STRINGSTRING
BIVM BIVM POLR2I POLR2I MEIOB MEIOB RPA3 RPA3 POLE4 POLE4 POLR2D POLR2D RFC3 RFC3 RFC4 RFC4 RFC2 RFC2 POLE2 POLE2 USP7 USP7 USP40 USP40 HMGN1 HMGN1 ZNF830 ZNF830 CUL4B CUL4B RFC5 RFC5 NRDE2 NRDE2 ISY1 ISY1 POLR2J POLR2J XPA XPA RPS27A RPS27A POLR2B POLR2B POLR2G POLR2G PRPF19 PRPF19 POLE POLE RPS27A-2 RPS27A-2 ERCC4 ERCC4 UBA52 UBA52 PHF3 PHF3 ERCC6 ERCC6 CDK7 CDK7 PPIE PPIE TCEA2 TCEA2 CUL4A CUL4A POLD3 POLD3 F7DM39_MACMU F7DM39_MACMU ERCC8 ERCC8 POLK POLK F7GDN6_MACMU F7GDN6_MACMU TCEANC2 TCEANC2 SPOCD1 SPOCD1 RPA1 RPA1 KXD1 KXD1 POLR2H POLR2H MNAT1 MNAT1 POLR2E POLR2E TCEA3 TCEA3 UBC UBC ERCC2 ERCC2 POLE3 POLE3 CCNH CCNH TCEA1 TCEA1 ATAD5 ATAD5 UBB UBB ERCC1 ERCC1 RCBTB1 RCBTB1 GTF2H2 GTF2H2 RBX1 RBX1 RCBTB2 RCBTB2 POLR2F POLR2F RFC1 RFC1 GTF2H3 GTF2H3 POLR2A POLR2A HMGN1-2 HMGN1-2 PCNA PCNA GTF2H1 GTF2H1 GTF2H5 GTF2H5 ERCC3 ERCC3 ENSMMUP00000067421 ENSMMUP00000067421 POLD1 POLD1 XAB2 XAB2 TCEANC TCEANC ENSMMUP00000069269 ENSMMUP00000069269 DDB1 DDB1 UVSSA UVSSA ENSMMUP00000070235 ENSMMUP00000070235 POLR2C POLR2C AQR AQR ENSMMUP00000076576 ENSMMUP00000076576 EP300 EP300 ENSMMUP00000077297 ENSMMUP00000077297 UPK3BL2 UPK3BL2 POLD2 POLD2 GTF2H4 GTF2H4 POLD4 POLD4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
BIVMBIVM-ERCC5 readthrough. (1636 aa)
POLR2IDNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (125 aa)
MEIOBMeiosis specific with OB-fold. (550 aa)
RPA3Replication protein A 14 kDa subunit. (121 aa)
POLE4DNA polymerase epsilon subunit 4. (117 aa)
POLR2DDNA-directed RNA polymerase II subunit RPB4. (142 aa)
RFC3Replication factor C subunit 3 isoform 1. (356 aa)
RFC4Replication factor C subunit 4. (363 aa)
RFC2Replication factor C subunit 2. (233 aa)
POLE2DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (527 aa)
USP7Ubiquitin carboxyl-terminal hydrolase 7; Belongs to the peptidase C19 family. (1102 aa)
USP40Ubiquitin specific peptidase 40; Belongs to the peptidase C19 family. (1242 aa)
HMGN1Uncharacterized protein. (94 aa)
ZNF830Zinc finger protein 830. (372 aa)
CUL4BCullin 4B; Belongs to the cullin family. (933 aa)
RFC5Replication factor C subunit 5 isoform 1. (340 aa)
NRDE2Uncharacterized protein. (1164 aa)
ISY1Uncharacterized protein. (408 aa)
POLR2JDNA-directed RNA polymerase II subunit RPB11-a. (117 aa)
XPAXPA, DNA damage recognition and repair factor. (294 aa)
RPS27AUncharacterized protein. (156 aa)
POLR2BDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1174 aa)
POLR2GS1 domain-containing protein. (209 aa)
PRPF19Pre-mRNA processing factor 19. (512 aa)
POLEDNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2288 aa)
RPS27A-2Ubiquitin-40S ribosomal protein S27a. (156 aa)
ERCC4ERCC excision repair 4, endonuclease catalytic subunit. (916 aa)
UBA52Ubiquitin-60S ribosomal protein L40. (128 aa)
PHF3PHD finger protein 3. (2057 aa)
ERCC6ERCC excision repair 6, chromatin remodeling factor. (2061 aa)
CDK7Cyclin-dependent kinase 7; Belongs to the protein kinase superfamily. (346 aa)
PPIEPeptidylprolyl isomerase E. (369 aa)
TCEA2Transcription elongation factor A2. (324 aa)
CUL4ACullin 4A; Belongs to the cullin family. (759 aa)
