STRINGSTRING
VWA5B2 VWA5B2 MEIOB MEIOB RPA3 RPA3 SUMO3-2 SUMO3-2 USP45 USP45 NFATC2IP NFATC2IP CHD1L CHD1L CUL4B CUL4B PIAS1 PIAS1 CETN2 CETN2 UBE2V2 UBE2V2 XPA XPA RPS27A RPS27A RPS27A-2 RPS27A-2 ERCC4 ERCC4 UBA52 UBA52 VTCN1 VTCN1 CDK7 CDK7 CUL4A CUL4A VWA5A VWA5A F7DM39_MACMU F7DM39_MACMU PARP1 PARP1 PARP3 PARP3 WDR76 WDR76 RNF111 RNF111 KCTD2 KCTD2 BIVM BIVM F7GDN6_MACMU F7GDN6_MACMU RAD23B RAD23B RPA1 RPA1 KXD1 KXD1 MNAT1 MNAT1 XPC XPC SUMO1 SUMO1 UBC UBC ERCC2 ERCC2 CCNH CCNH UBB UBB ERCC1 ERCC1 UBE2N UBE2N SUMO3 SUMO3 GTF2H2 GTF2H2 RBX1 RBX1 RAD23A RAD23A GTF2H3 GTF2H3 ENSMMUP00000058534 ENSMMUP00000058534 CETN3 CETN3 GTF2H1 GTF2H1 GTF2H5 GTF2H5 UBE2I UBE2I ERCC3 ERCC3 ENSMMUP00000067421 ENSMMUP00000067421 ENSMMUP00000069269 ENSMMUP00000069269 DDB1 DDB1 ENSMMUP00000070235 ENSMMUP00000070235 ENSMMUP00000072025 ENSMMUP00000072025 LOC699185 LOC699185 JPT1 JPT1 PARP2 PARP2 ENSMMUP00000079481 ENSMMUP00000079481 GTF2H4 GTF2H4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
VWA5B2Von Willebrand factor A domain-containing protein 5B2. (1243 aa)
MEIOBMeiosis specific with OB-fold. (550 aa)
RPA3Replication protein A 14 kDa subunit. (121 aa)
SUMO3-2Ubiquitin-like domain-containing protein. (146 aa)
USP45Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (815 aa)
NFATC2IPNuclear factor of activated T cells 2 interacting protein. (441 aa)
CHD1LChromodomain-helicase-DNA-binding protein 1-like. (900 aa)
CUL4BCullin 4B; Belongs to the cullin family. (933 aa)
PIAS1Protein inhibitor of activated STAT protein 1. (651 aa)
CETN2Centrin-2. (172 aa)
UBE2V2Ubiquitin-conjugating enzyme E2 variant 2. (145 aa)
XPAXPA, DNA damage recognition and repair factor. (294 aa)
RPS27AUncharacterized protein. (156 aa)
RPS27A-2Ubiquitin-40S ribosomal protein S27a. (156 aa)
ERCC4ERCC excision repair 4, endonuclease catalytic subunit. (916 aa)
UBA52Ubiquitin-60S ribosomal protein L40. (128 aa)
VTCN1V-set domain containing T cell activation inhibitor 1. (282 aa)
CDK7Cyclin-dependent kinase 7; Belongs to the protein kinase superfamily. (346 aa)
CUL4ACullin 4A; Belongs to the cullin family. (759 aa)
VWA5AVon Willebrand factor A domain containing 5A. (813 aa)
F7DM39_MACMUUncharacterized protein. (143 aa)
PARP1Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1014 aa)
PARP3Poly [ADP-ribose] polymerase. (532 aa)
WDR76WD repeat-containing protein 76; Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC. Belongs to the WD repeat DDB2/WDR76 family. (625 aa)
RNF111Ring finger protein 111. (1041 aa)
KCTD2Potassium channel tetramerization domain containing 2. (268 aa)
BIVMBIVM-ERCC5 readthrough. (1636 aa)
F7GDN6_MACMUProtein kinase domain-containing protein. (165 aa)
RAD23BRAD23 homolog B, nucleotide excision repair protein. (409 aa)
RPA1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (616 aa)
KXD1KxDL domain-containing protein. (231 aa)
MNAT1CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (309 aa)
XPCXPC complex subunit, DNA damage recognition and repair factor. (994 aa)
SUMO1Small ubiquitin-related modifier. (101 aa)
UBCUncharacterized protein. (270 aa)
ERCC2TFIIH basal transcription factor complex helicase XPD subunit isoform 1. (760 aa)
CCNHCyclin H; Belongs to the cyclin family. (331 aa)
UBBUncharacterized protein. (229 aa)
ERCC1ERCC excision repair 1, endonuclease non-catalytic subunit. (442 aa)
UBE2NUBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (210 aa)
SUMO3Ubiquitin-like domain-containing protein. (138 aa)
GTF2H2General transcription factor IIH subunit. (399 aa)
RBX1E3 ubiquitin-protein ligase RBX1. (108 aa)
RAD23ARAD23 homolog A, nucleotide excision repair protein. (363 aa)
GTF2H3General transcription factor IIH subunit 3. (308 aa)
ENSMMUP00000058534UBIQUITIN_CONJUGAT_2 domain-containing protein. (145 aa)
CETN3Uncharacterized protein. (191 aa)
GTF2H1General transcription factor IIH subunit 1. (548 aa)
GTF2H5General transcription factor IIH subunit 5. (71 aa)
UBE2IUBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (260 aa)
ERCC3TFIIH basal transcription factor complex helicase XPB subunit. (782 aa)
ENSMMUP00000067421Ubiquitin-like domain-containing protein. (135 aa)
ENSMMUP00000069269Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (437 aa)
DDB1Damage specific DNA binding protein 1. (1147 aa)
ENSMMUP00000070235Ubiquitin-like domain-containing protein. (110 aa)
ENSMMUP00000072025Small ubiquitin-related modifier. (101 aa)
LOC699185Small ubiquitin-related modifier. (101 aa)
JPT1Ubiquitin-like domain-containing protein. (359 aa)
PARP2Poly [ADP-ribose] polymerase. (570 aa)
ENSMMUP00000079481Uncharacterized protein. (156 aa)
GTF2H4General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (462 aa)
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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