STRINGSTRING
HDAC1 HDAC1 SAP30L SAP30L ZNRD1 ZNRD1 DNMT1 DNMT1 POLR1A POLR1A LOC699443 LOC699443 POLR1E POLR1E LOC106996511-5 LOC106996511-5 ENSMMUP00000068277 ENSMMUP00000068277 LOC693939 LOC693939 ENSMMUP00000067674 ENSMMUP00000067674 LOC698105 LOC698105 ENSMMUP00000066392 ENSMMUP00000066392 LOC696808-3 LOC696808-3 LOC696808-2 LOC696808-2 ERCC3 ERCC3 LOC106996511-4 LOC106996511-4 LOC697115 LOC697115 LOC106996511-3 LOC106996511-3 LOC696808 LOC696808 H3C8 H3C8 GTF2H5 GTF2H5 GTF2H1 GTF2H1 LOC106996511-2 LOC106996511-2 HIST1H3D HIST1H3D LOC704104 LOC704104 LOC106995531 LOC106995531 LOC696506 LOC696506 GTF2H3 GTF2H3 H2BE1 H2BE1 HDAC2 HDAC2 UBTF UBTF POLR2F POLR2F LOC114669830 LOC114669830 GTF2H2 GTF2H2 H2BC5 H2BC5 TAF1B TAF1B LOC710748 LOC710748 CCNH CCNH HIST1H2AC HIST1H2AC TBP TBP LOC106996511 LOC106996511 H2AFZ H2AFZ ERCC2 ERCC2 POLR2E POLR2E MNAT1 MNAT1 POLR2H POLR2H H2AFX H2AFX MBD2 MBD2 LOC699317 LOC699317 TTF1 TTF1 F7GDN6_MACMU F7GDN6_MACMU F6PS34_MACMU F6PS34_MACMU F7C6W4_MACMU F7C6W4_MACMU LOC714001 LOC714001 POLR1C POLR1C SIN3B SIN3B HIST1H2BA HIST1H2BA SAP130 SAP130 SUDS3 SUDS3 BAZ2A BAZ2A CDK7 CDK7 H2AFJ H2AFJ H2BC15 H2BC15 LOC695427 LOC695427 GTF2H4 GTF2H4 H2AFV H2AFV HIST1H2BK HIST1H2BK TAF1C TAF1C HIST1H2BO HIST1H2BO TAF1D TAF1D LOC697721 LOC697721 LOC100430668 LOC100430668 LOC699110 LOC699110 LOC695323 LOC695323 CD3EAP CD3EAP SMARCA5 SMARCA5 LOC695427-2 LOC695427-2 H2BU1 H2BU1 H2AC20 H2AC20 SAP30 SAP30 LOC708899 LOC708899 LOC693887 LOC693887 SAP30BP SAP30BP LOC703889 LOC703889 LOC704341 LOC704341 LOC106996511-6 LOC106996511-6 LOC698354 LOC698354 LOC718280 LOC718280 HIST1H2BJ HIST1H2BJ BAZ2B BAZ2B ARID4B ARID4B TAF1A TAF1A SMARCA1 SMARCA1 SIN3A SIN3A TTL TTL H2AFB3 H2AFB3 TWISTNB TWISTNB SAP18 SAP18
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
HDAC1Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (482 aa)
SAP30LHistone deacetylase complex subunit SAP30L isoform 1. (184 aa)
ZNRD1DNA-directed RNA polymerase I subunit RPA12; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase I which synthesizes ribosomal RNA precursors. (132 aa)
DNMT1DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (1717 aa)
POLR1ADNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1721 aa)
LOC699443Histone H3; Belongs to the histone H3 family. (136 aa)
POLR1ERNA polymerase I subunit E. (484 aa)
LOC106996511-5Histone H4. (103 aa)
ENSMMUP00000068277Histone H3; Belongs to the histone H3 family. (136 aa)
LOC693939Histone H3; Belongs to the histone H3 family. (136 aa)
ENSMMUP00000067674Uncharacterized protein. (87 aa)
LOC698105Histone H3.1. (136 aa)
ENSMMUP00000066392annotation not available (136 aa)
LOC696808-3Histone H2B type 1. (126 aa)
LOC696808-2Histone H2B type 1. (126 aa)
ERCC3TFIIH basal transcription factor complex helicase XPB subunit. (782 aa)
LOC106996511-4Histone H4. (103 aa)
LOC697115Histone H4. (103 aa)
LOC106996511-3Histone H4. (103 aa)
LOC696808Histone H2B type 1. (126 aa)
H3C8H3 clustered histone 8. (136 aa)
GTF2H5General transcription factor IIH subunit 5. (71 aa)
GTF2H1General transcription factor IIH subunit 1. (548 aa)
LOC106996511-2Histone H4. (103 aa)
HIST1H3DHistone cluster 1, H3d. (136 aa)
LOC704104Histone domain-containing protein. (154 aa)
LOC106995531Histone H2A-Bbd type 2/3-like. (115 aa)
LOC696506Histone H2B; Belongs to the histone H2B family. (126 aa)
GTF2H3General transcription factor IIH subunit 3. (308 aa)
H2BE1Histone H2B; Belongs to the histone H2B family. (122 aa)
HDAC2Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (488 aa)
UBTFNucleolar transcription factor 1 isoform a. (764 aa)
POLR2FUncharacterized protein. (179 aa)
LOC114669830Histone H3; Belongs to the histone H3 family. (136 aa)
GTF2H2General transcription factor IIH subunit. (399 aa)
