STRINGSTRING
LMNB1 LMNB1 NEDD8 NEDD8 LOC114669830 LOC114669830 TPRX1 TPRX1 H2BC5 H2BC5 LOC710748 LOC710748 RAD50 RAD50 HIST1H2AC HIST1H2AC RBBP8 RBBP8 SYCE1 SYCE1 LOC106996511 LOC106996511 H2AFZ H2AFZ SUN3 SUN3 STAG1 STAG1 H2AFX H2AFX RPA1 RPA1 FAM9C FAM9C CATSPER4 CATSPER4 LOC699317 LOC699317 LMNA LMNA KCNT2 KCNT2 BRCA1 BRCA1 F6PS34_MACMU F6PS34_MACMU F7C6W4_MACMU F7C6W4_MACMU MSH5 MSH5 RAD51 RAD51 LOC714001 LOC714001 CATSPERB CATSPERB NBN NBN IZUMO4 IZUMO4 TMEM238 TMEM238 CDK4 CDK4 MLH1 MLH1 ADAM18 ADAM18 HIST1H2BA HIST1H2BA F7DM39_MACMU F7DM39_MACMU SPAG4 SPAG4 POT1 POT1 BLM BLM DIDO1 DIDO1 SYNE1 SYNE1 FAM9B FAM9B STAG3 STAG3 H2AFJ H2AFJ SYCP1 SYCP1 IZUMO2 IZUMO2 ZP2 ZP2 TERF2 TERF2 LOC699443 LOC699443 CATSPERG CATSPERG TOP3A TOP3A REC8 REC8 ADAM21 ADAM21 PSMC3IP PSMC3IP ACD ACD H2AFB3 H2AFB3 SUN5 SUN5 ADAM2 ADAM2 SMC1A SMC1A RAD51C RAD51C SMC3 SMC3 ATR ATR SYCP2L SYCP2L SUN2 SUN2 BRCA2 BRCA2 TERF2IP TERF2IP ZP1 ZP1 KCNU1 KCNU1 ADAM20 ADAM20 SPO11 SPO11 RPA3 RPA3 MSH4 MSH4 LOC695427-2 LOC695427-2 H2BU1 H2BU1 H2AC20 H2AC20 CATSPER2 CATSPER2 ZP4 ZP4 HIST1H2BJ HIST1H2BJ ZP3 ZP3 IZUMO1 IZUMO1 GPR83 GPR83 ATM ATM CD9 CD9 CATSPER3 CATSPER3 ACR ACR SPAM1 SPAM1 TEX12 TEX12 H2BC15 H2BC15 LOC695427 LOC695427 ADAM29 ADAM29 H2AFV H2AFV HIST1H2BK HIST1H2BK SYCP3 SYCP3 CATSPER1 CATSPER1 HIST1H2BO HIST1H2BO LOC697721 LOC697721 LOC100430668 LOC100430668 SMC1B SMC1B RAD21 RAD21 ENSMMUP00000075093 ENSMMUP00000075093 LOC699110 LOC699110 FKBP6 FKBP6 LOC695323 LOC695323 SUN1 SUN1 OVGP1 OVGP1 LOC708899 LOC708899 LOC693887 LOC693887 LOC703889 LOC703889 B4GALT1 B4GALT1 LOC704341 LOC704341 LOC106996511-6 LOC106996511-6 ENSMMUP00000069269 ENSMMUP00000069269 LOC698354 LOC698354 LOC718280 LOC718280 LOC106996511-5 LOC106996511-5 IZUMO3 IZUMO3 ENSMMUP00000068277 ENSMMUP00000068277 LOC693939 LOC693939 SYNE2 SYNE2 FAM9A FAM9A ENSMMUP00000067674 ENSMMUP00000067674 ADAM30 ADAM30 SYCE3 SYCE3 LOC698105 LOC698105 ENSMMUP00000066392 ENSMMUP00000066392 LOC696808-3 LOC696808-3 TEX15 TEX15 LOC696808-2 LOC696808-2 LOC106996511-4 LOC106996511-4 UBE2I UBE2I LOC697115 LOC697115 LOC106996511-3 LOC106996511-3 STAG2 STAG2 H3-4 H3-4 MLH3 MLH3 LOC696808 LOC696808 H3C8 H3C8 HVCN1 HVCN1 LOC106996511-2 LOC106996511-2 HIST1H3D HIST1H3D LOC704104 LOC704104 LOC703593 LOC703593 LOC106995531 LOC106995531 LOC696506 LOC696506 H2BE1 H2BE1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LMNB1Lamin-B1 isoform 1; Belongs to the intermediate filament family. (586 aa)
NEDD8TERF1 interacting nuclear factor 2. (482 aa)
LOC114669830Histone H3; Belongs to the histone H3 family. (136 aa)
TPRX1Tetrapeptide repeat homeobox 1. (458 aa)
H2BC5Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC710748Histone H3; Belongs to the histone H3 family. (136 aa)
RAD50Zinc-hook domain-containing protein. (1411 aa)
HIST1H2ACHistone H2A; Belongs to the histone H2A family. (130 aa)
RBBP8Uncharacterized protein. (898 aa)
SYCE1Uncharacterized protein. (331 aa)
LOC106996511Histone H4. (103 aa)
H2AFZHistone H2A; Belongs to the histone H2A family. (128 aa)
SUN3Sad1 and UNC84 domain containing 3. (361 aa)
STAG1Cohesin subunit SA-1. (1258 aa)
H2AFXHistone H2A; Belongs to the histone H2A family. (143 aa)
RPA1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (616 aa)
FAM9CFamily with sequence similarity 9 member C. (176 aa)
CATSPER4Cation channel sperm associated 4. (472 aa)
LOC699317Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
