STRINGSTRING
DSTN DSTN RHOA RHOA ROCK1 ROCK1 MYL6 MYL6 MYH9 MYH9 CFL1 CFL1 MYH10 MYH10 ENSMMUP00000075429 ENSMMUP00000075429 CFL2 CFL2 LIMK2 LIMK2 MYL9 MYL9 MYH14 MYH14 PAK1 PAK1 PPP1R12A PPP1R12A PPP1R12B PPP1R12B PPP1CB PPP1CB ROCK2 ROCK2 LIMK1 LIMK1 MYH11 MYH11
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DSTNDestrin, actin depolymerizing factor; Belongs to the actin-binding proteins ADF family. (165 aa)
RHOARas homolog family member A. (209 aa)
ROCK1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1354 aa)
MYL6Myosin light chain 6. (160 aa)
MYH9Myosin heavy chain 9; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1981 aa)
CFL1ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (177 aa)
MYH10Myosin heavy chain 10; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2007 aa)
ENSMMUP00000075429Uncharacterized protein. (115 aa)
CFL2Cofilin-2; Belongs to the actin-binding proteins ADF family. (166 aa)
LIMK2LIM domain kinase 2. (793 aa)
MYL9Myosin regulatory light polypeptide 9 isoform a. (172 aa)
MYH14Myosin heavy chain 14; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2035 aa)
PAK1Non-specific serine/threonine protein kinase. (575 aa)
PPP1R12AProtein phosphatase 1 regulatory subunit. (1029 aa)
PPP1R12BProtein phosphatase 1 regulatory subunit. (1090 aa)
PPP1CBSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (339 aa)
ROCK2Uncharacterized protein; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1474 aa)
LIMK1LIM domain kinase 1 isoform 1. (647 aa)
MYH11Myosin heavy chain 11; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2139 aa)
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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