STRINGSTRING
NCK1 NCK1 PSMC6 PSMC6 PSMC5 PSMC5 CD3E CD3E TRBV5-1 TRBV5-1 TRBV12-5 TRBV12-5 ENSMMUP00000061439 ENSMMUP00000061439 CARD11 CARD11 EVL EVL LAT LAT PSMA3 PSMA3 CD247 CD247 LCP2 LCP2 PLCG1 PLCG1 PSMD8 PSMD8 RELA RELA WAS WAS PGBD4 PGBD4 SKP1-2 SKP1-2 NFKBIA NFKBIA PTPRC PTPRC CD3G CD3G PTPN22 PTPN22 PSMA2 PSMA2 PSME3 PSME3 TRAV39 TRAV39 PSMD14 PSMD14 TRBV6-1 TRBV6-1 UBE2N UBE2N PSME2 PSME2 HLA-DRA HLA-DRA CCDC71L CCDC71L UBB UBB BTRC BTRC FBXW11 FBXW11 PSMA6 PSMA6 PSMB3 PSMB3 UBC UBC LCK LCK CHUK CHUK KXD1 KXD1 PSMA8 PSMA8 PSMD10 PSMD10 IKBKG IKBKG PSMD6 PSMD6 F7HHF9_MACMU F7HHF9_MACMU NFKB1 NFKB1 MAP3K7 MAP3K7 F7ALC4_MACMU F7ALC4_MACMU PSMC1 PSMC1 IKBKB IKBKB RIPK2 RIPK2 CDC34 CDC34 VASP VASP SPNS3 SPNS3 ZAP70 ZAP70 FYB1 FYB1 PSMB4 PSMB4 PRKCQ PRKCQ PSMD3 PSMD3 TRBV4-1 TRBV4-1 PSMB1 PSMB1 CISD1 CISD1 MAMU-DPA MAMU-DPA PAK1 PAK1 PSMA7 PSMA7 TRAF6 TRAF6 CD3D CD3D PSMC4 PSMC4 CD101 CD101 PSMD9 PSMD9 UBA52 UBA52 PSMC3 PSMC3 RPS27A-2 RPS27A-2 TAB2 TAB2 MALT1 MALT1 RPS27A RPS27A PSMB2 PSMB2 PSMB6 PSMB6 PSME1 PSME1 PAK2 PAK2 PSMD1 PSMD1 PIK3R1 PIK3R1 PSMD13 PSMD13 PDPK1 PDPK1 F7B371_MACMU F7B371_MACMU PSMB9 PSMB9 ITK ITK PSMA4 PSMA4 MAP3K20 MAP3K20 INPP5D INPP5D PIK3CB PIK3CB PTEN PTEN PSME4 PSME4 PSMD4 PSMD4 PSMB11 PSMB11 PSMB5 PSMB5 PTPRJ PTPRJ BCL10 BCL10 PLCG2 PLCG2 PSMD2 PSMD2 PSMD12 PSMD12 PSMD5 PSMD5 TRAT1 TRAT1 PIK3R2 PIK3R2 PSMC2 PSMC2 PSMF1 PSMF1 PIK3CA PIK3CA TRBV15 TRBV15 ENSMMUP00000081141 ENSMMUP00000081141 TRBV11-1 TRBV11-1 PSMA5 PSMA5 PAK3 PAK3 TRBV7-9 TRBV7-9 ENSMMUP00000077599 ENSMMUP00000077599 ENSMMUP00000076578 ENSMMUP00000076578 HLA-DRB5 HLA-DRB5 ENSMMUP00000075705 ENSMMUP00000075705 LOC114669810 LOC114669810 PSMD11 PSMD11 TRBV27 TRBV27 LOC699631 LOC699631 PSMB7 PSMB7 ENAH ENAH TRBV29-1 TRBV29-1 ENSMMUP00000071311 ENSMMUP00000071311 PSMA1 PSMA1 CSK CSK ENSMMUP00000070949 ENSMMUP00000070949 TRAV29DV5 TRAV29DV5 ENSMMUP00000070235 ENSMMUP00000070235 PAG1 PAG1 ENSMMUP00000069379 ENSMMUP00000069379 CD4 CD4 TRAC TRAC ENSMMUP00000069031 ENSMMUP00000069031 ENSMMUP00000068848 ENSMMUP00000068848 ENSMMUP00000068350 ENSMMUP00000068350 SPNS1 SPNS1 PSMB10 PSMB10 ENSMMUP00000067421 ENSMMUP00000067421 GRAP2 GRAP2 CUL1 CUL1 ENSMMUP00000065795 ENSMMUP00000065795 TRBV7-4 TRBV7-4 PSMD7 PSMD7 TRAV19 TRAV19 TRBV7-2 TRBV7-2 ENSMMUP00000064061 ENSMMUP00000064061
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NCK1Cytoplasmic protein. (377 aa)
PSMC6AAA domain-containing protein; Belongs to the AAA ATPase family. (410 aa)
PSMC526S protease regulatory subunit 8 isoform 1; Belongs to the AAA ATPase family. (406 aa)
CD3ECD3e molecule. (217 aa)
TRBV5-1T cell receptor beta variable 5-1. (151 aa)
TRBV12-5T cell receptor beta variable 12-5. (170 aa)
ENSMMUP00000061439IGv domain-containing protein. (196 aa)
CARD11Caspase recruitment domain family member 11. (1154 aa)
