STRINGSTRING
SCN10A SCN10A CLTA CLTA NCAM1 NCAM1 HSPA8 HSPA8 TUBA1C TUBA1C MAPK3 MAPK3 ENSMMUP00000053367 ENSMMUP00000053367 ACTB ACTB ITGA2 ITGA2 SCN1A SCN1A RPS6KA3 RPS6KA3 CNTN2 CNTN2 DCX DCX EPHB2 EPHB2 ACTRT1 ACTRT1 RPS6KA6 RPS6KA6 SPTAN1 SPTAN1 AP2A2 AP2A2 RPS6KA2 RPS6KA2 AP2S1 AP2S1 EGFR EGFR AP2M1 AP2M1 SPTBN1 SPTBN1 ACTG1 ACTG1 SPTB SPTB NUMB NUMB RPS6KA5 RPS6KA5 DPYSL2 DPYSL2 DLG3 DLG3 DLG1 DLG1 CSNK2A1 CSNK2A1 TUBA1A TUBA1A TUBA8 TUBA8 FNDC3A FNDC3A NRP1 NRP1 ANK2 ANK2 ANKDD1B ANKDD1B RANBP9 RANBP9 F6QAX2_MACMU F6QAX2_MACMU VSIG10L VSIG10L FGFR1 FGFR1 RPS6KA1 RPS6KA1 NRCAM NRCAM TUBA3D TUBA3D SPTBN4 SPTBN4 F7H9V3_MACMU F7H9V3_MACMU SPTBN2 SPTBN2 SRC SRC NRP2 NRP2 SCN11A SCN11A ANKRD60 ANKRD60 CNTNAP5 CNTNAP5 TUBA4A TUBA4A ITGAV ITGAV EZR EZR ACTL7A ACTL7A ACTL7B ACTL7B SCN3A SCN3A PAK1 PAK1 SCN7A SCN7A ITGB1 ITGB1 VAV2 VAV2 MAP2K1 MAP2K1 ITGA10 ITGA10 KCNQ2 KCNQ2 CSNK2A2 CSNK2A2 SCN5A SCN5A CNTNAP2 CNTNAP2 LAMC1 LAMC1 DNM2 DNM2 DNM1 DNM1 ITGA2B ITGA2B GAP43 GAP43 MAPK1 MAPK1 ACTRT2 ACTRT2 TUBB1 TUBB1 AP2A1 AP2A1 LAMA1 LAMA1 CLHC1 CLHC1 TUBB TUBB ACTL8 ACTL8 CLTC CLTC HMCN1 HMCN1 LOC705671 LOC705671 SPTA1 SPTA1 ALCAM ALCAM KCNQ3 KCNQ3 CNTN6 CNTN6 CNTNAP1 CNTNAP1 RPS6KA4 RPS6KA4 TUBB6 TUBB6 SHTN1 SHTN1 LOC709412 LOC709412 LOC707215 LOC707215 LAMB1 LAMB1 AP2B1 AP2B1 CSNK2B CSNK2B FNDC3B FNDC3B SPTBN5 SPTBN5 ITGA5 ITGA5 ANK3 ANK3 ITGB3 ITGB3 SCN2A SCN2A RDX RDX ITGA1 ITGA1 ACTL9 ACTL9 SCN4A SCN4A SCN8A SCN8A ENSMMUP00000081223 ENSMMUP00000081223 ENSMMUP00000080921 ENSMMUP00000080921 SCN3B SCN3B LOC100429145 LOC100429145 LOC704609 LOC704609 LOC114672614 LOC114672614 LYPLA2 LYPLA2 LOC711939 LOC711939 ITGA9 ITGA9 TUBB4A TUBB4A KIF4B KIF4B SH3GL2 SH3GL2 TUBB2B TUBB2B L1CAM L1CAM ENSMMUP00000072696 ENSMMUP00000072696 SCN4B SCN4B CNTN1 CNTN1 MCMDC2 MCMDC2 NCAM2 NCAM2 MSN MSN MAP2K2 MAP2K2 TUBAL3 TUBAL3 DLG4 DLG4 ENSMMUP00000068149 ENSMMUP00000068149 ENSMMUP00000066739 ENSMMUP00000066739 SCN2B SCN2B VSIG10L2 VSIG10L2 NFASC NFASC ANK1 ANK1 SCN1B SCN1B CHL1 CHL1 CNTNAP4 CNTNAP4 HMCN2 HMCN2 KIF4A KIF4A SDCBP SDCBP DNM3 DNM3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SCN10ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1956 aa)
CLTAClathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (248 aa)
NCAM1Neural cell adhesion molecule 1. (1119 aa)
HSPA8Heat shock cognate 71 kDa protein isoform 1; Belongs to the heat shock protein 70 family. (646 aa)
TUBA1CTubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (449 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
ENSMMUP00000053367Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. (333 aa)
ACTBUncharacterized protein. (421 aa)
ITGA2Integrin subunit alpha 2; Belongs to the integrin alpha chain family. (1180 aa)
SCN1ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2008 aa)
RPS6KA3Ribosomal protein S6 kinase. (755 aa)
CNTN2Uncharacterized protein. (1040 aa)
DCXDoublecortin. (387 aa)
EPHB2EPH receptor B2. (1082 aa)
ACTRT1Actin-related protein T1; Belongs to the actin family. (375 aa)
RPS6KA6Ribosomal protein S6 kinase. (860 aa)
SPTAN1Spectrin alpha chain, brain isoform 2. (2472 aa)
AP2A2AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (939 aa)
RPS6KA2Ribosomal protein S6 kinase. (758 aa)
AP2S1Clat_adaptor_s domain-containing protein. (240 aa)
EGFREpidermal growth factor receptor; Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, AREG, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. Activates at least [...] (1210 aa)
AP2M1AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...] (459 aa)
SPTBN1Spectrin beta chain; Belongs to the spectrin family. (2364 aa)