LMNAPrelamin-A/C isoform 1; Belongs to the intermediate filament family. (663 aa)
KCNT2Potassium sodium-activated channel subfamily T member 2. (1135 aa)
BRCA1Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] (1884 aa)
F6PS34_MACMUHistone H2A; Belongs to the histone H2A family. (169 aa)
F7C6W4_MACMUHistone H2A; Belongs to the histone H2A family. (166 aa)
MSH5DNA_MISMATCH_REPAIR_2 domain-containing protein. (834 aa)
RAD51RAD51 recombinase; Belongs to the RecA family. (380 aa)
LOC714001Histone H2B; Belongs to the histone H2B family. (126 aa)
CATSPERBCation channel sperm associated auxiliary subunit beta. (1111 aa)
NBNNibrin; Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double- strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis. (754 aa)
IZUMO4IZUMO family member 4. (219 aa)
TMEM238Transmembrane protein 238. (175 aa)
CDK4Cyclin-dependent kinase 4; Belongs to the protein kinase superfamily. (303 aa)
MLH1MutL homolog 1. (756 aa)
ADAM18ADAM metallopeptidase domain 18. (739 aa)
HIST1H2BAHistone H2B; Belongs to the histone H2B family. (127 aa)
F7DM39_MACMUUncharacterized protein. (143 aa)
SPAG4Sperm associated antigen 4. (437 aa)
POT1Protection of telomeres 1. (658 aa)
BLMBLM RecQ like helicase. (1416 aa)
DIDO1Death inducer-obliterator 1. (2238 aa)
SYNE1Spectrin repeat containing nuclear envelope protein 1. (8797 aa)
FAM9BFamily with sequence similarity 9 member B. (186 aa)
STAG3SCD domain-containing protein. (1342 aa)
H2AFJHistone H2A; Belongs to the histone H2A family. (129 aa)
SYCP1Synaptonemal complex protein 1. (976 aa)
IZUMO2Uncharacterized protein. (221 aa)
ZP2Zona pellucida glycoprotein 2. (745 aa)
TERF2Telomeric repeat binding factor 2. (542 aa)
LOC699443Histone H3; Belongs to the histone H3 family. (136 aa)
CATSPERGCation channel sperm associated auxiliary subunit gamma. (1159 aa)
TOP3ADNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (1001 aa)
REC8REC8 meiotic recombination protein. (565 aa)
ADAM21Uncharacterized protein. (722 aa)
PSMC3IPPSMC3 interacting protein. (234 aa)
ACDACD shelterin complex subunit and telomerase recruitment factor. (455 aa)
H2AFB3Histone H2A; Belongs to the histone H2A family. (115 aa)
SUN5Sad1 and UNC84 domain containing 5. (376 aa)
ADAM2ADAM metallopeptidase domain 2. (735 aa)
SMC1AStructural maintenance of chromosomes protein. (1233 aa)
RAD51CRAD51 paralog C. (367 aa)
SMC3Structural maintenance of chromosomes protein. (1196 aa)
ATRATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2644 aa)
SYCP2LSynaptonemal complex protein 2 like. (787 aa)
SUN2Sad1 and UNC84 domain containing 2. (800 aa)
BRCA2BRCA2 DNA repair associated. (3377 aa)
TERF2IPTelomeric repeat-binding factor 2-interacting protein 1. (400 aa)
ZP1Zona pellucida glycoprotein 1. (640 aa)
KCNU1Potassium calcium-activated channel subfamily U member 1. (1149 aa)
ADAM20ADAM metallopeptidase domain 20. (838 aa)
SPO11SPO11 initiator of meiotic double stranded breaks. (396 aa)
RPA3Replication protein A 14 kDa subunit. (121 aa)
MSH4MutS homolog 4. (935 aa)
LOC695427-2Histone H3; Belongs to the histone H3 family. (136 aa)
H2BU1Histone H2B; Belongs to the histone H2B family. (126 aa)
H2AC20Histone H2A; Belongs to the histone H2A family. (129 aa)
CATSPER2Cation channel sperm-associated protein 2 isoform 4. (199 aa)
ZP4Zona pellucida glycoprotein 4. (538 aa)
HIST1H2BJHistone H2B; Belongs to the histone H2B family. (126 aa)
ZP3ZP domain-containing protein. (424 aa)
IZUMO1Izumo-Ig domain-containing protein. (350 aa)
