28 items (Macaca mulatta) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	AKT3	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
	CDH5	Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins. (785 aa)
	CTNND1	Uncharacterized protein. (968 aa)
	MAPKAP1	Target of rapamycin complex 2 subunit MAPKAP1 isoform 1. (522 aa)
	VAV1	Vav guanine nucleotide exchange factor 1. (928 aa)
	AKT2	AKT serine/threonine kinase 2. (594 aa)
	CAV3	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (196 aa)
	AKT1	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
	CTNNB1	Catenin beta-1. (781 aa)
	VAV3	Vav guanine nucleotide exchange factor 3. (1128 aa)
	MTOR	Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2541 aa)
	STX7	Syntaxin-7; Belongs to the syntaxin family. (261 aa)
	PAK3	Uncharacterized protein. (580 aa)
	HSP90AA1	HATPase_c domain-containing protein. (733 aa)
	RICTOR	RPTOR independent companion of MTOR complex 2. (1732 aa)
	PRR5	Uncharacterized protein. (379 aa)
	F7B371_MACMU	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (313 aa)
	PDPK1	3-phosphoinositide dependent protein kinase 1. (557 aa)
	PAK2	Non-specific serine/threonine protein kinase. (524 aa)
	TRIB3	Tribbles pseudokinase 3. (385 aa)
	JUP	Uncharacterized protein. (744 aa)
	CAV1	Caveolin 1. (303 aa)
	ARVCF	ARVCF delta catenin family member. (1060 aa)
	VAV2	Guanine nucleotide exchange factor VAV2 isoform 1. (878 aa)
	CTNNA1	Uncharacterized protein. (906 aa)
	PAK1	Non-specific serine/threonine protein kinase. (575 aa)
	MLST8	MTOR associated protein, LST8 homolog. (479 aa)
	NOS3	Nitric oxide synthase; Produces nitric oxide (NO). (1205 aa)

Your Current Organism:

Macaca mulatta

NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AKT1	AKT2	ENSMMUP00000061388	ENSMMUP00000059674	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	AKT serine/threonine kinase 2.	0.968
AKT1	AKT3	ENSMMUP00000061388	ENSMMUP00000026292	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.936
AKT1	CAV1	ENSMMUP00000061388	ENSMMUP00000018556	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Caveolin 1.	0.539
AKT1	CTNNB1	ENSMMUP00000061388	ENSMMUP00000062910	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Catenin beta-1.	0.800
AKT1	F7B371_MACMU	ENSMMUP00000061388	ENSMMUP00000015037	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.845
AKT1	HSP90AA1	ENSMMUP00000061388	ENSMMUP00000080725	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	HATPase_c domain-containing protein.	0.990
AKT1	JUP	ENSMMUP00000061388	ENSMMUP00000017143	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.531
AKT1	MAPKAP1	ENSMMUP00000061388	ENSMMUP00000038842	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Target of rapamycin complex 2 subunit MAPKAP1 isoform 1.	0.818
AKT1	MLST8	ENSMMUP00000061388	ENSMMUP00000025274	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	MTOR associated protein, LST8 homolog.	0.753
AKT1	MTOR	ENSMMUP00000061388	ENSMMUP00000073444	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family.	0.994
AKT1	NOS3	ENSMMUP00000061388	ENSMMUP00000026905	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Nitric oxide synthase; Produces nitric oxide (NO).	0.979
AKT1	PAK1	ENSMMUP00000061388	ENSMMUP00000024698	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase.	0.781
AKT1	PAK3	ENSMMUP00000061388	ENSMMUP00000078285	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.463
AKT1	PDPK1	ENSMMUP00000061388	ENSMMUP00000015038	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	3-phosphoinositide dependent protein kinase 1.	0.983
AKT1	RICTOR	ENSMMUP00000061388	ENSMMUP00000002157	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	RPTOR independent companion of MTOR complex 2.	0.899
AKT1	TRIB3	ENSMMUP00000061388	ENSMMUP00000016534	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Tribbles pseudokinase 3.	0.986
AKT1	VAV1	ENSMMUP00000061388	ENSMMUP00000058900	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Vav guanine nucleotide exchange factor 1.	0.687
AKT1	VAV2	ENSMMUP00000061388	ENSMMUP00000022644	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Guanine nucleotide exchange factor VAV2 isoform 1.	0.479
AKT1	VAV3	ENSMMUP00000061388	ENSMMUP00000073333	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Vav guanine nucleotide exchange factor 3.	0.586
AKT2	AKT1	ENSMMUP00000059674	ENSMMUP00000061388	AKT serine/threonine kinase 2.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.968