ACTG1Actin, cytoplasmic 2. (375 aa)
SPTBSpectrin beta chain; Belongs to the spectrin family. (2326 aa)
NUMBNUMB endocytic adaptor protein. (711 aa)
RPS6KA5Ribosomal protein S6 kinase. (802 aa)
DPYSL2Dihydropyrimidinase like 2. (681 aa)
DLG3Uncharacterized protein; Belongs to the MAGUK family. (867 aa)
DLG1Disks large homolog 1 isoform 2; Belongs to the MAGUK family. (926 aa)
CSNK2A1Casein kinase II subunit alpha isoform a; Belongs to the protein kinase superfamily. (391 aa)
TUBA1ATubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (456 aa)
TUBA8Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (454 aa)
FNDC3AFibronectin type-III domain-containing protein 3A isoform 1. (1198 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (923 aa)
ANK2Ankyrin 2. (4045 aa)
ANKDD1BAnkyrin repeat and death domain containing 1B. (528 aa)
RANBP9RAN binding protein 9. (732 aa)
F6QAX2_MACMUTubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (450 aa)
VSIG10LV-set and immunoglobulin domain containing 10 like. (999 aa)
FGFR1Fibroblast growth factor receptor. (853 aa)
RPS6KA1Ribosomal protein S6 kinase. (744 aa)
NRCAMNeuronal cell adhesion molecule. (1308 aa)
TUBA3DTubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (459 aa)
SPTBN4Spectrin beta chain, brain 3 isoform sigma5. (678 aa)
F7H9V3_MACMUUncharacterized protein. (584 aa)
SPTBN2Spectrin beta chain; Belongs to the spectrin family. (2390 aa)
SRCTyrosine-protein kinase. (644 aa)
NRP2Neuropilin; Belongs to the neuropilin family. (925 aa)
SCN11ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1790 aa)
ANKRD60Ankyrin repeat domain 60. (344 aa)
CNTNAP5Contactin associated protein like 5. (1305 aa)
TUBA4ATubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (457 aa)
ITGAVIntegrin_alpha2 domain-containing protein; Belongs to the integrin alpha chain family. (1051 aa)
EZREzrin. (598 aa)
ACTL7AActin like 7A; Belongs to the actin family. (435 aa)
ACTL7BActin-like-7-beta; Belongs to the actin family. (415 aa)
SCN3ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2000 aa)
PAK1Non-specific serine/threonine protein kinase. (575 aa)
SCN7ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1977 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (801 aa)
VAV2Guanine nucleotide exchange factor VAV2 isoform 1. (878 aa)
MAP2K1Dual specificity mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
ITGA10Integrin subunit alpha 10; Belongs to the integrin alpha chain family. (1167 aa)
KCNQ2Potassium voltage-gated channel subfamily Q member 2. (1110 aa)
CSNK2A2Casein kinase II subunit alpha; Belongs to the protein kinase superfamily. (350 aa)
SCN5ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2017 aa)
CNTNAP2Contactin associated protein like 2. (1331 aa)
LAMC1Laminin subunit gamma-1. (1608 aa)
DNM2Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (880 aa)
DNM1Dynamin-1 isoform 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (864 aa)
ITGA2BIntegrin subunit alpha 2b; Belongs to the integrin alpha chain family. (1090 aa)
GAP43Growth associated protein 43. (238 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa)
ACTRT2Actin related protein T2; Belongs to the actin family. (377 aa)
TUBB1Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (451 aa)
AP2A1AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (1002 aa)
LAMA1Uncharacterized protein. (528 aa)
CLHC1Clathrin heavy chain linker domain-containing protein 1. (586 aa)
TUBBTubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. (507 aa)
ACTL8Actin like 8; Belongs to the actin family. (366 aa)
CLTCClathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1675 aa)
