STRINGSTRING
DYNLL2 DYNLL2 RANBP2 RANBP2 NUDC NUDC CENPQ CENPQ BIRC5 BIRC5 BUB1B BUB1B NSL1 NSL1 CENPT CENPT BUB1 BUB1 CLIP2 CLIP2 PPP2R1B PPP2R1B MTUS2 MTUS2 CKAP5 CKAP5 KNL1 KNL1 ITGB3BP ITGB3BP ENSMMUP00000053583 ENSMMUP00000053583 PPP2R5B PPP2R5B SKA2 SKA2 DYNC1LI1 DYNC1LI1 PPP2R5C PPP2R5C CENPO CENPO NUP98 NUP98 CENPM CENPM CMTM4 CMTM4 NUP85 NUP85 CLASP2 CLASP2 PPP2R5D PPP2R5D AHCTF1 AHCTF1 NUP133 NUP133 B9D2 B9D2 MAD1L1 MAD1L1 MIS12 MIS12 DSN1 DSN1 NDE1 NDE1 DYNC1H1 DYNC1H1 ANAPC1 ANAPC1 MAD2L1 MAD2L1 ENSMMUP00000070750 ENSMMUP00000070750 ANAPC15-2 ANAPC15-2 PPP2R5A PPP2R5A ANAPC7 ANAPC7 SPC25 SPC25 MAPRE1 MAPRE1 INCENP INCENP RCC2 RCC2 ERCC6L2 ERCC6L2 NDEL1 NDEL1 SPDL1 SPDL1 NUP37 NUP37 CDC26 CDC26 CENPI CENPI RANGAP1 RANGAP1 SGO2 SGO2 NUP160 NUP160 NUP43 NUP43 PPP2R5E PPP2R5E FAM89A FAM89A KNTC1 KNTC1 CLASP1 CLASP1 DYNC1I2 DYNC1I2 UBE2E1 UBE2E1 F6PNW7_MACMU F6PNW7_MACMU DYNC1I1 DYNC1I1 CENPP CENPP ANAPC10 ANAPC10 SPC24 SPC24 F7EBI3_MACMU F7EBI3_MACMU BUB3 BUB3 AURKB AURKB ANAPC2 ANAPC2 CDC20B CDC20B CENPC CENPC ZWILCH ZWILCH CDC23 CDC23 DYNLL1 DYNLL1 NUF2 NUF2 SKA1 SKA1 KIF2A KIF2A CENPU CENPU H9H3J4_MACMU H9H3J4_MACMU ANAPC11 ANAPC11 ERCC6L ERCC6L CENPN CENPN KIF18A KIF18A PPP1CC PPP1CC CDCA8 CDCA8 KIF2B KIF2B MEIOC MEIOC ANAPC16 ANAPC16 CENPF CENPF CENPA CENPA UBE2S UBE2S CENPK CENPK PLK1 PLK1 MAPRE2 MAPRE2 RPS27 RPS27 CDC27 CDC27 NDC80 NDC80 TAOK1 TAOK1 MAPRE3 MAPRE3 CISD1 CISD1 SEC13 SEC13 PPP2CB PPP2CB LOC714349 LOC714349 CLIP1 CLIP1 PPP2R1A PPP2R1A ZWINT ZWINT CENPL CENPL ZW10 ZW10 CENPH CENPH CENPE CENPE ANAPC4 ANAPC4 PAFAH1B1 PAFAH1B1 CDC16 CDC16 XPO1 XPO1 FAM89B FAM89B SGO1 SGO1 ANAPC5 ANAPC5 NUP107 NUP107 KIF2C KIF2C CDC20 CDC20 UBE2C UBE2C
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DYNLL2Dynein light chain. (89 aa)
RANBP2RAN binding protein 2. (3247 aa)
NUDCNuclear migration protein nudC. (332 aa)
CENPQCentromere protein Q. (268 aa)
BIRC5Baculoviral IAP repeat-containing protein 5 isoform 1. (142 aa)
BUB1BBUB1 mitotic checkpoint serine/threonine kinase B. (1063 aa)
NSL1NSL1 component of MIS12 kinetochore complex. (398 aa)
CENPTCentromere protein T. (560 aa)
BUB1BUB1 mitotic checkpoint serine/threonine kinase. (1085 aa)
CLIP2CAP-Gly domain-containing linker protein 2 isoform 1. (1046 aa)
PPP2R1BProtein phosphatase 2 scaffold subunit Abeta. (716 aa)
MTUS2Uncharacterized protein. (1383 aa)
CKAP5Cytoskeleton-associated protein 5 isoform a. (2032 aa)
KNL1Kinetochore scaffold 1. (2316 aa)
ITGB3BPIntegrin subunit beta 3 binding protein. (289 aa)
ENSMMUP00000053583HORMA domain-containing protein. (205 aa)
PPP2R5BSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (505 aa)
SKA2Spindle and kinetochore-associated protein 2 isoform 1. (121 aa)
DYNC1LI1Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. (523 aa)
PPP2R5CSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (579 aa)
CENPOCentromere protein O. (319 aa)
NUP98Nucleoporin 98. (1876 aa)
CENPMUncharacterized protein. (180 aa)
CMTM4Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. (628 aa)
NUP85Nuclear pore complex protein Nup85; Functions as a component of the nuclear pore complex (NPC). (656 aa)
