76 items (Macaca mulatta) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ARHGEF26	Rho guanine nucleotide exchange factor 26. (910 aa)
	ROCK2	Uncharacterized protein; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1474 aa)
	ABR	ABR activator of RhoGEF and GTPase. (1131 aa)
	FGD2	FYVE, RhoGEF and PH domain containing 2. (655 aa)
	FGD4	FYVE, RhoGEF and PH domain containing 4. (931 aa)
	NGEF	Neuronal guanine nucleotide exchange factor. (712 aa)
	ADRA1A	Adrenoceptor alpha 1A. (445 aa)
	TIAM1	Uncharacterized protein. (1591 aa)
	VAV1	Vav guanine nucleotide exchange factor 1. (928 aa)
	ARHGEF3	Rho guanine nucleotide exchange factor 3 isoform 1. (558 aa)
	ARHGEF9	Cdc42 guanine nucleotide exchange factor 9. (545 aa)
	TGM6	Transglutaminase 6. (706 aa)
	ARHGEF10L	Rho guanine nucleotide exchange factor 10 like. (1277 aa)
	ADRA1D	Adrenoceptor alpha 1D. (570 aa)
	GNG4	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (71 aa)
	GNB1	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1. (340 aa)
	SOS1	SOS Ras/Rac guanine nucleotide exchange factor 1. (1345 aa)
	GNG7	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
	GNB2	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2. (340 aa)
	TGM3	TGc domain-containing protein. (712 aa)
	MCF2L	MCF.2 cell line derived transforming sequence like. (1178 aa)
	TIAM2	T cell lymphoma invasion and metastasis 2. (1701 aa)
	ARHGEF1	Rho guanine nucleotide exchange factor 1. (1021 aa)
	GNG5	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
	PLEKHG5	Pleckstrin homology and RhoGEF domain containing G5. (1155 aa)
	SESTD1	SEC14 domain and spectrin repeat-containing protein 1. (696 aa)
	ARHGEF37	Rho guanine nucleotide exchange factor 37. (675 aa)
	NET1	Neuroepithelial cell-transforming gene 1 protein isoform 1. (596 aa)
	GNB5	G protein subunit beta 5. (395 aa)
	VAV2	Guanine nucleotide exchange factor VAV2 isoform 1. (878 aa)
	KALRN	Uncharacterized protein. (2987 aa)
	GNA13	G protein subunit alpha 13. (409 aa)
	TRIO	Trio Rho guanine nucleotide exchange factor. (3093 aa)
	ARHGEF19	Rho guanine nucleotide exchange factor 19. (809 aa)
	ARHGEF6	Rac/Cdc42 guanine nucleotide exchange factor 6. (775 aa)
	ARHGEF7	Rho guanine nucleotide exchange factor 7. (862 aa)
	AKAP13	A-kinase anchoring protein 13. (2899 aa)
	ARHGEF38	Rho guanine nucleotide exchange factor 38. (777 aa)
	ARHGEF5	Rho guanine nucleotide exchange factor 5. (1597 aa)
	ARHGEF16	Rho guanine nucleotide exchange factor 16. (709 aa)
	ARHGEF15	Rho guanine nucleotide exchange factor 15. (841 aa)
	GNB3	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3. (340 aa)
	ARHGEF2	Rho/Rac guanine nucleotide exchange factor 2. (1245 aa)
	GNB4	Guanine nucleotide-binding protein subunit beta-4. (340 aa)
	ARHGEF17	Rho guanine nucleotide exchange factor 17. (2069 aa)
	MCF2L2	MCF.2 cell line derived transforming sequence-like 2. (1114 aa)
	GNG13	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (67 aa)
	PLEKHG2	Pleckstrin homology and RhoGEF domain containing G2. (1387 aa)
	GNG3	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (152 aa)
	GNG11	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa)
	GNA12	G protein subunit alpha 12. (463 aa)
	PLXNB1	Plexin B1. (2140 aa)
	GNGT1	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
	ROCK1	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1354 aa)
	ARHGEF11	Rho guanine nucleotide exchange factor 11. (1562 aa)
	SOS2	Uncharacterized protein. (1332 aa)
	ARHGEF33	Rho guanine nucleotide exchange factor 33. (872 aa)
	RASGRF2	Ras protein specific guanine nucleotide releasing factor 2. (1237 aa)
	RHOA	Ras homolog family member A. (209 aa)
	ARHGEF40	Rho guanine nucleotide exchange factor 40. (1761 aa)
	VAV3	Vav guanine nucleotide exchange factor 3. (1128 aa)
	TBXA2R	Thromboxane A2 receptor. (343 aa)
	PREX1	Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1. (1661 aa)
	ARHGEF18	Uncharacterized protein. (1591 aa)
	ADRA1B	Adrenoceptor alpha 1B. (518 aa)
	ARHGEF4	Uncharacterized protein. (1924 aa)
	ARHGEF10	Rho guanine nucleotide exchange factor 10. (1345 aa)
	ARHGEF12	Rho guanine nucleotide exchange factor 12. (1544 aa)
	ECT2L	Epithelial cell transforming 2 like. (916 aa)
	MCF2	MCF.2 cell line derived transforming sequence. (1002 aa)
	FGD1	FYVE, RhoGEF and PH domain-containing protein 1. (961 aa)
	ITSN1	Intersectin 1. (1720 aa)
	BTK	Tyrosine-protein kinase. (659 aa)
	ARHGEF39	Vav-like protein C9orf100. (335 aa)
	FGD3	FYVE, RhoGEF and PH domain containing 3. (737 aa)
	ECT2	Epithelial cell transforming 2. (958 aa)

