STRINGSTRING
LOC696079 LOC696079 KLF2 KLF2 TNFAIP2 TNFAIP2 ERO1B ERO1B STX1A STX1A GH1 GH1 GNG13 GNG13 INHBC INHBC IGF1 IGF1 FAP FAP EXOC3 EXOC3 LHB LHB SEC11C SEC11C CTSG CTSG GNB3 GNB3 EXOC8 EXOC8 LEP LEP ENPEP ENPEP CPA3 CPA3 AGT AGT DPP6 DPP6 MME MME INHA INHA MYO5A MYO5A GRP GRP GPR119 GPR119 DPP4 DPP4 REN REN EXOC7 EXOC7 KIF5C KIF5C CES1 CES1 SPCS2 SPCS2 KIF5B KIF5B SLC30A4 SLC30A4 CRHR2 CRHR2 EXOC6B EXOC6B CDX4 CDX4 PCSK2 PCSK2 FFAR4 FFAR4 ANPEP ANPEP CTSZ CTSZ CGB8 CGB8 SPCS1 SPCS1 MYRIP MYRIP EXOC3L2 EXOC3L2 GATA4 GATA4 EXOC3L1 EXOC3L1 TCF7L2 TCF7L2 CPA6 CPA6 EXOC1 EXOC1 PHEX PHEX LOC114673168 LOC114673168 PDIA2 PDIA2 MMEL1 MMEL1 PCSK1 PCSK1 DPP10 DPP10 KIF5A KIF5A EXOC6 EXOC6 ATP6AP2 ATP6AP2 BCHE BCHE CSH2 CSH2 INS INS SLC30A6 SLC30A6 LOC718474 LOC718474 CSH4 CSH4 CPE CPE PLA2G7 PLA2G7 AOPEP AOPEP ENSMMUP00000080005 ENSMMUP00000080005 FFAR1 FFAR1 CDX2 CDX2 ENSMMUP00000078852 ENSMMUP00000078852 INHBB INHBB CLTRN CLTRN EXOC3L4 EXOC3L4 LOC114674119 LOC114674119 LOC100429320 LOC100429320 PAX6 PAX6 GNAT3 GNAT3 LOC707684 LOC707684 INHBA INHBA EXOC2 EXOC2 ACE2 ACE2 KLF4 KLF4 CDX1 CDX1 DPP9 DPP9 DPP8 DPP8 GIP GIP POMC POMC SPCS3 SPCS3 SLC30A7 SLC30A7 SLC30A8 SLC30A8 RAB27A RAB27A ALX3 ALX3 CGA CGA ENSMMUP00000072478 ENSMMUP00000072478 GCG GCG TSHB TSHB ENSMMUP00000070624 ENSMMUP00000070624 ENSMMUP00000070364 ENSMMUP00000070364 SLC30A5 SLC30A5 ENSMMUP00000069343 ENSMMUP00000069343 EXOC4 EXOC4 ENSMMUP00000067254 ENSMMUP00000067254 CPB1 CPB1 CMA1 CMA1 CPO CPO ISL1 ISL1 ISL2 ISL2 ACHE ACHE CTNNB1 CTNNB1 GHRL GHRL MBOAT4 MBOAT4 ENSMMUP00000061705 ENSMMUP00000061705 P4HB P4HB UCN UCN EXOC5 EXOC5 FSHB FSHB ACE ACE SEC11A SEC11A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC696079Signal peptidase complex catalytic subunit SEC11. (156 aa)
KLF2Kruppel like factor 2. (355 aa)
TNFAIP2TNF alpha induced protein 2. (790 aa)
ERO1BUncharacterized protein. (467 aa)
STX1ASyntaxin-1A isoform 1; Belongs to the syntaxin family. (288 aa)
GH1Uncharacterized protein. (234 aa)
GNG13Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (67 aa)
INHBCTGF_BETA_2 domain-containing protein. (356 aa)
IGF1Insulin like growth factor 1. (208 aa)
FAPFibroblast activation protein alpha; Belongs to the peptidase S9B family. (760 aa)
EXOC3Exocyst complex component 3. (745 aa)
LHBLuteinizing hormone beta subunit. (141 aa)
SEC11CSignal peptidase complex catalytic subunit SEC11. (209 aa)
CTSGCathepsin G; Belongs to the peptidase S1 family. (255 aa)
GNB3Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3. (340 aa)
EXOC8Exocyst complex component 8. (725 aa)
LEPLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways (By similarity). In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo-pituitary-adrenal hormones. In the periphery, inc [...] (167 aa)
ENPEPAminopeptidase. (957 aa)
CPA3Carboxypeptidase A3. (417 aa)
AGTAngiotensinogen preproprotein; Belongs to the serpin family. (485 aa)
DPP6Dipeptidyl peptidase like 6; Belongs to the peptidase S9B family. (864 aa)
MMEMembrane metalloendopeptidase. (750 aa)
INHAInhibin alpha chain; Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition; Belongs to the TGF-beta family. (366 aa)
