STRINGSTRING
GNA15 GNA15 GNAQ GNAQ CCT8 CCT8 PFDN4 PFDN4 TBCD TBCD CCT7 CCT7 AP3M2 AP3M2 TUBA1C TUBA1C AP3M1 AP3M1 ACTB ACTB ENSMMUP00000052038 ENSMMUP00000052038 GNG3 GNG3 GNG11 GNG11 GNGT1 GNGT1 TBCE TBCE CCT6B CCT6B XRN2 XRN2 SKIV2L SKIV2L FBXW7 FBXW7 SPHK1 SPHK1 CCT5 CCT5 FBXW10 FBXW10 ACTG1 ACTG1 STAT3 STAT3 FBXO44 FBXO44 CCT2 CCT2 CCT3 CCT3 CSNK2A1 CSNK2A1 TUBA1A TUBA1A TUBA8 TUBA8 HDAC3 HDAC3 ERMARD ERMARD RGS11 RGS11 RGS6 RGS6 F6QAX2_MACMU F6QAX2_MACMU CCNE2 CCNE2 KIF13A KIF13A GNG5 GNG5 PFDN5 PFDN5 FBXL3 FBXL3 TUBA3D TUBA3D CCNE1 CCNE1 ARFGEF2 ARFGEF2 TUBA4A TUBA4A GNB5 GNB5 GNA14 GNA14 USP11 USP11 CSNK2A2 CSNK2A2 KIFC3 KIFC3 CCT6A CCT6A VBP1 VBP1 RGS9 RGS9 ARFGEF1 ARFGEF1 FAM161A FAM161A NOP56 NOP56 FKBP10 FKBP10 TCP1 TCP1 ARL2 ARL2 TUBB1 TUBB1 FKBP9 FKBP9 FBXW5 FBXW5 RGS7 RGS7 LOC705671 LOC705671 FBXL5 FBXL5 TP53 TP53 WRAP53 WRAP53 TUBB6 TUBB6 LONP2 LONP2 PDCL PDCL LOC707215 LOC707215 CSNK2B CSNK2B GNB3 GNB3 GNB4 GNB4 FBXO4 FBXO4 PFDN6 PFDN6 GNA11 GNA11 FBXW2 FBXW2 TBCC TBCC GNG13 GNG13 GAPDHS GAPDHS TBCB TBCB PDC PDC FBXW4 FBXW4 ENSMMUP00000080065 ENSMMUP00000080065 ENSMMUP00000074832 ENSMMUP00000074832 TUBB2B TUBB2B FBXW9 FBXW9 TBCA TBCA FBXO6 FBXO6 GNB2 GNB2 PFDN1 PFDN1 TUBAL3 TUBAL3 CCT8L2 CCT8L2 GNG7 GNG7 GBA GBA LOC712612 LOC712612 PFDN2 PFDN2 GNB1 GNB1 ENSMMUP00000066739 ENSMMUP00000066739 GNG4 GNG4 CCT4 CCT4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GNA15Uncharacterized protein. (414 aa)
GNAQGuanine nucleotide-binding protein G(Q) subunit alpha. (359 aa)
CCT8Uncharacterized protein. (553 aa)
PFDN4Prefoldin subunit 4; Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins; Belongs to the prefoldin subunit beta family. (134 aa)
TBCDTubulin folding cofactor D. (1257 aa)
CCT7T-complex protein 1 subunit eta; Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin. (651 aa)
AP3M2AP-3 complex subunit mu-2. (418 aa)
TUBA1CTubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (449 aa)
AP3M1AP-3 complex subunit mu-1; Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes; Belongs to the adaptor complexes medium subunit family. (418 aa)
ACTBUncharacterized protein. (421 aa)
ENSMMUP00000052038Ubiquitin-like domain-containing protein. (63 aa)
GNG3Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (152 aa)
GNG11Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa)
GNGT1Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
TBCECAP-Gly domain-containing protein. (578 aa)
CCT6BChaperonin containing TCP1 subunit 6B. (531 aa)
XRN25'-3' exoribonuclease; Possesses 5'->3' exoribonuclease activity. May promote termination of transcription by RNA polymerase II. (950 aa)
SKIV2LSki2 like RNA helicase. (1246 aa)
FBXW7F-box/WD repeat-containing protein 7 isoform 1. (707 aa)
SPHK1Sphingosine kinase 1. (470 aa)
CCT5T-complex protein 1 subunit epsilon. (541 aa)
FBXW10WD_REPEATS_REGION domain-containing protein. (1050 aa)
ACTG1Actin, cytoplasmic 2. (375 aa)
STAT3Signal transducer and activator of transcription. (871 aa)
FBXO44F-box only protein 44 isoform 1. (255 aa)
CCT2Chaperonin containing TCP1 subunit 2. (589 aa)
CCT3T-complex protein 1 subunit gamma. (545 aa)
CSNK2A1Casein kinase II subunit alpha isoform a; Belongs to the protein kinase superfamily. (391 aa)
TUBA1ATubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (456 aa)
TUBA8Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (454 aa)
HDAC3Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (428 aa)
ERMARDER membrane associated RNA degradation. (764 aa)
RGS11Regulator of G protein signaling 11. (540 aa)
RGS6Uncharacterized protein. (491 aa)
F6QAX2_MACMUTubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (450 aa)
CCNE2Cyclin E2; Belongs to the cyclin family. (426 aa)
KIF13AKinesin family member 13A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1822 aa)
GNG5Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
PFDN5Prefoldin subunit 5 isoform alpha. (154 aa)
