22 items (Macaca mulatta) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CREBBP	CREB-binding protein isoform a. (2442 aa)
	KRAS	KRAS proto-oncogene, GTPase. (412 aa)
	PAK2	Non-specific serine/threonine protein kinase. (524 aa)
	RELB	RELB proto-oncogene, NF-kB subunit. (574 aa)
	ICAM2	ICAM_N domain-containing protein. (275 aa)
	ERAS	GTPase ERas. (233 aa)
	PAK1	Non-specific serine/threonine protein kinase. (575 aa)
	PRKACG	cAMP-dependent protein kinase catalytic subunit gamma; Phosphorylates a large number of substrates in the cytoplasm and the nucleus; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cAMP subfamily. (350 aa)
	HRAS	Transforming protein p21. (189 aa)
	CD209	CD209 antigen; Pathogen-recognition receptor expressed on the surface of immature dendritic cells (DCs) and involved in initiation of primary immune response. Thought to mediate the endocytosis of pathogens which are subsequently degraded in lysosomal compartments. The receptor returns to the cell membrane surface and the pathogen-derived antigens are presented to resting T-cells via MHC class II proteins to initiate the adaptive immune response. Probably recognizes in a calcium- dependent manner high mannose N-linked oligosaccharides in a variety of pathogen antigens (By similarity). (444 aa)
	NFKB1	Uncharacterized protein. (977 aa)
	RPS6KA5	Ribosomal protein S6 kinase. (802 aa)
	NRAS	NRAS proto-oncogene, GTPase. (189 aa)
	CCDC71L	Coiled-coil domain containing 71 like. (235 aa)
	LYN	Tyrosine-protein kinase. (577 aa)
	PRKACA	Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (431 aa)
	RELA	RELA proto-oncogene, NF-kB subunit. (544 aa)
	RAF1	Uncharacterized protein. (668 aa)
	PRKACB	cAMP-dependent protein kinase catalytic subunit beta isoform 1; Belongs to the protein kinase superfamily. (398 aa)
	EP300	Histone acetyltransferase p300. (2414 aa)
	PAK3	Uncharacterized protein. (580 aa)
	FYN	Tyrosine-protein kinase. (589 aa)

Your Current Organism:

Macaca mulatta

NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CD209	ICAM2	ENSMMUP00000029559	ENSMMUP00000019231	CD209 antigen; Pathogen-recognition receptor expressed on the surface of immature dendritic cells (DCs) and involved in initiation of primary immune response. Thought to mediate the endocytosis of pathogens which are subsequently degraded in lysosomal compartments. The receptor returns to the cell membrane surface and the pathogen-derived antigens are presented to resting T-cells via MHC class II proteins to initiate the adaptive immune response. Probably recognizes in a calcium- dependent manner high mannose N-linked oligosaccharides in a variety of pathogen antigens (By similarity).	ICAM_N domain-containing protein.	0.927
CREBBP	EP300	ENSMMUP00000065708	ENSMMUP00000076664	CREB-binding protein isoform a.	Histone acetyltransferase p300.	0.998
CREBBP	NFKB1	ENSMMUP00000065708	ENSMMUP00000034946	CREB-binding protein isoform a.	Uncharacterized protein.	0.758
CREBBP	PRKACA	ENSMMUP00000065708	ENSMMUP00000054168	CREB-binding protein isoform a.	Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily.	0.814
CREBBP	PRKACB	ENSMMUP00000065708	ENSMMUP00000059748	CREB-binding protein isoform a.	cAMP-dependent protein kinase catalytic subunit beta isoform 1; Belongs to the protein kinase superfamily.	0.806
CREBBP	PRKACG	ENSMMUP00000065708	ENSMMUP00000026815	CREB-binding protein isoform a.	cAMP-dependent protein kinase catalytic subunit gamma; Phosphorylates a large number of substrates in the cytoplasm and the nucleus; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cAMP subfamily.	0.813
CREBBP	RELA	ENSMMUP00000065708	ENSMMUP00000054901	CREB-binding protein isoform a.	RELA proto-oncogene, NF-kB subunit.	0.981
CREBBP	RELB	ENSMMUP00000065708	ENSMMUP00000018596	CREB-binding protein isoform a.	RELB proto-oncogene, NF-kB subunit.	0.734
EP300	CREBBP	ENSMMUP00000076664	ENSMMUP00000065708	Histone acetyltransferase p300.	CREB-binding protein isoform a.	0.998
EP300	NFKB1	ENSMMUP00000076664	ENSMMUP00000034946	Histone acetyltransferase p300.	Uncharacterized protein.	0.884
EP300	PRKACA	ENSMMUP00000076664	ENSMMUP00000054168	Histone acetyltransferase p300.	Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily.	0.685
EP300	PRKACB	ENSMMUP00000076664	ENSMMUP00000059748	Histone acetyltransferase p300.	cAMP-dependent protein kinase catalytic subunit beta isoform 1; Belongs to the protein kinase superfamily.	0.713
EP300	PRKACG	ENSMMUP00000076664	ENSMMUP00000026815	Histone acetyltransferase p300.	cAMP-dependent protein kinase catalytic subunit gamma; Phosphorylates a large number of substrates in the cytoplasm and the nucleus; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cAMP subfamily.	0.685
EP300	RELA	ENSMMUP00000076664	ENSMMUP00000054901	Histone acetyltransferase p300.	RELA proto-oncogene, NF-kB subunit.	0.961
EP300	RELB	ENSMMUP00000076664	ENSMMUP00000018596	Histone acetyltransferase p300.	RELB proto-oncogene, NF-kB subunit.	0.722
ERAS	FYN	ENSMMUP00000021640	ENSMMUP00000080137	GTPase ERas.	Tyrosine-protein kinase.	0.418
ERAS	HRAS	ENSMMUP00000021640	ENSMMUP00000028522	GTPase ERas.	Transforming protein p21.	0.513
ERAS	LYN	ENSMMUP00000021640	ENSMMUP00000052162	GTPase ERas.	Tyrosine-protein kinase.	0.475
ERAS	PAK1	ENSMMUP00000021640	ENSMMUP00000024698	GTPase ERas.	Non-specific serine/threonine protein kinase.	0.485
ERAS	PAK2	ENSMMUP00000021640	ENSMMUP00000015786	GTPase ERas.	Non-specific serine/threonine protein kinase.	0.412