HMCN1Hemicentin 1. (5635 aa)
LOC705671Uncharacterized protein. (398 aa)
SPTA1Spectrin alpha, erythrocytic 1. (2420 aa)
ALCAMCD166 antigen isoform 1. (583 aa)
KCNQ3Potassium voltage-gated channel subfamily KQT member 3 isoform 1; Belongs to the potassium channel family. (872 aa)
CNTN6Neural recognition molecule NB-3. (1029 aa)
CNTNAP1Uncharacterized protein. (1382 aa)
RPS6KA4Ribosomal protein S6 kinase. (772 aa)
TUBB6Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (446 aa)
SHTN1Shootin 1. (676 aa)
LOC709412Uncharacterized protein; Belongs to the heat shock protein 70 family. (590 aa)
LOC707215Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (450 aa)
LAMB1Laminin subunit beta 1. (1786 aa)
AP2B1AP complex subunit beta. (949 aa)
CSNK2BChimera Csnk2b-Ly6g5b splicing isoform 992. (298 aa)
FNDC3BFibronectin type III domain containing 3B. (1206 aa)
SPTBN5Spectrin beta, non-erythrocytic 5. (3697 aa)
ITGA5Integrin subunit alpha 5; Belongs to the integrin alpha chain family. (1049 aa)
ANK3Ankyrin 3. (4375 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (741 aa)
SCN2ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2005 aa)
RDXRadixin. (604 aa)
ITGA1Integrin subunit alpha 1; Belongs to the integrin alpha chain family. (1174 aa)
ACTL9Uncharacterized protein; Belongs to the actin family. (416 aa)
SCN4ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1836 aa)
SCN8ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1980 aa)
ENSMMUP00000081223ANK_REP_REGION domain-containing protein. (548 aa)
ENSMMUP00000080921Uncharacterized protein. (232 aa)
SCN3BIg-like domain-containing protein. (240 aa)
LOC100429145Uncharacterized protein. (1309 aa)
LOC704609Uncharacterized protein; Belongs to the actin family. (912 aa)
LOC114672614Uncharacterized protein. (137 aa)
LYPLA2Acyl-protein thioesterase 2. (231 aa)
LOC711939Uncharacterized protein. (1341 aa)
ITGA9Integrin_alpha2 domain-containing protein; Belongs to the integrin alpha chain family. (1040 aa)
TUBB4ATubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (444 aa)
KIF4BKinesin family member 4B; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1177 aa)
SH3GL2SH3 domain containing GRB2 like 2, endophilin A1. (383 aa)
TUBB2BTubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (445 aa)
L1CAMUncharacterized protein. (1420 aa)
ENSMMUP00000072696Uncharacterized protein. (103 aa)
SCN4BSodium voltage-gated channel beta subunit 4. (316 aa)
CNTN1Contactin-1 isoform 1. (1018 aa)
MCMDC2Minichromosome maintenance domain containing 2. (681 aa)
NCAM2Neural cell adhesion molecule 2. (855 aa)
MSNFERM domain-containing protein. (592 aa)
MAP2K2Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (411 aa)
TUBAL3Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (446 aa)
DLG4Uncharacterized protein; Belongs to the MAGUK family. (972 aa)
ENSMMUP00000068149Uncharacterized protein. (237 aa)
ENSMMUP00000066739Uncharacterized protein. (195 aa)
SCN2BSodium voltage-gated channel beta subunit 2. (215 aa)
VSIG10L2V-set and immunoglobulin domain containing 10 like 2. (767 aa)
NFASCNeurofascin. (1464 aa)
ANK1Ankyrin 1. (2026 aa)
SCN1BSodium voltage-gated channel beta subunit 1. (402 aa)
CHL1Cell adhesion molecule L1 like. (1225 aa)
CNTNAP4Contactin associated protein like 4. (1308 aa)
HMCN2Hemicentin 2. (5002 aa)
KIF4AChromosome-associated kinesin KIF4A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1234 aa)
SDCBPSyndecan binding protein. (324 aa)
DNM3Dynamin 3; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (869 aa)
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
Server load: low (20%) [HD]