12 items (Macaca mulatta) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	VAV1	Vav guanine nucleotide exchange factor 1. (928 aa)
	PAK2	Non-specific serine/threonine protein kinase. (524 aa)
	PAK1	Non-specific serine/threonine protein kinase. (575 aa)
	CDC42	Cell division control protein 42 homolog isoform 1. (191 aa)
	CD276	CD276 molecule. (613 aa)
	FYN	Tyrosine-protein kinase. (589 aa)
	PAK3	Uncharacterized protein. (580 aa)
	CD80	CD80 molecule. (288 aa)
	LCK	Tyrosine-protein kinase. (567 aa)
	GRB2	Growth factor receptor-bound protein 2 isoform 1. (217 aa)
	CD86	CD86 molecule. (417 aa)
	CD28	T-cell-specific surface glycoprotein CD28. (220 aa)

Your Current Organism:

Macaca mulatta

NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CD276	CD28	ENSMMUP00000080536	ENSMMUP00000065245	CD276 molecule.	T-cell-specific surface glycoprotein CD28.	0.738
CD276	CD80	ENSMMUP00000080536	ENSMMUP00000074900	CD276 molecule.	CD80 molecule.	0.664
CD276	CD86	ENSMMUP00000080536	ENSMMUP00000051608	CD276 molecule.	CD86 molecule.	0.653
CD28	CD276	ENSMMUP00000065245	ENSMMUP00000080536	T-cell-specific surface glycoprotein CD28.	CD276 molecule.	0.738
CD28	CD80	ENSMMUP00000065245	ENSMMUP00000074900	T-cell-specific surface glycoprotein CD28.	CD80 molecule.	0.999
CD28	CD86	ENSMMUP00000065245	ENSMMUP00000051608	T-cell-specific surface glycoprotein CD28.	CD86 molecule.	0.999
CD28	CDC42	ENSMMUP00000065245	ENSMMUP00000040537	T-cell-specific surface glycoprotein CD28.	Cell division control protein 42 homolog isoform 1.	0.494
CD28	FYN	ENSMMUP00000065245	ENSMMUP00000080137	T-cell-specific surface glycoprotein CD28.	Tyrosine-protein kinase.	0.617
CD28	GRB2	ENSMMUP00000065245	ENSMMUP00000045339	T-cell-specific surface glycoprotein CD28.	Growth factor receptor-bound protein 2 isoform 1.	0.987
CD28	LCK	ENSMMUP00000065245	ENSMMUP00000044699	T-cell-specific surface glycoprotein CD28.	Tyrosine-protein kinase.	0.805
CD28	PAK1	ENSMMUP00000065245	ENSMMUP00000024698	T-cell-specific surface glycoprotein CD28.	Non-specific serine/threonine protein kinase.	0.401
CD28	PAK2	ENSMMUP00000065245	ENSMMUP00000015786	T-cell-specific surface glycoprotein CD28.	Non-specific serine/threonine protein kinase.	0.505
CD28	PAK3	ENSMMUP00000065245	ENSMMUP00000078285	T-cell-specific surface glycoprotein CD28.	Uncharacterized protein.	0.404
CD28	VAV1	ENSMMUP00000065245	ENSMMUP00000058900	T-cell-specific surface glycoprotein CD28.	Vav guanine nucleotide exchange factor 1.	0.560
CD80	CD276	ENSMMUP00000074900	ENSMMUP00000080536	CD80 molecule.	CD276 molecule.	0.664
CD80	CD28	ENSMMUP00000074900	ENSMMUP00000065245	CD80 molecule.	T-cell-specific surface glycoprotein CD28.	0.999
CD80	CD86	ENSMMUP00000074900	ENSMMUP00000051608	CD80 molecule.	CD86 molecule.	0.998
CD80	CDC42	ENSMMUP00000074900	ENSMMUP00000040537	CD80 molecule.	Cell division control protein 42 homolog isoform 1.	0.597
CD80	FYN	ENSMMUP00000074900	ENSMMUP00000080137	CD80 molecule.	Tyrosine-protein kinase.	0.414
CD80	GRB2	ENSMMUP00000074900	ENSMMUP00000045339	CD80 molecule.	Growth factor receptor-bound protein 2 isoform 1.	0.609