GPR83Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (778 aa)
ATMSerine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3056 aa)
CD9Tetraspanin. (228 aa)
CATSPER3Cation channel sperm associated 3. (398 aa)
ACRAcrosin; Acrosin is the major protease of mammalian spermatozoa. It is a serine protease of trypsin-like cleavage specificity, it is synthesized in a zymogen form, proacrosin and stored in the acrosome. (419 aa)
SPAM1Hyaluronidase. (512 aa)
TEX12Testis-expressed sequence 12 protein. (123 aa)
H2BC15Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC695427Histone H3.1. (136 aa)
ADAM29ADAM metallopeptidase domain 29. (845 aa)
H2AFVHistone H2A; Belongs to the histone H2A family. (138 aa)
HIST1H2BKHistone H2B; Belongs to the histone H2B family. (126 aa)
SYCP3Synaptonemal complex protein 3. (236 aa)
CATSPER1Cation channel sperm associated 1. (798 aa)
HIST1H2BOHistone H2B; Belongs to the histone H2B family. (126 aa)
LOC697721Histone H4. (103 aa)
LOC100430668Histone H3.1. (136 aa)
SMC1BStructural maintenance of chromosomes protein. (1243 aa)
RAD21Double-strand-break repair protein rad21 homolog. (631 aa)
ENSMMUP00000075093Peptidase M12B domain-containing protein. (107 aa)
LOC699110Histone H4. (103 aa)
FKBP6Peptidylprolyl isomerase. (396 aa)
LOC695323Histone H4. (103 aa)
SUN1Sad1 and UNC84 domain containing 1. (1065 aa)
OVGP1Glyco_18 domain-containing protein; Belongs to the glycosyl hydrolase 18 family. (662 aa)
LOC708899Histone H3.3. (136 aa)
LOC693887Histone H3.3. (136 aa)
LOC703889Histone H3.1. (136 aa)
B4GALT1Beta-1,4-galactosyltransferase 1. (398 aa)
LOC704341Histone H4. (103 aa)
LOC106996511-6Histone H4. (103 aa)
ENSMMUP00000069269Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (437 aa)
LOC698354Histone H4. (103 aa)
LOC718280Histone domain-containing protein. (136 aa)
LOC106996511-5Histone H4. (103 aa)
IZUMO3IZUMO family member 3. (292 aa)
ENSMMUP00000068277Histone H3; Belongs to the histone H3 family. (136 aa)
LOC693939Histone H3; Belongs to the histone H3 family. (136 aa)
SYNE2Spectrin repeat containing nuclear envelope protein 2. (6909 aa)
FAM9AFamily with sequence similarity 9 member A. (213 aa)
ENSMMUP00000067674Uncharacterized protein. (87 aa)
ADAM30ADAM metallopeptidase domain 30. (809 aa)
SYCE3Synaptonemal complex central element protein 3. (88 aa)
LOC698105Histone H3.1. (136 aa)
ENSMMUP00000066392annotation not available (136 aa)
LOC696808-3Histone H2B type 1. (126 aa)
TEX15Testis expressed 15, meiosis and synapsis associated. (3155 aa)
LOC696808-2Histone H2B type 1. (126 aa)
LOC106996511-4Histone H4. (103 aa)
UBE2IUBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (260 aa)
LOC697115Histone H4. (103 aa)
LOC106996511-3Histone H4. (103 aa)
STAG2Cohesin subunit SA-2 isoform a. (1268 aa)
H3-4Histone H3; Belongs to the histone H3 family. (136 aa)
MLH3Uncharacterized protein. (1505 aa)
LOC696808Histone H2B type 1. (126 aa)
H3C8H3 clustered histone 8. (136 aa)
HVCN1Hydrogen voltage gated channel 1. (273 aa)
LOC106996511-2Histone H4. (103 aa)
HIST1H3DHistone cluster 1, H3d. (136 aa)
LOC704104Histone domain-containing protein. (154 aa)
LOC703593Uncharacterized protein. (348 aa)
LOC106995531Histone H2A-Bbd type 2/3-like. (115 aa)
LOC696506Histone H2B; Belongs to the histone H2B family. (126 aa)
H2BE1Histone H2B; Belongs to the histone H2B family. (122 aa)
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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