STRINGSTRING
CCNH CCNH POLR2I POLR2I MEIOB MEIOB RPA3 RPA3 INO80D INO80D POLE4 POLE4 POLR2D POLR2D SUMO3-2 SUMO3-2 WBP1 WBP1 INO80B INO80B PPP1R42 PPP1R42 RFC3 RFC3 ACTR5 ACTR5 RFC4 RFC4 RFC2 RFC2 POLE2 POLE2 USP7 USP7 XRCC1 XRCC1 LIG3 LIG3 USP40 USP40 USP45 USP45 HMGN1 HMGN1 COPS5 COPS5 ZNF830 ZNF830 NFATC2IP NFATC2IP CHD1L CHD1L CUL4B CUL4B LOC705671 LOC705671 COPS7A COPS7A ACTL6A ACTL6A RFC5 RFC5 NRDE2 NRDE2 MCRS1 MCRS1 ISY1 ISY1 PIAS1 PIAS1 CETN2 CETN2 POLR2J POLR2J UBE2V2 UBE2V2 XPA XPA COPS6 COPS6 RPS27A RPS27A POLR2B POLR2B POLR2G POLR2G PRPF19 PRPF19 POLE POLE RPS27A-2 RPS27A-2 ERCC4 ERCC4 UBA52 UBA52 VTCN1 VTCN1 PHF3 PHF3 ERCC6 ERCC6 CDK7 CDK7 PPIE PPIE TCEA2 TCEA2 VWA5B2 VWA5B2 ACTR8 ACTR8 CUL4A CUL4A INO80C INO80C INO80E INO80E VWA5A VWA5A POLD3 POLD3 F7DM39_MACMU F7DM39_MACMU ERCC8 ERCC8 PARP1 PARP1 PARP3 PARP3 TFPT TFPT COPS4 COPS4 WDR76 WDR76 YY1 YY1 RNF111 RNF111 KCTD2 KCTD2 POLK POLK BIVM BIVM F7GDN6_MACMU F7GDN6_MACMU RUVBL1 RUVBL1 RAD23B RAD23B RPAP3 RPAP3 TCEANC2 TCEANC2 SPOCD1 SPOCD1 RPA1 RPA1 KXD1 KXD1 POLR2H POLR2H MNAT1 MNAT1 XPC XPC ACTG1 ACTG1 GPS1 GPS1 COPS8 COPS8 POLR2E POLR2E SUMO1 SUMO1 TCEA3 TCEA3 UBC UBC ERCC2 ERCC2 POLE3 POLE3 TCEA1 TCEA1 ATAD5 ATAD5 UBB UBB ERCC1 ERCC1 UBE2N UBE2N COPS2 COPS2 COPS3 COPS3 ACTB ACTB RCBTB1 RCBTB1 SUMO3 SUMO3 ELL ELL GTF2H2 GTF2H2 NFRKB NFRKB ENSMMUP00000056331 ENSMMUP00000056331 RBX1 RBX1 RCBTB2 RCBTB2 POLR2F POLR2F RFC1 RFC1 RAD23A RAD23A COPS7B COPS7B GTF2H3 GTF2H3 ENSMMUP00000058534 ENSMMUP00000058534 CETN3 CETN3 POLR2A POLR2A HMGN1-2 HMGN1-2 PCNA PCNA LOC699342 LOC699342 GTF2H1 GTF2H1 GTF2H5 GTF2H5 YY2 YY2 ZFP42 ZFP42 UBE2I UBE2I ERCC3 ERCC3 ENSMMUP00000067421 ENSMMUP00000067421 POLD1 POLD1 XAB2 XAB2 TCEANC TCEANC ENSMMUP00000069269 ENSMMUP00000069269 DDB1 DDB1 UVSSA UVSSA LIG1 LIG1 ENSMMUP00000070235 ENSMMUP00000070235 INO80 INO80 ENSMMUP00000072025 ENSMMUP00000072025 LOC699185 LOC699185 JPT1 JPT1 POLR2C POLR2C AQR AQR ENSMMUP00000076576 ENSMMUP00000076576 EP300 EP300 ENSMMUP00000077297 ENSMMUP00000077297 UPK3BL2 UPK3BL2 PARP2 PARP2 LOC114669758 LOC114669758 ENSMMUP00000079481 ENSMMUP00000079481 POLD2 POLD2 GTF2H4 GTF2H4 POLD4 POLD4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CCNHCyclin H; Belongs to the cyclin family. (331 aa)
POLR2IDNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (125 aa)
MEIOBMeiosis specific with OB-fold. (550 aa)
RPA3Replication protein A 14 kDa subunit. (121 aa)
INO80DINO80 complex subunit D. (1027 aa)
POLE4DNA polymerase epsilon subunit 4. (117 aa)
POLR2DDNA-directed RNA polymerase II subunit RPB4. (142 aa)
SUMO3-2Ubiquitin-like domain-containing protein. (146 aa)
WBP1WW domain-binding protein 1. (269 aa)
INO80BINO80 complex subunit B. (356 aa)
PPP1R42Protein phosphatase 1 regulatory subunit 42. (357 aa)
RFC3Replication factor C subunit 3 isoform 1. (356 aa)
ACTR5Actin related protein 5; Belongs to the actin family. (607 aa)
RFC4Replication factor C subunit 4. (363 aa)
RFC2Replication factor C subunit 2. (233 aa)
POLE2DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (527 aa)
USP7Ubiquitin carboxyl-terminal hydrolase 7; Belongs to the peptidase C19 family. (1102 aa)
XRCC1X-ray repair cross complementing 1. (633 aa)
LIG3DNA ligase. (1020 aa)
USP40Ubiquitin specific peptidase 40; Belongs to the peptidase C19 family. (1242 aa)
USP45Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (815 aa)
HMGN1Uncharacterized protein. (94 aa)
COPS5COP9 signalosome complex subunit 5. (334 aa)
ZNF830Zinc finger protein 830. (372 aa)
NFATC2IPNuclear factor of activated T cells 2 interacting protein. (441 aa)
CHD1LChromodomain-helicase-DNA-binding protein 1-like. (900 aa)
