STRINGSTRING
RPA3 RPA3 POLE4 POLE4 RFC3 RFC3 RFC4 RFC4 RFC2 RFC2 POLE2 POLE2 CHD1L CHD1L CUL4B CUL4B RFC5 RFC5 XPA XPA RPS27A RPS27A POLE POLE RPS27A-2 RPS27A-2 ERCC4 ERCC4 UBA52 UBA52 CUL4A CUL4A POLD3 POLD3 F7DM39_MACMU F7DM39_MACMU PARP1 PARP1 PARP3 PARP3 POLK POLK BIVM BIVM RPA1 RPA1 KXD1 KXD1 UBC UBC ERCC2 ERCC2 POLE3 POLE3 UBB UBB ERCC1 ERCC1 RCBTB1 RCBTB1 GTF2H2 GTF2H2 RBX1 RBX1 RCBTB2 RCBTB2 RFC1 RFC1 GTF2H3 GTF2H3 PCNA PCNA GTF2H1 GTF2H1 GTF2H5 GTF2H5 ERCC3 ERCC3 ENSMMUP00000067421 ENSMMUP00000067421 POLD1 POLD1 ENSMMUP00000069269 ENSMMUP00000069269 DDB1 DDB1 ENSMMUP00000070235 ENSMMUP00000070235 PARP2 PARP2 POLD2 POLD2 GTF2H4 GTF2H4 POLD4 POLD4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RPA3Replication protein A 14 kDa subunit. (121 aa)
POLE4DNA polymerase epsilon subunit 4. (117 aa)
RFC3Replication factor C subunit 3 isoform 1. (356 aa)
RFC4Replication factor C subunit 4. (363 aa)
RFC2Replication factor C subunit 2. (233 aa)
POLE2DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (527 aa)
CHD1LChromodomain-helicase-DNA-binding protein 1-like. (900 aa)
CUL4BCullin 4B; Belongs to the cullin family. (933 aa)
RFC5Replication factor C subunit 5 isoform 1. (340 aa)
XPAXPA, DNA damage recognition and repair factor. (294 aa)
RPS27AUncharacterized protein. (156 aa)
POLEDNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2288 aa)
RPS27A-2Ubiquitin-40S ribosomal protein S27a. (156 aa)
ERCC4ERCC excision repair 4, endonuclease catalytic subunit. (916 aa)
UBA52Ubiquitin-60S ribosomal protein L40. (128 aa)
CUL4ACullin 4A; Belongs to the cullin family. (759 aa)
POLD3DNA polymerase delta subunit 3. (466 aa)
F7DM39_MACMUUncharacterized protein. (143 aa)
PARP1Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1014 aa)
PARP3Poly [ADP-ribose] polymerase. (532 aa)
POLKDNA polymerase kappa. (868 aa)
BIVMBIVM-ERCC5 readthrough. (1636 aa)
RPA1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (616 aa)
KXD1KxDL domain-containing protein. (231 aa)
UBCUncharacterized protein. (270 aa)
ERCC2TFIIH basal transcription factor complex helicase XPD subunit isoform 1. (760 aa)
POLE3DNA polymerase epsilon subunit 3. (147 aa)
UBBUncharacterized protein. (229 aa)
ERCC1ERCC excision repair 1, endonuclease non-catalytic subunit. (442 aa)
RCBTB1RCC1 and BTB domain-containing protein 1. (531 aa)
GTF2H2General transcription factor IIH subunit. (399 aa)
RBX1E3 ubiquitin-protein ligase RBX1. (108 aa)
RCBTB2RCC1 and BTB domain containing protein 2. (556 aa)
RFC1Replication factor C subunit 1. (1146 aa)
GTF2H3General transcription factor IIH subunit 3. (308 aa)
PCNAProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
GTF2H1General transcription factor IIH subunit 1. (548 aa)
GTF2H5General transcription factor IIH subunit 5. (71 aa)
ERCC3TFIIH basal transcription factor complex helicase XPB subunit. (782 aa)
ENSMMUP00000067421Ubiquitin-like domain-containing protein. (135 aa)
POLD1DNA polymerase. (1145 aa)
ENSMMUP00000069269Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (437 aa)
DDB1Damage specific DNA binding protein 1. (1147 aa)
ENSMMUP00000070235Ubiquitin-like domain-containing protein. (110 aa)
PARP2Poly [ADP-ribose] polymerase. (570 aa)
POLD2DNA polymerase delta 2, accessory subunit. (536 aa)
GTF2H4General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (462 aa)
POLD4DNA polymerase delta subunit p12. (107 aa)
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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