FBXL3F-box and leucine-rich repeat protein 3A. (428 aa)
TUBA3DTubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (459 aa)
CCNE1Cyclin E1; Belongs to the cyclin family. (410 aa)
ARFGEF2ADP ribosylation factor guanine nucleotide exchange factor 2. (1785 aa)
TUBA4ATubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (457 aa)
GNB5G protein subunit beta 5. (395 aa)
GNA14G protein subunit alpha 14. (355 aa)
USP11Ubiquitin specific peptidase 11; Belongs to the peptidase C19 family. (866 aa)
CSNK2A2Casein kinase II subunit alpha; Belongs to the protein kinase superfamily. (350 aa)
KIFC3Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (871 aa)
CCT6AT-complex protein 1 subunit zeta isoform a. (531 aa)
VBP1Prefoldin subunit 3; Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins; Belongs to the prefoldin subunit alpha family. (197 aa)
RGS9Regulator of G protein signaling 9. (658 aa)
ARFGEF1ADP ribosylation factor guanine nucleotide exchange factor 1. (1849 aa)
FAM161AFAM161 centrosomal protein A. (716 aa)
NOP56NOP56 ribonucleoprotein. (594 aa)
FKBP10Peptidylprolyl isomerase. (582 aa)
TCP1T-complex protein 1 subunit alpha isoform a. (556 aa)
ARL2ADP-ribosylation factor-like protein 2 isoform 1; Belongs to the small GTPase superfamily. Arf family. (184 aa)
TUBB1Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (451 aa)
FKBP9Peptidylprolyl isomerase. (676 aa)
FBXW5F-box and WD repeat domain containing 5. (566 aa)
RGS7Regulator of G protein signaling 7. (487 aa)
LOC705671Uncharacterized protein. (398 aa)
FBXL5F-box and leucine rich repeat protein 5. (765 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...] (433 aa)
WRAP53Telomerase Cajal body protein 1. (548 aa)
TUBB6Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (446 aa)
LONP2Lon protease homolog 2, peroxisomal; ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import. May indirectly regulate peroxisomal fatty acid beta- oxidation through degradation of the self-processed forms of TYSND1. (853 aa)
PDCLPhosducin-like protein. (301 aa)
LOC707215Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (450 aa)
CSNK2BChimera Csnk2b-Ly6g5b splicing isoform 992. (298 aa)
GNB3Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3. (340 aa)
GNB4Guanine nucleotide-binding protein subunit beta-4. (340 aa)
FBXO4F-box protein 4. (490 aa)
PFDN6Prefoldin subunit 6. (129 aa)
GNA11Guanine nucleotide-binding protein subunit alpha-11. (359 aa)
FBXW2F-box and WD repeat domain containing 2. (477 aa)
TBCCTubulin-specific chaperone C. (346 aa)
GNG13Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (67 aa)
GAPDHSGlyceraldehyde-3-phosphate dehydrogenase. (409 aa)
TBCBTubulin-folding cofactor B. (244 aa)
PDCPhosducin. (246 aa)
FBXW4F-box and WD repeat domain containing 4. (591 aa)
ENSMMUP00000080065Uncharacterized protein. (73 aa)
ENSMMUP00000074832Prefoldin subunit 3; Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins; Belongs to the prefoldin subunit alpha family. (197 aa)
TUBB2BTubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (445 aa)
FBXW9F-box and WD repeat domain containing 9. (502 aa)
TBCATubulin folding cofactor A. (108 aa)
FBXO6F-box protein 6. (428 aa)
GNB2Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2. (340 aa)
PFDN1Prefoldin subunit 1. (142 aa)
TUBAL3Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (446 aa)
CCT8L2Chaperonin containing TCP1 subunit 8 like 2. (557 aa)
GNG7Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
GBAGlucosylceramidase. (533 aa)
LOC712612Tubulin-specific chaperone A; Belongs to the TBCA family. (108 aa)
PFDN2Prefoldin subunit 2. (154 aa)
GNB1Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1. (340 aa)
ENSMMUP00000066739Uncharacterized protein. (195 aa)
GNG4Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (71 aa)
CCT4T-complex protein 1 subunit delta. (737 aa)
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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