CUL4BCullin 4B; Belongs to the cullin family. (933 aa)
LOC705671Uncharacterized protein. (398 aa)
COPS7ACOP9 signalosome complex subunit 7a. (275 aa)
ACTL6AActin-like protein 6A isoform 1; Belongs to the actin family. (429 aa)
RFC5Replication factor C subunit 5 isoform 1. (340 aa)
NRDE2Uncharacterized protein. (1164 aa)
MCRS1Microspherule protein 1. (475 aa)
ISY1Uncharacterized protein. (408 aa)
PIAS1Protein inhibitor of activated STAT protein 1. (651 aa)
CETN2Centrin-2. (172 aa)
POLR2JDNA-directed RNA polymerase II subunit RPB11-a. (117 aa)
UBE2V2Ubiquitin-conjugating enzyme E2 variant 2. (145 aa)
XPAXPA, DNA damage recognition and repair factor. (294 aa)
COPS6COP9 signalosome subunit 6. (394 aa)
RPS27AUncharacterized protein. (156 aa)
POLR2BDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1174 aa)
POLR2GS1 domain-containing protein. (209 aa)
PRPF19Pre-mRNA processing factor 19. (512 aa)
POLEDNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2288 aa)
RPS27A-2Ubiquitin-40S ribosomal protein S27a. (156 aa)
ERCC4ERCC excision repair 4, endonuclease catalytic subunit. (916 aa)
UBA52Ubiquitin-60S ribosomal protein L40. (128 aa)
VTCN1V-set domain containing T cell activation inhibitor 1. (282 aa)
PHF3PHD finger protein 3. (2057 aa)
ERCC6ERCC excision repair 6, chromatin remodeling factor. (2061 aa)
CDK7Cyclin-dependent kinase 7; Belongs to the protein kinase superfamily. (346 aa)
PPIEPeptidylprolyl isomerase E. (369 aa)
TCEA2Transcription elongation factor A2. (324 aa)
VWA5B2Von Willebrand factor A domain-containing protein 5B2. (1243 aa)
ACTR8Actin-related protein 8; Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize; Belongs to the actin family. ARP8 subfamily. (624 aa)
CUL4ACullin 4A; Belongs to the cullin family. (759 aa)
INO80CYL1_C domain-containing protein. (228 aa)
INO80EUncharacterized protein. (243 aa)
VWA5AVon Willebrand factor A domain containing 5A. (813 aa)
POLD3DNA polymerase delta subunit 3. (466 aa)
F7DM39_MACMUUncharacterized protein. (143 aa)
ERCC8ERCC excision repair 8, CSA ubiquitin ligase complex subunit. (375 aa)
PARP1Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1014 aa)
PARP3Poly [ADP-ribose] polymerase. (532 aa)
TFPTTCF3 fusion partner. (253 aa)
COPS4COP9 signalosome subunit 4. (420 aa)
WDR76WD repeat-containing protein 76; Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC. Belongs to the WD repeat DDB2/WDR76 family. (625 aa)
YY1Transcriptional repressor protein YY1. (414 aa)
RNF111Ring finger protein 111. (1041 aa)
KCTD2Potassium channel tetramerization domain containing 2. (268 aa)
POLKDNA polymerase kappa. (868 aa)
BIVMBIVM-ERCC5 readthrough. (1636 aa)
F7GDN6_MACMUProtein kinase domain-containing protein. (165 aa)
RUVBL1RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (456 aa)
RAD23BRAD23 homolog B, nucleotide excision repair protein. (409 aa)
RPAP3RNA polymerase II associated protein 3. (665 aa)
TCEANC2Transcription elongation factor A N-terminal and central domain-containing protein 2. (208 aa)
SPOCD1SPOC domain containing 1. (1199 aa)
RPA1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (616 aa)
KXD1KxDL domain-containing protein. (231 aa)
POLR2HRNA polymerase II subunit H. (175 aa)
MNAT1CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (309 aa)
XPCXPC complex subunit, DNA damage recognition and repair factor. (994 aa)
ACTG1Actin, cytoplasmic 2. (375 aa)
GPS1G protein pathway suppressor 1. (555 aa)
COPS8COP9 signalosome subunit 8. (226 aa)
POLR2ERNA polymerase II subunit E. (160 aa)
SUMO1Small ubiquitin-related modifier. (101 aa)
TCEA3Transcription elongation factor A3. (348 aa)
UBCUncharacterized protein. (270 aa)