EVLEnah/Vasp-like. (469 aa)
LATUncharacterized protein. (305 aa)
PSMA3Proteasome subunit alpha type. (267 aa)
CD247CD247 molecule. (224 aa)
LCP2Lymphocyte cytosolic protein 2. (533 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1291 aa)
PSMD8CSN8_PSD8_EIF3K domain-containing protein. (364 aa)
RELARELA proto-oncogene, NF-kB subunit. (544 aa)
WASWASP actin nucleation promoting factor. (503 aa)
PGBD4PiggyBac transposable element derived 4. (583 aa)
SKP1-2Uncharacterized protein; Belongs to the SKP1 family. (163 aa)
NFKBIANF-kappa-B inhibitor alpha. (317 aa)
PTPRCProtein tyrosine phosphatase receptor type C. (1310 aa)
CD3GCD3g molecule. (209 aa)
PTPN22Protein tyrosine phosphatase non-receptor type 22. (813 aa)
PSMA2Proteasome subunit alpha type. (234 aa)
PSME3Proteasome activator subunit 3. (265 aa)
TRAV39T cell receptor alpha variable 39. (135 aa)
PSMD1426S proteasome non-ATPase regulatory subunit 14. (310 aa)
TRBV6-1T cell receptor beta variable 6-1. (157 aa)
UBE2NUBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (210 aa)
PSME2Proteasome activator subunit 2. (248 aa)
HLA-DRAMamu class II histocompatibility antigen, DR alpha chain; Belongs to the MHC class II family. (378 aa)
CCDC71LCoiled-coil domain containing 71 like. (235 aa)
UBBUncharacterized protein. (229 aa)
BTRCUncharacterized protein. (629 aa)
FBXW11Uncharacterized protein. (563 aa)
PSMA6Proteasome subunit alpha type. (246 aa)
PSMB3Proteasome subunit beta. (261 aa)
UBCUncharacterized protein. (270 aa)
LCKTyrosine-protein kinase. (567 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (745 aa)
KXD1KxDL domain-containing protein. (231 aa)
PSMA8Proteasome subunit alpha type. (250 aa)
PSMD10Proteasome 26S subunit, non-ATPase 10. (253 aa)
IKBKGInhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (489 aa)
PSMD6Proteasome 26S subunit, non-ATPase 6. (442 aa)
F7HHF9_MACMUAAA domain-containing protein; Belongs to the AAA ATPase family. (352 aa)
NFKB1Uncharacterized protein. (977 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7. (620 aa)
F7ALC4_MACMUAAA domain-containing protein; Belongs to the AAA ATPase family. (360 aa)
PSMC126S protease regulatory subunit 4; Belongs to the AAA ATPase family. (440 aa)
IKBKBInhibitor of nuclear factor kappa-B kinase subunit beta isoform 1. (756 aa)
RIPK2Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (540 aa)
CDC34Ubiquitin-conjugating enzyme E2 R1; Belongs to the ubiquitin-conjugating enzyme family. (236 aa)
VASPVasodilator stimulated phosphoprotein. (428 aa)
SPNS3Sphingolipid transporter 3 (putative). (512 aa)
ZAP70Tyrosine-protein kinase. (619 aa)
FYB1FYN binding protein 1. (839 aa)
PSMB4Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa)
PRKCQProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (739 aa)
PSMD326S proteasome non-ATPase regulatory subunit 3. (534 aa)
