNA1	Cyclin-A1 isoform a; Belongs to the cyclin family. (465 aa)
	CCNJL	Cyclin J like; Belongs to the cyclin family. (489 aa)
	CCND3	Cyclin D3; Belongs to the cyclin family. (315 aa)
	RBL2	RB transcriptional corepressor like 2. (1141 aa)
	RB1	Retinoblastoma-associated protein. (928 aa)
	CCNL2	Uncharacterized protein; Belongs to the cyclin family. (546 aa)
	CCNH	Cyclin H; Belongs to the cyclin family. (331 aa)
	CCNB3	Cyclin B3; Belongs to the cyclin family. (1362 aa)
	CCNB2	Cyclin B2; Belongs to the cyclin family. (398 aa)
	CCNK	Cyclin K; Belongs to the cyclin family. (580 aa)
	CCNI	Cyclin I; Belongs to the cyclin family. (384 aa)
	CCNJ	Cyclin J; Belongs to the cyclin family. (533 aa)
	LOC715684	Cyclin N-terminal domain-containing protein. (401 aa)
	CCNYL3	Cyclin N-terminal domain-containing protein. (447 aa)
	CASD1	CAS1 domain containing 1. (935 aa)
	CCNT1	Cyclin T1; Belongs to the cyclin family. (728 aa)
	CCNG2	Cyclin G2; Belongs to the cyclin family. (384 aa)
	GTF2B	General transcription factor IIB. (312 aa)
	LOC701413	Uncharacterized protein; Belongs to the cyclin family. (465 aa)
	LOC114674380	Cyclin N-terminal domain-containing protein. (400 aa)
	CCNF	Cyclin F; Belongs to the cyclin family. (786 aa)

Your Current Organism:

Macaca mulatta

NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BRF1	BRF2	ENSMMUP00000032516	ENSMMUP00000041806	Transcription factor IIIB 90 kDa subunit isoform 1.	BRF2 RNA polymerase III transcription initiation factor subunit.	0.582
BRF1	GTF2B	ENSMMUP00000032516	ENSMMUP00000074593	Transcription factor IIIB 90 kDa subunit isoform 1.	General transcription factor IIB.	0.560
BRF2	BRF1	ENSMMUP00000041806	ENSMMUP00000032516	BRF2 RNA polymerase III transcription initiation factor subunit.	Transcription factor IIIB 90 kDa subunit isoform 1.	0.582
BRF2	GTF2B	ENSMMUP00000041806	ENSMMUP00000074593	BRF2 RNA polymerase III transcription initiation factor subunit.	General transcription factor IIB.	0.463
CABLES1	CCNA1	ENSMMUP00000006791	ENSMMUP00000042053	Cdk5 and Abl enzyme substrate 1.	Cyclin-A1 isoform a; Belongs to the cyclin family.	0.562
CABLES1	CCNA2	ENSMMUP00000006791	ENSMMUP00000012854	Cdk5 and Abl enzyme substrate 1.	Cyclin-A2; Belongs to the cyclin family.	0.486
CABLES1	CCNE1	ENSMMUP00000006791	ENSMMUP00000027198	Cdk5 and Abl enzyme substrate 1.	Cyclin E1; Belongs to the cyclin family.	0.474
CABLES1	CCNE2	ENSMMUP00000006791	ENSMMUP00000032048	Cdk5 and Abl enzyme substrate 1.	Cyclin E2; Belongs to the cyclin family.	0.467
CABLES2	CCNA1	ENSMMUP00000006636	ENSMMUP00000042053	Cdk5 and Abl enzyme substrate 2.	Cyclin-A1 isoform a; Belongs to the cyclin family.	0.458
CABLES2	CCNA2	ENSMMUP00000006636	ENSMMUP00000012854	Cdk5 and Abl enzyme substrate 2.	Cyclin-A2; Belongs to the cyclin family.	0.458
CABLES2	CCNE1	ENSMMUP00000006636	ENSMMUP00000027198	Cdk5 and Abl enzyme substrate 2.	Cyclin E1; Belongs to the cyclin family.	0.469
CABLES2	CCNE2	ENSMMUP00000006636	ENSMMUP00000032048	Cdk5 and Abl enzyme substrate 2.	Cyclin E2; Belongs to the cyclin family.	0.467
CCNA1	CABLES1	ENSMMUP00000042053	ENSMMUP00000006791	Cyclin-A1 isoform a; Belongs to the cyclin family.	Cdk5 and Abl enzyme substrate 1.	0.562
CCNA1	CABLES2	ENSMMUP00000042053	ENSMMUP00000006636	Cyclin-A1 isoform a; Belongs to the cyclin family.	Cdk5 and Abl enzyme substrate 2.	0.458
CCNA1	CCNA2	ENSMMUP00000042053	ENSMMUP00000012854	Cyclin-A1 isoform a; Belongs to the cyclin family.	Cyclin-A2; Belongs to the cyclin family.	0.958
CCNA1	CCNB1	ENSMMUP00000042053	ENSMMUP00000034570	Cyclin-A1 isoform a; Belongs to the cyclin family.	G2/mitotic-specific cyclin-B1; Belongs to the cyclin family.	0.782
CCNA1	CCNB2	ENSMMUP00000042053	ENSMMUP00000058464	Cyclin-A1 isoform a; Belongs to the cyclin family.	Cyclin B2; Belongs to the cyclin family.	0.758
CCNA1	CCNB3	ENSMMUP00000042053	ENSMMUP00000057595	Cyclin-A1 isoform a; Belongs to the cyclin family.	Cyclin B3; Belongs to the cyclin family.	0.722
CCNA1	CCNC	ENSMMUP00000042053	ENSMMUP00000041679	Cyclin-A1 isoform a; Belongs to the cyclin family.	Cyclin C; Belongs to the cyclin family.	0.547
CCNA1	CCND1	ENSMMUP00000042053	ENSMMUP00000080080	Cyclin-A1 isoform a; Belongs to the cyclin family.	Uncharacterized protein; Belongs to the cyclin family.	0.514