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THOC7 THOC7 SRSF7 SRSF7 ZNF473 ZNF473 ZC3H11A ZC3H11A SNRPB SNRPB EIF4A3 EIF4A3 NCBP2 NCBP2 MAGOHB MAGOHB U2AF2 U2AF2 SRSF1 SRSF1 THOC1 THOC1 THOC2 THOC2 CPSF4L CPSF4L SNRPD3 SNRPD3 CSTF2T CSTF2T CPSF2 CPSF2 LSM11 LSM11 RBM8A RBM8A DHX38 DHX38 CLP1 CLP1 NCBP2L NCBP2L LOC114675497 LOC114675497 SRSF3 SRSF3 RNPS1 RNPS1 ENSMMUP00000071111 ENSMMUP00000071111 SNRPG SNRPG ENSMMUP00000069555 ENSMMUP00000069555 ENSMMUP00000067597 ENSMMUP00000067597 SNRPE SNRPE PCF11 PCF11 TPRG1L TPRG1L WDR33 WDR33 CSTF1 CSTF1 SLBP SLBP LUZP4 LUZP4 FYTTD1 FYTTD1 CDC40 CDC40 DDX39A DDX39A SRSF4 SRSF4 THOC5 THOC5 ENSMMUP00000056838 ENSMMUP00000056838 NUDT21 NUDT21 NCBP1 NCBP1 CPSF6 CPSF6 PAPOLA PAPOLA CSTF2 CSTF2 ENSMMUP00000051857 ENSMMUP00000051857 CSTF3 CSTF3 DDX39B DDX39B CPSF3 CPSF3 CASC3 CASC3 THOC3 THOC3 ENSMMUP00000047271 ENSMMUP00000047271 ALYREF ALYREF ENSMMUP00000041819 ENSMMUP00000041819 POLDIP3 POLDIP3 SRRM1 SRRM1 SRSF11 SRSF11 CHTOP CHTOP F6W8R8_MACMU F6W8R8_MACMU SRSF6 SRSF6 U2AF1 U2AF1 THOC6 THOC6 WDR25 WDR25 SLU7 SLU7 U2AF1L4 U2AF1L4 SRSF2 SRSF2 SRSF5 SRSF5 UPF3B UPF3B CPSF4 CPSF4 LSM10 LSM10 CPB2 CPB2 SRSF9 SRSF9 C11H12orf50 C11H12orf50 SYMPK SYMPK CPSF7 CPSF7 LOC713572 LOC713572 SREK1 SREK1 ZNF318 ZNF318
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
THOC7THO complex subunit 7 homolog. (204 aa)
SRSF7Serine and arginine rich splicing factor 7. (329 aa)
ZNF473Uncharacterized protein. (871 aa)
ZC3H11AZinc finger CCCH domain-containing protein 11A. (810 aa)
SNRPBSmall nuclear ribonucleoprotein-associated protein. (240 aa)
EIF4A3Eukaryotic initiation factor 4A-III; Belongs to the DEAD box helicase family. (411 aa)
NCBP2Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] (204 aa)
MAGOHBProtein mago nashi homolog 2. (148 aa)
U2AF2U2 snRNP auxiliary factor large subunit; Necessary for the splicing of pre-mRNA. Belongs to the splicing factor SR family. (471 aa)
SRSF1Uncharacterized protein. (287 aa)
THOC1THO complex subunit 1. (657 aa)
THOC2THO complex subunit 2. (1593 aa)
CPSF4LCleavage and polyadenylation specific factor 4 like. (179 aa)
SNRPD3Small nuclear ribonucleoprotein D3 polypeptide. (259 aa)
CSTF2TCleavage stimulation factor subunit 2 tau variant. (620 aa)
CPSF2Cleavage and polyadenylation specificity factor subunit 2. (782 aa)
LSM11LSM11, U7 small nuclear RNA associated. (358 aa)
RBM8ARNA-binding protein 8A; Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs. (174 aa)
DHX38Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16. (1227 aa)
CLP1Polyribonucleotide 5'-hydroxyl-kinase Clp1; Polynucleotide kinase that can phosphorylate the 5'-hydroxyl groups of double-stranded RNA (dsRNA), single-stranded RNA (ssRNA), double stranded DNA (dsDNA) and double-stranded DNA:RNA hybrids. dsRNA is phosphorylated more efficiently than dsDNA, and the RNA component of a DNA:RNA hybrid is phosphorylated more efficiently than the DNA component. Appears to have roles in both tRNA splicing and mRNA 3'-end formation. Component of the tRNA splicing endonuclease complex. Phosphorylates the 5'-terminus of the tRNA 3'-exon during tRNA splicing; thi [...] (425 aa)
NCBP2LNuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] (153 aa)
LOC114675497Uncharacterized protein. (409 aa)
SRSF3RRM domain-containing protein. (128 aa)
RNPS1RNA-binding protein with serine-rich domain 1. (305 aa)
ENSMMUP00000071111Uncharacterized protein. (176 aa)
