40 items (Macaca mulatta) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	THAP6	THAP domain containing 6. (282 aa)
	GNB2	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2. (340 aa)
	AQP4	Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (348 aa)
	GNG11	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa)
	GNG3	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (152 aa)
	ADCY5	Adenylate cyclase 5. (1263 aa)
	ADCY9	Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1372 aa)
	RAB11FIP2	RAB11 family interacting protein 2. (512 aa)
	GNG7	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
	GNB1	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1. (340 aa)
	ADCY6	Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1243 aa)
	GNG4	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (71 aa)
	RAB11FIP1	RAB11 family interacting protein 1. (1275 aa)
	ADCY1	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1118 aa)
	PRKAR2A	Protein kinase cAMP-dependent type II regulatory subunit alpha. (404 aa)
	GNG13	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (67 aa)
	AQP3	Aquaporin-3; Belongs to the MIP/aquaporin (TC 1.A.8) family. (292 aa)
	GNB4	Guanine nucleotide-binding protein subunit beta-4. (340 aa)
	GNB3	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3. (340 aa)
	AVPR2	Vasopressin V2 receptor; Involved in renal water reabsorption. Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (368 aa)
	PRKACB	cAMP-dependent protein kinase catalytic subunit beta isoform 1; Belongs to the protein kinase superfamily. (398 aa)
	ADCY2	Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1091 aa)
	MYO5B	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1849 aa)
	AQP2	Aquaporin-2; Belongs to the MIP/aquaporin (TC 1.A.8) family. (271 aa)
	PRKACA	Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (431 aa)
	CNBD2	Cyclic nucleotide binding domain containing 2. (532 aa)
	LOC694289	Uncharacterized protein. (394 aa)
	PRKAR2B	Protein kinase cAMP-dependent type II regulatory subunit beta. (421 aa)
	GNB5	G protein subunit beta 5. (395 aa)
	PRKACG	cAMP-dependent protein kinase catalytic subunit gamma; Phosphorylates a large number of substrates in the cytoplasm and the nucleus; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cAMP subfamily. (350 aa)
	THAP7	THAP domain-containing protein 7 isoform 2. (309 aa)
	ADCY4	Adenylate cyclase 4. (1299 aa)
	GNG5	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
	ADCY8	Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1251 aa)
	GNGT1	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
	ADCY3	Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1145 aa)
	AVP	Arginine vasopressin; Belongs to the vasopressin/oxytocin family. (164 aa)
	ADCY7	Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1112 aa)
	PRKAR1B	Cyclic nucleotide-binding domain-containing protein. (494 aa)
	PRKAR1A	Protein kinase cAMP-dependent type I regulatory subunit alpha. (381 aa)

Your Current Organism:

Macaca mulatta

NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADCY1	ADCY2	ENSMMUP00000069811	ENSMMUP00000059741	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.486
ADCY1	ADCY3	ENSMMUP00000069811	ENSMMUP00000049332	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.945
ADCY1	ADCY4	ENSMMUP00000069811	ENSMMUP00000027242	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase 4.	0.468
ADCY1	ADCY5	ENSMMUP00000069811	ENSMMUP00000052487	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase 5.	0.457
ADCY1	ADCY6	ENSMMUP00000069811	ENSMMUP00000064485	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.441
ADCY1	ADCY7	ENSMMUP00000069811	ENSMMUP00000075019	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.509
ADCY1	ADCY8	ENSMMUP00000069811	ENSMMUP00000044242	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.951
ADCY1	ADCY9	ENSMMUP00000069811	ENSMMUP00000068875	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.663
ADCY1	GNB1	ENSMMUP00000069811	ENSMMUP00000066781	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1.	0.798
ADCY1	GNB2	ENSMMUP00000069811	ENSMMUP00000071351	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2.	0.789
ADCY1	GNB3	ENSMMUP00000069811	ENSMMUP00000006868	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3.	0.787
ADCY1	GNB4	ENSMMUP00000069811	ENSMMUP00000005459	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein subunit beta-4.	0.798
ADCY1	GNB5	ENSMMUP00000069811	ENSMMUP00000022869	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	G protein subunit beta 5.	0.838
ADCY1	GNG11	ENSMMUP00000069811	ENSMMUP00000051134	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.810
ADCY1	GNG13	ENSMMUP00000069811	ENSMMUP00000001138	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.850
ADCY1	GNG3	ENSMMUP00000069811	ENSMMUP00000051192	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.816
ADCY1	GNG4	ENSMMUP00000069811	ENSMMUP00000064430	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.573
ADCY1	GNG5	ENSMMUP00000069811	ENSMMUP00000029198	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.833
ADCY1	GNG7	ENSMMUP00000069811	ENSMMUP00000068383	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.838
ADCY1	GNGT1	ENSMMUP00000069811	ENSMMUP00000048892	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.810