TRBV4-1T cell receptor beta variable 4-1. (174 aa)
PSMB1Proteasome subunit beta. (241 aa)
CISD1UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (210 aa)
MAMU-DPAMHC class II antigen; Belongs to the MHC class II family. (260 aa)
PAK1Non-specific serine/threonine protein kinase. (575 aa)
PSMA7Proteasome subunit alpha type. (248 aa)
TRAF6TNF receptor-associated factor 6; E3 ubiquitin ligase that, together with UBE2N and UBE2V1, mediates the synthesis of 'Lys-63'-linked-polyubiquitin chains conjugated to proteins, such as IKBKG, IRAK1, AKT1 and AKT2. Also mediates ubiquitination of free/unanchored polyubiquitin chain that leads to MAP3K7 activation. Mediates activation of NF-kappa-B and JUN. May be essential for the formation of functional osteoclasts. Seems to also play a role in dendritic cells (DCs) maturation and/or activation. Represses c-Myb-mediated transactivation, in B-lymphocytes. Adapter protein that seems to [...] (522 aa)
CD3DIg_4 domain-containing protein. (171 aa)
PSMC426S protease regulatory subunit 6B isoform 1; Belongs to the AAA ATPase family. (418 aa)
CD101CD101 molecule. (1021 aa)
PSMD926S proteasome non-ATPase regulatory subunit 9. (223 aa)
UBA52Ubiquitin-60S ribosomal protein L40. (128 aa)
PSMC326S protease regulatory subunit 6A; Belongs to the AAA ATPase family. (439 aa)
RPS27A-2Ubiquitin-40S ribosomal protein S27a. (156 aa)
TAB2TGF-beta-activated kinase 1 and MAP3K7-binding protein 2. (693 aa)
MALT1MALT1 paracaspase. (824 aa)
RPS27AUncharacterized protein. (156 aa)
PSMB2Proteasome subunit beta. (201 aa)
PSMB6Proteasome subunit beta. (285 aa)
PSME1Proteasome activator complex subunit 1 isoform 1. (249 aa)
PAK2Non-specific serine/threonine protein kinase. (524 aa)
PSMD126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (953 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
PSMD13Proteasome 26S subunit, non-ATPase 13. (378 aa)
PDPK13-phosphoinositide dependent protein kinase 1. (557 aa)
F7B371_MACMUProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (313 aa)
PSMB9Proteasome subunit beta. (219 aa)
ITKTyrosine-protein kinase. (620 aa)
PSMA4Proteasome subunit alpha type. (300 aa)
MAP3K20Mitogen-activated protein kinase kinase kinase MLT isoform 1. (800 aa)
INPP5DInositol polyphosphate-5-phosphatase D. (1208 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa)
PTENUncharacterized protein. (589 aa)
PSME4Proteasome activator complex subunit 4. (1843 aa)
PSMD4VWFA domain-containing protein. (400 aa)
PSMB11Proteasome subunit beta. (243 aa)
PSMB5Proteasome subunit beta. (263 aa)
PTPRJProtein tyrosine phosphatase receptor type J. (1336 aa)
BCL10BCL10 immune signaling adaptor. (233 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa)
PSMD226S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (908 aa)