CLASP2Uncharacterized protein. (1522 aa)
PPP2R5DSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (602 aa)
AHCTF1AT-hook containing transcription factor 1. (2336 aa)
NUP133Nucleoporin 133. (1157 aa)
B9D2B9 domain-containing protein 2. (175 aa)
MAD1L1Mitotic arrest deficient 1 like 1. (718 aa)
MIS12Protein MIS12 homolog. (205 aa)
DSN1Kinetochore-associated protein DSN1 homolog isoform 1. (354 aa)
NDE1NudE neurodevelopment protein 1. (346 aa)
DYNC1H1Dynein cytoplasmic 1 heavy chain 1. (4685 aa)
ANAPC1Anaphase promoting complex subunit 1. (2016 aa)
MAD2L1Mitotic spindle assembly checkpoint protein MAD2A. (205 aa)
ENSMMUP00000070750Uncharacterized protein. (105 aa)
ANAPC15-2Uncharacterized protein. (140 aa)
PPP2R5ASerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (486 aa)
ANAPC7Anaphase promoting complex subunit 7. (599 aa)
SPC25Kinetochore protein Spc25. (224 aa)
MAPRE1Microtubule-associated protein RP/EB family member 1. (268 aa)
INCENPInner centromere protein. (900 aa)
RCC2Regulator of chromosome condensation 2. (608 aa)
ERCC6L2Uncharacterized protein. (1551 aa)
NDEL1NudE neurodevelopment protein 1 like 1. (380 aa)
SPDL1Protein Spindly; Required for the localization of dynein and dynactin to the mitotic kintochore. Dynein is believed to control the initial lateral interaction between the kinetochore and spindle microtubules and to facilitate the subsequent formation of end-on kinetochore-microtubule attachments mediated by the NDC80 complex. Also required for correct spindle orientation. Does not appear to be required for the removal of spindle assembly checkpoint (SAC) proteins from the kinetochore upon bipolar spindle attachment. (622 aa)
NUP37WD_REPEATS_REGION domain-containing protein. (362 aa)
CDC26Anaphase-promoting complex subunit CDC26. (85 aa)
CENPICentromere protein I. (775 aa)
RANGAP1Ran GTPase activating protein 1. (709 aa)
SGO2Shugoshin 2. (1258 aa)
NUP160Nucleoporin 160. (1432 aa)
NUP43Nucleoporin 43. (380 aa)
PPP2R5ESerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (471 aa)
FAM89AFamily with sequence similarity 89 member A. (184 aa)
KNTC1Kinetochore associated 1. (2209 aa)
CLASP1Cytoplasmic linker associated protein 1. (1533 aa)
DYNC1I2WD_REPEATS_REGION domain-containing protein. (655 aa)
UBE2E1Ubiquitin conjugating enzyme E2 E1; Belongs to the ubiquitin-conjugating enzyme family. (447 aa)
F6PNW7_MACMUUncharacterized protein. (287 aa)
DYNC1I1WD_REPEATS_REGION domain-containing protein. (645 aa)
CENPPCentromere protein P. (288 aa)
ANAPC10Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. (185 aa)
SPC24SPC24 component of NDC80 kinetochore complex. (197 aa)
F7EBI3_MACMUUBIQUITIN_CONJUGAT_2 domain-containing protein. (189 aa)
BUB3WD_REPEATS_REGION domain-containing protein. (369 aa)
AURKBAurora kinase B; Belongs to the protein kinase superfamily. (345 aa)
ANAPC2Anaphase-promoting complex subunit 2; Belongs to the cullin family. (822 aa)
CDC20BCell division cycle 20B. (518 aa)
CENPCCentromere protein C. (950 aa)
ZWILCHZwilch kinetochore protein. (591 aa)
CDC23Cell division cycle protein 23 homolog. (597 aa)
