STRINGSTRING
POLR2I POLR2I GTF2H4 GTF2H4 SLC39A13 SLC39A13 IWS1 IWS1 UPK3BL2 UPK3BL2 NCBP2L NCBP2L C6orf15 C6orf15 MLLT3 MLLT3 GTF2B GTF2B TAF7 TAF7 POLR2C POLR2C ELOA ELOA CDK9 CDK9 WDR61 WDR61 TBP TBP SUPT4H1 SUPT4H1 ERCC2 ERCC2 TCEA3 TCEA3 ELOB ELOB POLR2E POLR2E TAF11 TAF11 ENSMMUP00000044764 ENSMMUP00000044764 MNAT1 MNAT1 POLR2H POLR2H TAF1L TAF1L TCEANC2 TCEANC2 F7GDN6_MACMU F7GDN6_MACMU EAF1 EAF1 CCNH CCNH TCEA1 TCEA1 ELOC ELOC TAF15 TAF15 TAF6 TAF6 NCBP1 NCBP1 ELL ELL GTF2H2 GTF2H2 NELFA NELFA POLR2F POLR2F NELFCD NELFCD ENSMMUP00000058345 ENSMMUP00000058345 GTF2H3 GTF2H3 CCNK CCNK POLR2A POLR2A GTF2H1 GTF2H1 GTF2H5 GTF2H5 CINP CINP ERCC3 ERCC3 TBPL1 TBPL1 TCEANC TCEANC TAF9B TAF9B PRF1 PRF1 TAF13 TAF13 CCNT1 CCNT1 TAF12 TAF12 CDC73 CDC73 SSRP1 SSRP1 SPAG16 SPAG16 GTF2E2 GTF2E2 EAF2 EAF2 GTF2E1 GTF2E1 POLR2D POLR2D LEO1 LEO1 SUPT6H SUPT6H NELFB NELFB PAF1 PAF1 TAF1 TAF1 MLLT1 MLLT1 TAF10 TAF10 NCBP2 NCBP2 TAF4 TAF4 CTDP1 CTDP1 CTR9 CTR9 CCNQ CCNQ TAF5 TAF5 POLR2J POLR2J GTF2F2 GTF2F2 POLR2B POLR2B AFF1 AFF1 POLR2G POLR2G TAF2 TAF2 SUPT16H SUPT16H RTF1 RTF1 AFF4 AFF4 LOC106994494 LOC106994494 TAF4B TAF4B GTF2A2 GTF2A2 CDK7 CDK7 F6XRN0_MACMU F6XRN0_MACMU TCEA2 TCEA2 C14H11orf88 C14H11orf88 TAF7L TAF7L GTF2A1 GTF2A1 SUPT5H SUPT5H NELFE NELFE F7HPQ9_MACMU F7HPQ9_MACMU F7HPQ7_MACMU F7HPQ7_MACMU CCNT2 CCNT2 TAF3 TAF3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
POLR2IDNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (125 aa)
GTF2H4General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (462 aa)
SLC39A13Solute carrier family 39 member 13. (400 aa)
IWS1Interacts with SUPT6H, CTD assembly factor 1. (818 aa)
UPK3BL2Uncharacterized protein. (266 aa)
NCBP2LNuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] (153 aa)
C6orf15Uncharacterized protein C6orf15 homolog. (314 aa)
MLLT3MLLT3 super elongation complex subunit. (600 aa)
GTF2BGeneral transcription factor IIB. (312 aa)
TAF7Transcription initiation factor TFIID subunit 7. (349 aa)
POLR2CRNA polymerase II subunit C. (306 aa)
ELOAElongin A. (846 aa)
CDK9Cyclin-dependent kinase 9; Belongs to the protein kinase superfamily. (372 aa)
WDR61WD repeat domain 61. (359 aa)
TBPTATA-box binding protein. (326 aa)
SUPT4H1Transcription elongation factor SPT4; Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II; Belongs to the SPT4 family. (117 aa)
ERCC2TFIIH basal transcription factor complex helicase XPD subunit isoform 1. (760 aa)
TCEA3Transcription elongation factor A3. (348 aa)
ELOBTranscription elongation factor B polypeptide 2 isoform a. (118 aa)
POLR2ERNA polymerase II subunit E. (160 aa)
TAF11Transcription initiation factor TFIID subunit 11. (211 aa)
ENSMMUP00000044764TFIIA_gamma_C domain-containing protein. (74 aa)
MNAT1CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (309 aa)
POLR2HRNA polymerase II subunit H. (175 aa)
TAF1LTATA-box binding protein associated factor 1 like. (1776 aa)
TCEANC2Transcription elongation factor A N-terminal and central domain-containing protein 2. (208 aa)
F7GDN6_MACMUProtein kinase domain-containing protein. (165 aa)
EAF1ELL-associated factor 1. (268 aa)
CCNHCyclin H; Belongs to the cyclin family. (331 aa)
TCEA1Transcription elongation factor A protein 1 isoform 1. (301 aa)
ELOCElongin C; Belongs to the SKP1 family. (151 aa)
TAF15TATA-box binding protein associated factor 15. (575 aa)
TAF6TATA-box binding protein associated factor 6. (678 aa)
NCBP1Nuclear cap-binding protein subunit 1. (790 aa)
ELLElongation factor for RNA polymerase II. (621 aa)
GTF2H2General transcription factor IIH subunit. (399 aa)
NELFANegative elongation factor complex member A. (539 aa)
POLR2FUncharacterized protein. (179 aa)
NELFCDNegative elongation factor complex member C/D. (599 aa)