POLD3DNA polymerase delta subunit 3. (466 aa)
F7DM39_MACMUUncharacterized protein. (143 aa)
ERCC8ERCC excision repair 8, CSA ubiquitin ligase complex subunit. (375 aa)
POLKDNA polymerase kappa. (868 aa)
F7GDN6_MACMUProtein kinase domain-containing protein. (165 aa)
TCEANC2Transcription elongation factor A N-terminal and central domain-containing protein 2. (208 aa)
SPOCD1SPOC domain containing 1. (1199 aa)
RPA1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (616 aa)
KXD1KxDL domain-containing protein. (231 aa)
POLR2HRNA polymerase II subunit H. (175 aa)
MNAT1CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (309 aa)
POLR2ERNA polymerase II subunit E. (160 aa)
TCEA3Transcription elongation factor A3. (348 aa)
UBCUncharacterized protein. (270 aa)
ERCC2TFIIH basal transcription factor complex helicase XPD subunit isoform 1. (760 aa)
POLE3DNA polymerase epsilon subunit 3. (147 aa)
CCNHCyclin H; Belongs to the cyclin family. (331 aa)
TCEA1Transcription elongation factor A protein 1 isoform 1. (301 aa)
ATAD5ATPase family AAA domain containing 5. (1848 aa)
UBBUncharacterized protein. (229 aa)
ERCC1ERCC excision repair 1, endonuclease non-catalytic subunit. (442 aa)
RCBTB1RCC1 and BTB domain-containing protein 1. (531 aa)
GTF2H2General transcription factor IIH subunit. (399 aa)
RBX1E3 ubiquitin-protein ligase RBX1. (108 aa)
RCBTB2RCC1 and BTB domain containing protein 2. (556 aa)
POLR2FUncharacterized protein. (179 aa)
RFC1Replication factor C subunit 1. (1146 aa)
GTF2H3General transcription factor IIH subunit 3. (308 aa)
POLR2ADNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1970 aa)
HMGN1-2Non-histone chromosomal protein HMG-14. (100 aa)
PCNAProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
GTF2H1General transcription factor IIH subunit 1. (548 aa)
GTF2H5General transcription factor IIH subunit 5. (71 aa)
ERCC3TFIIH basal transcription factor complex helicase XPB subunit. (782 aa)
ENSMMUP00000067421Ubiquitin-like domain-containing protein. (135 aa)
POLD1DNA polymerase. (1145 aa)
XAB2Pre-mRNA-splicing factor SYF1. (855 aa)
TCEANCTranscription elongation factor A N-terminal and central domain containing. (350 aa)
ENSMMUP00000069269Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (437 aa)
DDB1Damage specific DNA binding protein 1. (1147 aa)
UVSSAUV stimulated scaffold protein A. (769 aa)
ENSMMUP00000070235Ubiquitin-like domain-containing protein. (110 aa)
POLR2CRNA polymerase II subunit C. (306 aa)
AQRRNA helicase aquarius; Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre- mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing. (1492 aa)
ENSMMUP00000076576Uncharacterized protein. (100 aa)
EP300Histone acetyltransferase p300. (2414 aa)
ENSMMUP00000077297Uncharacterized protein. (168 aa)
UPK3BL2Uncharacterized protein. (266 aa)
POLD2DNA polymerase delta 2, accessory subunit. (536 aa)
GTF2H4General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (462 aa)
POLD4DNA polymerase delta subunit p12. (107 aa)
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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