PSMD12Proteasome 26S subunit, non-ATPase 12. (476 aa)
PSMD526S proteasome non-ATPase regulatory subunit 5. (504 aa)
TRAT1T cell receptor associated transmembrane adaptor 1. (187 aa)
PIK3R2Phosphatidylinositol 3-kinase regulatory subunit beta. (727 aa)
PSMC226S protease regulatory subunit 7 isoform 1; Belongs to the AAA ATPase family. (433 aa)
PSMF1Proteasome inhibitor subunit 1. (288 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
TRBV15T cell receptor beta variable 15. (185 aa)
ENSMMUP00000081141IGv domain-containing protein. (210 aa)
TRBV11-1T cell receptor beta variable 11-1. (172 aa)
PSMA5Proteasome subunit alpha type. (241 aa)
PAK3Uncharacterized protein. (580 aa)
TRBV7-9T cell receptor beta variable 7-9. (155 aa)
ENSMMUP00000077599T cell receptor beta variable 23-1 (non-functional). (163 aa)
ENSMMUP00000076578Ig-like domain-containing protein. (275 aa)
HLA-DRB5Ig-like domain-containing protein. (287 aa)
ENSMMUP00000075705Ig-like domain-containing protein. (166 aa)
LOC114669810Ig-like domain-containing protein; Belongs to the MHC class II family. (266 aa)
PSMD11Proteasome 26S subunit, non-ATPase 11. (454 aa)
TRBV27T cell receptor beta variable 27. (148 aa)
LOC699631Proteasome subunit alpha type. (206 aa)
PSMB7Proteasome subunit beta. (277 aa)
ENAHENAH actin regulator. (805 aa)
TRBV29-1T cell receptor beta variable 29-1. (169 aa)
ENSMMUP00000071311UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (225 aa)
PSMA1Proteasome endopeptidase complex. (301 aa)
CSKTyrosine-protein kinase. (450 aa)
ENSMMUP00000070949IGv domain-containing protein. (185 aa)
TRAV29DV5T cell receptor alpha variable 29/delta variable 5 (gene/pseudogene). (152 aa)
ENSMMUP00000070235Ubiquitin-like domain-containing protein. (110 aa)
PAG1Phosphoprotein membrane anchor with glycosphingolipid microdomains 1. (432 aa)
ENSMMUP00000069379Ig-like domain-containing protein. (197 aa)
CD4T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...] (458 aa)
TRACT cell receptor alpha constant. (159 aa)
ENSMMUP00000069031Uncharacterized protein. (158 aa)
ENSMMUP00000068848IGv domain-containing protein. (229 aa)
ENSMMUP00000068350MHC_II_beta domain-containing protein. (103 aa)
SPNS1Sphingolipid transporter 1 (putative). (647 aa)
PSMB10Proteasome subunit beta. (312 aa)
ENSMMUP00000067421Ubiquitin-like domain-containing protein. (135 aa)
GRAP2GRB2 related adaptor protein 2. (348 aa)
CUL1Cullin 1; Belongs to the cullin family. (809 aa)
ENSMMUP00000065795Ig-like domain-containing protein. (231 aa)
TRBV7-4Ig-like domain-containing protein. (173 aa)
PSMD7MPN domain-containing protein. (323 aa)
TRAV19T cell receptor alpha variable 19. (187 aa)
TRBV7-2Ig-like domain-containing protein. (167 aa)
ENSMMUP00000064061Ig-like domain-containing protein. (262 aa)
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
Server load: low (16%) [HD]