ENSMMUP00000058345TAFII28 domain-containing protein. (199 aa)
GTF2H3General transcription factor IIH subunit 3. (308 aa)
CCNKCyclin K; Belongs to the cyclin family. (580 aa)
POLR2ADNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1970 aa)
GTF2H1General transcription factor IIH subunit 1. (548 aa)
GTF2H5General transcription factor IIH subunit 5. (71 aa)
CINPCyclin dependent kinase 2 interacting protein. (212 aa)
ERCC3TFIIH basal transcription factor complex helicase XPB subunit. (782 aa)
TBPL1TATA box-binding protein-like protein 1. (186 aa)
TCEANCTranscription elongation factor A N-terminal and central domain containing. (350 aa)
TAF9BTATA-box binding protein associated factor 9b. (290 aa)
PRF1Perforin 1. (555 aa)
TAF13Transcription initiation factor TFIID subunit 13. (124 aa)
CCNT1Cyclin T1; Belongs to the cyclin family. (728 aa)
TAF12TFIID_20kDa domain-containing protein. (214 aa)
CDC73Parafibromin. (531 aa)
SSRP1FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...] (721 aa)
SPAG16Sperm associated antigen 16. (631 aa)
GTF2E2Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase. (320 aa)
EAF2EAF domain-containing protein. (261 aa)
GTF2E1General transcription factor IIE subunit 1. (450 aa)
POLR2DDNA-directed RNA polymerase II subunit RPB4. (142 aa)
LEO1RNA polymerase-associated protein LEO1. (666 aa)
SUPT6HTranscription elongation factor spt6; Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII). Belongs to the SPT6 family. (1726 aa)
NELFBNegative elongation factor complex member B. (580 aa)
PAF1PAF1 homolog, Paf1/RNA polymerase II complex component. (531 aa)
TAF1Transcription initiation factor TFIID subunit. (1895 aa)
MLLT1MLLT1 super elongation complex subunit. (557 aa)
TAF10Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. (218 aa)
NCBP2Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] (204 aa)
TAF4TATA-box binding protein associated factor 4. (1083 aa)
CTDP1CTD phosphatase subunit 1. (1238 aa)
CTR9CTR9 homolog, Paf1/RNA polymerase II complex component. (1173 aa)
CCNQCyclin-related protein FAM58A isoform 2; Belongs to the cyclin family. (228 aa)
TAF5TATA-box binding protein associated factor 5. (800 aa)
POLR2JDNA-directed RNA polymerase II subunit RPB11-a. (117 aa)
GTF2F2General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. (249 aa)
POLR2BDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1174 aa)
AFF1AF4/FMR2 family member 1. (1221 aa)
POLR2GS1 domain-containing protein. (209 aa)
TAF2TATA-box binding protein associated factor 2. (1251 aa)
SUPT16HSPT16 homolog, facilitates chromatin remodeling subunit. (1047 aa)
RTF1RTF1 homolog, Paf1/RNA polymerase II complex component. (711 aa)
AFF4AF4/FMR2 family member 4. (1162 aa)
LOC106994494TFIIS N-terminal domain-containing protein. (529 aa)
TAF4BTATA-box binding protein associated factor 4b. (862 aa)
GTF2A2Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family. (109 aa)
CDK7Cyclin-dependent kinase 7; Belongs to the protein kinase superfamily. (346 aa)
F6XRN0_MACMUUbiquitin-like domain-containing protein. (122 aa)
TCEA2Transcription elongation factor A2. (324 aa)
C14H11orf88Chromosome 14 C11orf88 homolog. (197 aa)
TAF7LTATA-box binding protein associated factor 7 like. (505 aa)
GTF2A1Transcription initiation factor IIA subunit 1 isoform 1. (376 aa)
SUPT5HTranscription elongation factor SPT5. (1087 aa)
NELFENegative elongation factor complex member E. (338 aa)
F7HPQ9_MACMUTAFII28 domain-containing protein. (199 aa)
F7HPQ7_MACMUTAFII28 domain-containing protein. (196 aa)
CCNT2Cyclin T2; Belongs to the cyclin family. (709 aa)
TAF3TATA-box binding protein associated factor 3. (1008 aa)
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
Server load: low (26%) [HD]