STRINGSTRING
CREBBP CREBBP KRAS KRAS PAK2 PAK2 RELB RELB ICAM2 ICAM2 ERAS ERAS PAK1 PAK1 PRKACG PRKACG HRAS HRAS CD209 CD209 NFKB1 NFKB1 RPS6KA5 RPS6KA5 NRAS NRAS CCDC71L CCDC71L LYN LYN PRKACA PRKACA RELA RELA RAF1 RAF1 PRKACB PRKACB EP300 EP300 PAK3 PAK3 FYN FYN
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CREBBPCREB-binding protein isoform a. (2442 aa)
KRASKRAS proto-oncogene, GTPase. (412 aa)
PAK2Non-specific serine/threonine protein kinase. (524 aa)
RELBRELB proto-oncogene, NF-kB subunit. (574 aa)
ICAM2ICAM_N domain-containing protein. (275 aa)
ERASGTPase ERas. (233 aa)
PAK1Non-specific serine/threonine protein kinase. (575 aa)
PRKACGcAMP-dependent protein kinase catalytic subunit gamma; Phosphorylates a large number of substrates in the cytoplasm and the nucleus; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cAMP subfamily. (350 aa)
HRASTransforming protein p21. (189 aa)
CD209CD209 antigen; Pathogen-recognition receptor expressed on the surface of immature dendritic cells (DCs) and involved in initiation of primary immune response. Thought to mediate the endocytosis of pathogens which are subsequently degraded in lysosomal compartments. The receptor returns to the cell membrane surface and the pathogen-derived antigens are presented to resting T-cells via MHC class II proteins to initiate the adaptive immune response. Probably recognizes in a calcium- dependent manner high mannose N-linked oligosaccharides in a variety of pathogen antigens (By similarity). (444 aa)
NFKB1Uncharacterized protein. (977 aa)
RPS6KA5Ribosomal protein S6 kinase. (802 aa)
NRASNRAS proto-oncogene, GTPase. (189 aa)
CCDC71LCoiled-coil domain containing 71 like. (235 aa)
LYNTyrosine-protein kinase. (577 aa)
PRKACAProtein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (431 aa)
RELARELA proto-oncogene, NF-kB subunit. (544 aa)
RAF1Uncharacterized protein. (668 aa)
PRKACBcAMP-dependent protein kinase catalytic subunit beta isoform 1; Belongs to the protein kinase superfamily. (398 aa)
EP300Histone acetyltransferase p300. (2414 aa)
PAK3Uncharacterized protein. (580 aa)
FYNTyrosine-protein kinase. (589 aa)
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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