ERCC2TFIIH basal transcription factor complex helicase XPD subunit isoform 1. (760 aa)
POLE3DNA polymerase epsilon subunit 3. (147 aa)
TCEA1Transcription elongation factor A protein 1 isoform 1. (301 aa)
ATAD5ATPase family AAA domain containing 5. (1848 aa)
UBBUncharacterized protein. (229 aa)
ERCC1ERCC excision repair 1, endonuclease non-catalytic subunit. (442 aa)
UBE2NUBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (210 aa)
COPS2COP9 signalosome complex subunit 2 isoform 1. (443 aa)
COPS3COP9 signalosome complex subunit 3 isoform 1. (423 aa)
ACTBUncharacterized protein. (421 aa)
RCBTB1RCC1 and BTB domain-containing protein 1. (531 aa)
SUMO3Ubiquitin-like domain-containing protein. (138 aa)
ELLElongation factor for RNA polymerase II. (621 aa)
GTF2H2General transcription factor IIH subunit. (399 aa)
NFRKBNuclear factor related to kappaB binding protein. (1433 aa)
ENSMMUP00000056331XRCC1_N domain-containing protein. (403 aa)
RBX1E3 ubiquitin-protein ligase RBX1. (108 aa)
RCBTB2RCC1 and BTB domain containing protein 2. (556 aa)
POLR2FUncharacterized protein. (179 aa)
RFC1Replication factor C subunit 1. (1146 aa)
RAD23ARAD23 homolog A, nucleotide excision repair protein. (363 aa)
COPS7BCOP9 signalosome subunit 7B. (308 aa)
GTF2H3General transcription factor IIH subunit 3. (308 aa)
ENSMMUP00000058534UBIQUITIN_CONJUGAT_2 domain-containing protein. (145 aa)
CETN3Uncharacterized protein. (191 aa)
POLR2ADNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1970 aa)
HMGN1-2Non-histone chromosomal protein HMG-14. (100 aa)
PCNAProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
LOC699342PCI domain-containing protein. (395 aa)
GTF2H1General transcription factor IIH subunit 1. (548 aa)
GTF2H5General transcription factor IIH subunit 5. (71 aa)
YY2Uncharacterized protein. (599 aa)
ZFP42ZFP42 zinc finger protein. (312 aa)
UBE2IUBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (260 aa)
ERCC3TFIIH basal transcription factor complex helicase XPB subunit. (782 aa)
ENSMMUP00000067421Ubiquitin-like domain-containing protein. (135 aa)
POLD1DNA polymerase. (1145 aa)
XAB2Pre-mRNA-splicing factor SYF1. (855 aa)
TCEANCTranscription elongation factor A N-terminal and central domain containing. (350 aa)
ENSMMUP00000069269Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (437 aa)
DDB1Damage specific DNA binding protein 1. (1147 aa)
UVSSAUV stimulated scaffold protein A. (769 aa)
LIG1DNA ligase. (1108 aa)
ENSMMUP00000070235Ubiquitin-like domain-containing protein. (110 aa)
INO80Putative DNA helicase INO80 complex-like protein 1. (1556 aa)
ENSMMUP00000072025Small ubiquitin-related modifier. (101 aa)
LOC699185Small ubiquitin-related modifier. (101 aa)
JPT1Ubiquitin-like domain-containing protein. (359 aa)
POLR2CRNA polymerase II subunit C. (306 aa)
AQRRNA helicase aquarius; Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre- mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing. (1492 aa)
ENSMMUP00000076576Uncharacterized protein. (100 aa)
EP300Histone acetyltransferase p300. (2414 aa)
ENSMMUP00000077297Uncharacterized protein. (168 aa)
UPK3BL2Uncharacterized protein. (266 aa)
PARP2Poly [ADP-ribose] polymerase. (570 aa)
LOC114669758Actin-related protein 8; Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize; Belongs to the actin family. ARP8 subfamily. (440 aa)
ENSMMUP00000079481Uncharacterized protein. (156 aa)
POLD2DNA polymerase delta 2, accessory subunit. (536 aa)
GTF2H4General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (462 aa)
POLD4DNA polymerase delta subunit p12. (107 aa)
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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