STRINGSTRING
GTF2H4 GTF2H4 CDK7 CDK7 POLR2G POLR2G POLR2B POLR2B GTF2F2 GTF2F2 POLR2J POLR2J POLR2I POLR2I POLR2D POLR2D NCBP2 NCBP2 RNMT RNMT NCBP2L NCBP2L C6orf15 C6orf15 POLR2C POLR2C RNGTT RNGTT ERCC3 ERCC3 GTF2H5 GTF2H5 GTF2H1 GTF2H1 POLR2A POLR2A GTF2H3 GTF2H3 POLR2F POLR2F GTF2H2 GTF2H2 NCBP1 NCBP1 CCNH CCNH ERCC2 ERCC2 POLR2E POLR2E MNAT1 MNAT1 POLR2H POLR2H UPK3BL2 UPK3BL2 F7GDN6_MACMU F7GDN6_MACMU SUPT5H SUPT5H DUSP11 DUSP11
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GTF2H4General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (462 aa)
CDK7Cyclin-dependent kinase 7; Belongs to the protein kinase superfamily. (346 aa)
POLR2GS1 domain-containing protein. (209 aa)
POLR2BDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1174 aa)
GTF2F2General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. (249 aa)
POLR2JDNA-directed RNA polymerase II subunit RPB11-a. (117 aa)
POLR2IDNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (125 aa)
POLR2DDNA-directed RNA polymerase II subunit RPB4. (142 aa)
NCBP2Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] (204 aa)
RNMTmRNA cap guanine-N7 methyltransferase. (476 aa)
NCBP2LNuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] (153 aa)
C6orf15Uncharacterized protein C6orf15 homolog. (314 aa)
POLR2CRNA polymerase II subunit C. (306 aa)
RNGTTPolynucleotide 5'-triphosphatase; Bifunctional mRNA-capping enzyme exhibiting RNA 5'- triphosphatase activity in the N-terminal part and mRNA guanylyltransferase activity in the C-terminal part. Catalyzes the first two steps of cap formation: by removing the gamma-phosphate from the 5'-triphosphate end of nascent mRNA to yield a diphosphate end, and by transferring the gmp moiety of GTP to the 5'-diphosphate terminus. (597 aa)
ERCC3TFIIH basal transcription factor complex helicase XPB subunit. (782 aa)
GTF2H5General transcription factor IIH subunit 5. (71 aa)
GTF2H1General transcription factor IIH subunit 1. (548 aa)
POLR2ADNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1970 aa)
GTF2H3General transcription factor IIH subunit 3. (308 aa)
POLR2FUncharacterized protein. (179 aa)
GTF2H2General transcription factor IIH subunit. (399 aa)
NCBP1Nuclear cap-binding protein subunit 1. (790 aa)
CCNHCyclin H; Belongs to the cyclin family. (331 aa)
ERCC2TFIIH basal transcription factor complex helicase XPD subunit isoform 1. (760 aa)
POLR2ERNA polymerase II subunit E. (160 aa)
MNAT1CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (309 aa)
POLR2HRNA polymerase II subunit H. (175 aa)
UPK3BL2Uncharacterized protein. (266 aa)
F7GDN6_MACMUProtein kinase domain-containing protein. (165 aa)
SUPT5HTranscription elongation factor SPT5. (1087 aa)
DUSP11Dual specificity phosphatase 11. (378 aa)
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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