DYNLL1Dynein light chain. (89 aa)
NUF2Kinetochore protein Nuf2. (464 aa)
SKA1Spindle and kinetochore associated complex subunit 1. (255 aa)
KIF2AKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (744 aa)
CENPUCentromere protein U. (419 aa)
H9H3J4_MACMUUncharacterized protein. (142 aa)
ANAPC11Uncharacterized protein. (192 aa)
ERCC6LERCC excision repair 6 like, spindle assembly checkpoint helicase. (1252 aa)
CENPNCentromere protein N isoform 2. (339 aa)
KIF18AKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (897 aa)
PPP1CCSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (337 aa)
CDCA8Cell division cycle associated 8. (280 aa)
KIF2BKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (670 aa)
MEIOCMeiosis specific with coiled-coil domain. (955 aa)
ANAPC16Anaphase-promoting complex subunit 16 isoform 1. (110 aa)
CENPFCentromere protein F. (3113 aa)
CENPACentromere protein A. (138 aa)
UBE2SUbiquitin-conjugating enzyme E2 S; Belongs to the ubiquitin-conjugating enzyme family. (222 aa)
CENPKCentromere protein K. (269 aa)
PLK1Serine/threonine-protein kinase PLK. (603 aa)
MAPRE2Microtubule-associated protein RP/EB family member 2 isoform 1. (327 aa)
RPS2740S ribosomal protein S27. (84 aa)
CDC27Cell division cycle protein 27 homolog isoform 1. (830 aa)
NDC80Kinetochore protein NDC80 homolog. (642 aa)
TAOK1TAO kinase 1. (1032 aa)
MAPRE3Microtubule associated protein RP/EB family member 3. (287 aa)
CISD1UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (210 aa)
SEC13SEC13 homolog, nuclear pore and COPII coat complex component; Belongs to the WD repeat SEC13 family. (368 aa)
PPP2CBSerine/threonine-protein phosphatase. (309 aa)
LOC714349Ubiquitin-conjugating enzyme E2 C isoform 1; Belongs to the ubiquitin-conjugating enzyme family. (179 aa)
CLIP1CAP-Gly domain containing linker protein 1. (2194 aa)
PPP2R1ASerine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform. (589 aa)
ZWINTZW10 interacting kinetochore protein. (277 aa)
CENPLUncharacterized protein. (390 aa)
ZW10Zw10 kinetochore protein. (778 aa)
CENPHCentromere protein H. (256 aa)
CENPECentromere protein E; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (2701 aa)
ANAPC4Anaphase promoting complex subunit 4. (981 aa)
PAFAH1B1Platelet-activating factor acetylhydrolase IB subunit alpha; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. Required during brain development for the proliferation of neuronal precursors and the migration of newly formed neurons from the ven [...] (411 aa)
CDC16Cell division cycle protein 16 homolog. (620 aa)
XPO1Exportin-1. (1071 aa)
FAM89BUncharacterized protein. (176 aa)
SGO1Shugoshin 1. (554 aa)
ANAPC5Anaphase-promoting complex subunit 5 isoform a. (755 aa)
NUP107Nuclear pore complex protein; Functions as a component of the nuclear pore complex (NPC). (925 aa)
KIF2CKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (725 aa)
CDC20Cell division cycle protein 20 homolog. (499 aa)
UBE2CUbiquitin conjugating enzyme E2 C. (179 aa)
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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