MYO5AMyosin VA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1877 aa)
GRPGastrin releasing peptide. (161 aa)
GPR119G-protein coupled receptor 119; Belongs to the G-protein coupled receptor 1 family. (335 aa)
DPP4Dipeptidyl peptidase 4; Belongs to the peptidase S9B family. (766 aa)
RENRenin; Renin is a highly specific endopeptidase, whose only known function is to generate angiotensin I from angiotensinogen in the plasma, initiating a cascade of reactions that produce an elevation of blood pressure and increased sodium retention by the kidney. (433 aa)
EXOC7Exocyst complex component 7; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. (720 aa)
KIF5CKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (957 aa)
CES1Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (611 aa)
SPCS2Uncharacterized protein. (226 aa)
KIF5BKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (963 aa)
SLC30A4Solute carrier family 30 member 4. (429 aa)
CRHR2Corticotropin releasing hormone receptor 2; Belongs to the G-protein coupled receptor 2 family. (431 aa)
EXOC6BExocyst complex component; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. (815 aa)
CDX4Caudal-type homeobox protein 4. (284 aa)
PCSK2Neuroendocrine convertase 2 isoform 1 preproprotein; Belongs to the peptidase S8 family. (638 aa)
FFAR4Free fatty acid receptor 4. (377 aa)
ANPEPAminopeptidase. (966 aa)
CTSZCathepsin Z; Belongs to the peptidase C1 family. (303 aa)
CGB8Cys_knot domain-containing protein. (181 aa)
SPCS1Uncharacterized protein. (169 aa)
MYRIPMyosin VIIA and Rab interacting protein. (859 aa)
EXOC3L2Exocyst complex component 3 like 2. (409 aa)
GATA4GATA binding protein 4. (443 aa)
EXOC3L1Exocyst complex component 3 like 1. (746 aa)
TCF7L2Transcription factor 7 like 2. (632 aa)
CPA6Carboxypeptidase A6. (437 aa)
EXOC1Sec3-PIP2_bind domain-containing protein. (919 aa)
PHEXPhosphate regulating endopeptidase homolog X-linked. (749 aa)
LOC114673168Uncharacterized protein. (225 aa)
PDIA2Uncharacterized protein. (591 aa)
MMEL1Membrane metalloendopeptidase like 1. (779 aa)
PCSK1Neuroendocrine convertase 1 isoform 1 preproprotein; Belongs to the peptidase S8 family. (749 aa)
DPP10Uncharacterized protein; Belongs to the peptidase S9B family. (814 aa)
KIF5AKinesin heavy chain isoform 5A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1032 aa)
EXOC6Exocyst complex component; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. (822 aa)
ATP6AP2Renin/prorenin receptor. (350 aa)
BCHECholinesterase; Esterase with broad substrate specificity. Contributes to the inactivation of the neurotransmitter acetylcholine. Can degrade neurotoxic organophosphate esters (By similarity). (602 aa)
CSH2Uncharacterized protein. (248 aa)
INSInsulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (110 aa)
SLC30A6Solute carrier family 30 member 6. (461 aa)
LOC718474Growth hormone variant; Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues. (217 aa)
CSH4Somatotropin; Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues; Belongs to the somatotropin/prolactin family. (229 aa)
CPECarboxypeptidase E preproprotein. (476 aa)