Your Current Organism:

Macaca mulatta

NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABR	ARHGEF18	ENSMMUP00000035457	ENSMMUP00000080402	ABR activator of RhoGEF and GTPase.	Uncharacterized protein.	0.928
ABR	RHOA	ENSMMUP00000035457	ENSMMUP00000045801	ABR activator of RhoGEF and GTPase.	Ras homolog family member A.	0.691
ABR	TIAM1	ENSMMUP00000035457	ENSMMUP00000058425	ABR activator of RhoGEF and GTPase.	Uncharacterized protein.	0.450
ADRA1A	ADRA1B	ENSMMUP00000054425	ENSMMUP00000080927	Adrenoceptor alpha 1A.	Adrenoceptor alpha 1B.	0.943
ADRA1A	ADRA1D	ENSMMUP00000054425	ENSMMUP00000064197	Adrenoceptor alpha 1A.	Adrenoceptor alpha 1D.	0.936
ADRA1A	ARHGEF1	ENSMMUP00000054425	ENSMMUP00000029363	Adrenoceptor alpha 1A.	Rho guanine nucleotide exchange factor 1.	0.430
ADRA1A	ARHGEF11	ENSMMUP00000054425	ENSMMUP00000046962	Adrenoceptor alpha 1A.	Rho guanine nucleotide exchange factor 11.	0.430
ADRA1A	ARHGEF12	ENSMMUP00000054425	ENSMMUP00000054674	Adrenoceptor alpha 1A.	Rho guanine nucleotide exchange factor 12.	0.524
ADRA1A	GNA12	ENSMMUP00000054425	ENSMMUP00000051095	Adrenoceptor alpha 1A.	G protein subunit alpha 12.	0.961
ADRA1A	GNA13	ENSMMUP00000054425	ENSMMUP00000021495	Adrenoceptor alpha 1A.	G protein subunit alpha 13.	0.961
ADRA1A	GNB1	ENSMMUP00000054425	ENSMMUP00000066781	Adrenoceptor alpha 1A.	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1.	0.482
ADRA1A	GNB2	ENSMMUP00000054425	ENSMMUP00000071351	Adrenoceptor alpha 1A.	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2.	0.482
ADRA1A	GNB3	ENSMMUP00000054425	ENSMMUP00000006868	Adrenoceptor alpha 1A.	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3.	0.553
ADRA1A	GNB4	ENSMMUP00000054425	ENSMMUP00000005459	Adrenoceptor alpha 1A.	Guanine nucleotide-binding protein subunit beta-4.	0.482
ADRA1A	GNB5	ENSMMUP00000054425	ENSMMUP00000022869	Adrenoceptor alpha 1A.	G protein subunit beta 5.	0.605
ADRA1A	GNG11	ENSMMUP00000054425	ENSMMUP00000051134	Adrenoceptor alpha 1A.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.451
ADRA1A	GNG13	ENSMMUP00000054425	ENSMMUP00000001138	Adrenoceptor alpha 1A.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.545
ADRA1A	GNG3	ENSMMUP00000054425	ENSMMUP00000051192	Adrenoceptor alpha 1A.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.491
ADRA1A	GNG4	ENSMMUP00000054425	ENSMMUP00000064430	Adrenoceptor alpha 1A.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.631
ADRA1A	GNG5	ENSMMUP00000054425	ENSMMUP00000029198	Adrenoceptor alpha 1A.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.546