H2BC5Histone H2B; Belongs to the histone H2B family. (126 aa)
TAF1BTATA-box binding protein associated factor, RNA polymerase I subunit B. (590 aa)
LOC710748Histone H3; Belongs to the histone H3 family. (136 aa)
CCNHCyclin H; Belongs to the cyclin family. (331 aa)
HIST1H2ACHistone H2A; Belongs to the histone H2A family. (130 aa)
TBPTATA-box binding protein. (326 aa)
LOC106996511Histone H4. (103 aa)
H2AFZHistone H2A; Belongs to the histone H2A family. (128 aa)
ERCC2TFIIH basal transcription factor complex helicase XPD subunit isoform 1. (760 aa)
POLR2ERNA polymerase II subunit E. (160 aa)
MNAT1CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (309 aa)
POLR2HRNA polymerase II subunit H. (175 aa)
H2AFXHistone H2A; Belongs to the histone H2A family. (143 aa)
MBD2Methyl-CpG binding domain protein 2. (412 aa)
LOC699317Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
TTF1Transcription termination factor 1. (916 aa)
F7GDN6_MACMUProtein kinase domain-containing protein. (165 aa)
F6PS34_MACMUHistone H2A; Belongs to the histone H2A family. (169 aa)
F7C6W4_MACMUHistone H2A; Belongs to the histone H2A family. (166 aa)
LOC714001Histone H2B; Belongs to the histone H2B family. (126 aa)
POLR1CDNA-directed RNA polymerases I and III subunit RPAC1. (346 aa)
SIN3BSIN3 transcription regulator family member B. (1159 aa)
HIST1H2BAHistone H2B; Belongs to the histone H2B family. (127 aa)
SAP130Sin3A associated protein 130. (1083 aa)
SUDS3Sin3 histone deacetylase corepressor complex component SDS3. (328 aa)
BAZ2ABromodomain adjacent to zinc finger domain 2A. (1910 aa)
CDK7Cyclin-dependent kinase 7; Belongs to the protein kinase superfamily. (346 aa)
H2AFJHistone H2A; Belongs to the histone H2A family. (129 aa)
H2BC15Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC695427Histone H3.1. (136 aa)
GTF2H4General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (462 aa)
H2AFVHistone H2A; Belongs to the histone H2A family. (138 aa)
HIST1H2BKHistone H2B; Belongs to the histone H2B family. (126 aa)
TAF1CTATA-box binding protein associated factor, RNA polymerase I subunit C. (843 aa)
HIST1H2BOHistone H2B; Belongs to the histone H2B family. (126 aa)
TAF1DUncharacterized protein. (312 aa)
LOC697721Histone H4. (103 aa)
LOC100430668Histone H3.1. (136 aa)
LOC699110Histone H4. (103 aa)
LOC695323Histone H4. (103 aa)
CD3EAPCD3e molecule associated protein. (515 aa)
SMARCA5SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5. (1052 aa)
LOC695427-2Histone H3; Belongs to the histone H3 family. (136 aa)
H2BU1Histone H2B; Belongs to the histone H2B family. (126 aa)
H2AC20Histone H2A; Belongs to the histone H2A family. (129 aa)
SAP30Histone deacetylase complex subunit SAP30. (220 aa)
LOC708899Histone H3.3. (136 aa)
LOC693887Histone H3.3. (136 aa)
SAP30BPSAP30 binding protein. (335 aa)
LOC703889Histone H3.1. (136 aa)
LOC704341Histone H4. (103 aa)
LOC106996511-6Histone H4. (103 aa)
LOC698354Histone H4. (103 aa)
LOC718280Histone domain-containing protein. (136 aa)
HIST1H2BJHistone H2B; Belongs to the histone H2B family. (126 aa)
BAZ2BBromodomain adjacent to zinc finger domain 2B. (2242 aa)
ARID4BAT-rich interaction domain 4B. (1318 aa)
TAF1ATATA-box binding protein associated factor, RNA polymerase I subunit A. (451 aa)
SMARCA1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1. (1070 aa)
SIN3ASIN3 transcription regulator family member A. (1273 aa)
TTLDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1135 aa)
H2AFB3Histone H2A; Belongs to the histone H2A family. (115 aa)
TWISTNBDNA-directed RNA polymerase I subunit RPA43. (337 aa)
SAP18Histone deacetylase complex subunit SAP18. (172 aa)
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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