PLA2G7Platelet-activating factor acetylhydrolase. (439 aa)
AOPEPAminopeptidase O (putative). (923 aa)
ENSMMUP00000080005Uncharacterized protein. (124 aa)
FFAR1Uncharacterized protein. (300 aa)
CDX2Caudal-type homeobox protein 2. (313 aa)
ENSMMUP00000078852Uncharacterized protein. (133 aa)
INHBBInhibin subunit beta B. (407 aa)
CLTRNTransmembrane protein 27. (222 aa)
EXOC3L4Exocyst complex component 3 like 4. (722 aa)
LOC114674119Choriogonadotropin subunit beta. (165 aa)
LOC100429320Cys_knot domain-containing protein. (165 aa)
PAX6Uncharacterized protein. (598 aa)
GNAT3G protein subunit alpha transducin 3. (354 aa)
LOC707684Uncharacterized protein. (157 aa)
INHBAInhibin subunit beta A. (426 aa)
EXOC2Exocyst complex component 2; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Belongs to the SEC5 family. (924 aa)
ACE2Angiotensin-converting enzyme. (805 aa)
KLF4Kruppel like factor 4. (544 aa)
CDX1Caudal type homeobox 1. (265 aa)
DPP9Dipeptidyl peptidase 9; Belongs to the peptidase S9B family. (913 aa)
DPP8Dipeptidyl peptidase 8; Belongs to the peptidase S9B family. (891 aa)
GIPGastric inhibitory polypeptide. (153 aa)
POMCUncharacterized protein. (392 aa)
SPCS3Signal peptidase complex subunit 3. (180 aa)
SLC30A7Solute carrier family 30 member 7. (376 aa)
SLC30A8Solute carrier family 30 member 8. (369 aa)
RAB27AUncharacterized protein. (321 aa)
ALX3ALX homeobox 3. (343 aa)
CGAGlycoprotein hormones alpha chain; Shared alpha chain of the active heterodimeric glycoprotein hormones thyrotropin/thyroid stimulating hormone/TSH, lutropin/luteinizing hormone/LH, follitropin/follicle stimulating hormone/FSH and choriogonadotropin/CG. These hormones bind specific receptors on target cells that in turn activate downstream signaling pathways. (161 aa)
ENSMMUP00000072478Uncharacterized protein. (103 aa)
GCGGlucagon. (263 aa)
TSHBThyroid stimulating hormone subunit beta. (158 aa)
ENSMMUP00000070624Uncharacterized protein. (195 aa)
ENSMMUP00000070364Uncharacterized protein. (101 aa)
SLC30A5Solute carrier family 30 member 5. (766 aa)
ENSMMUP00000069343Uncharacterized protein. (168 aa)
EXOC4Exocyst complex component 4 isoform a. (974 aa)
ENSMMUP00000067254Uncharacterized protein. (164 aa)
CPB1Carboxypeptidase B1. (417 aa)
CMA1Chymase 1; Belongs to the peptidase S1 family. (249 aa)
CPOCarboxypeptidase O. (374 aa)
ISL1ISL LIM homeobox 1. (413 aa)
ISL2ISL LIM homeobox 2. (359 aa)
ACHEUncharacterized protein; Belongs to the type-B carboxylesterase/lipase family. (848 aa)
CTNNB1Catenin beta-1. (781 aa)
GHRLGhrelin and obestatin prepropeptide. (222 aa)
MBOAT4Membrane bound O-acyltransferase domain containing 4; Belongs to the membrane-bound acyltransferase family. (445 aa)
ENSMMUP00000061705Uncharacterized protein. (105 aa)
P4HBProtein disulfide-isomerase. (510 aa)
UCNUrocortin. (124 aa)
EXOC5Exocyst complex component 5. (709 aa)
FSHBFollicle stimulating hormone subunit beta. (129 aa)
ACEAngiotensin-converting enzyme. (1307 aa)
SEC11ASignal peptidase complex catalytic subunit SEC11. (185 aa)
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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