SNRPGSmall nuclear ribonucleoprotein G; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. (79 aa)
ENSMMUP00000069555Uncharacterized protein. (71 aa)
ENSMMUP00000067597RRM domain-containing protein. (235 aa)
SNRPESmall nuclear ribonucleoprotein E; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. May indirectly play a role in hair development. (145 aa)
PCF11PCF11 cleavage and polyadenylation factor subunit. (1606 aa)
TPRG1LTumor protein p63-regulated gene 1-like protein. (272 aa)
WDR33WD repeat domain 33. (1387 aa)
CSTF1Cleavage stimulation factor subunit 1. (431 aa)
SLBPStem-loop binding protein. (349 aa)
LUZP4Uncharacterized protein. (304 aa)
FYTTD1UAP56-interacting factor isoform 1. (318 aa)
CDC40Pre-mRNA-processing factor 17. (579 aa)
DDX39ADExD-box helicase 39A. (448 aa)
SRSF4Serine/arginine-rich splicing factor 4. (497 aa)
THOC5THO complex 5. (694 aa)
ENSMMUP00000056838Small nuclear ribonucleoprotein E; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. May indirectly play a role in hair development. (53 aa)
NUDT21Cleavage and polyadenylation specificity factor subunit 5; Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The [...] (227 aa)
NCBP1Nuclear cap-binding protein subunit 1. (790 aa)
CPSF6Cleavage and polyadenylation specific factor 6. (588 aa)
PAPOLAPoly(A) polymerase; Polymerase that creates the 3'-poly(A) tail of mRNA's. (745 aa)
CSTF2Cleavage stimulation factor subunit 2. (626 aa)
ENSMMUP00000051857RRM domain-containing protein. (285 aa)
CSTF3Cleavage stimulation factor subunit 3 isoform 1. (717 aa)
DDX39BSpliceosome RNA helicase DDX39B; Involved in nuclear export of spliced and unspliced mRNA. Assembling component of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pat [...] (428 aa)
CPSF3Cleavage and polyadenylation specificity factor subunit 3. (684 aa)
CASC3Btz domain-containing protein. (706 aa)
THOC3THO complex subunit 3. (351 aa)
ENSMMUP00000047271RRM domain-containing protein. (300 aa)
ALYREFRRM domain-containing protein. (290 aa)
ENSMMUP00000041819Uncharacterized protein. (298 aa)
POLDIP3DNA polymerase delta interacting protein 3. (421 aa)
SRRM1Serine and arginine repetitive matrix 1. (906 aa)
SRSF11Serine and arginine rich splicing factor 11. (483 aa)
CHTOPChromatin target of PRMT1. (277 aa)
F6W8R8_MACMUSAP domain-containing protein. (213 aa)
SRSF6Serine and arginine rich splicing factor 6. (343 aa)
U2AF1Uncharacterized protein. (240 aa)
THOC6WD_REPEATS_REGION domain-containing protein. (422 aa)
WDR25WD repeat domain 25. (536 aa)
SLU7Pre-mRNA-splicing factor SLU7. (586 aa)
U2AF1L4Uncharacterized protein. (216 aa)
SRSF2Serine/arginine-rich splicing factor 2. (221 aa)
SRSF5Serine and arginine rich splicing factor 5. (272 aa)
UPF3BUncharacterized protein. (483 aa)
CPSF4Cleavage and polyadenylation specific factor 4. (224 aa)
LSM10U7 snRNA-associated Sm-like protein LSm10. (123 aa)
CPB2Zinc finger CCCH-type containing 13. (1697 aa)
SRSF9Serine/arginine-rich splicing factor 9. (221 aa)
C11H12orf50Chromosome 11 C12orf50 homolog. (414 aa)
SYMPKSymplekin. (1274 aa)
CPSF7Cleavage and polyadenylation specific factor 7. (471 aa)
LOC713572Uncharacterized protein. (333 aa)
SREK1Splicing regulatory glutamic acid and lysine rich protein 1. (592 aa)
ZNF318Zinc finger protein 318. (2279 aa)
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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