28 items (Macaca mulatta) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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Predicted Interactions

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Your Input:
	ERCC3	TFIIH basal transcription factor complex helicase XPB subunit. (782 aa)
	GTF2H5	General transcription factor IIH subunit 5. (71 aa)
	GTF2H1	General transcription factor IIH subunit 1. (548 aa)
	POLR2A	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1970 aa)
	GTF2H3	General transcription factor IIH subunit 3. (308 aa)
	POLR2F	Uncharacterized protein. (179 aa)
	GTF2H2	General transcription factor IIH subunit. (399 aa)
	CCNH	Cyclin H; Belongs to the cyclin family. (331 aa)
	ERCC2	TFIIH basal transcription factor complex helicase XPD subunit isoform 1. (760 aa)
	POLR2E	RNA polymerase II subunit E. (160 aa)
	MNAT1	CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (309 aa)
	GTF2H4	General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (462 aa)
	UPK3BL2	Uncharacterized protein. (266 aa)
	C6orf15	Uncharacterized protein C6orf15 homolog. (314 aa)
	POLR2C	RNA polymerase II subunit C. (306 aa)
	RNGTT	Polynucleotide 5'-triphosphatase; Bifunctional mRNA-capping enzyme exhibiting RNA 5'- triphosphatase activity in the N-terminal part and mRNA guanylyltransferase activity in the C-terminal part. Catalyzes the first two steps of cap formation: by removing the gamma-phosphate from the 5'-triphosphate end of nascent mRNA to yield a diphosphate end, and by transferring the gmp moiety of GTP to the 5'-diphosphate terminus. (597 aa)
	POLR2I	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (125 aa)
	POLR2D	DNA-directed RNA polymerase II subunit RPB4. (142 aa)
	RNMT	mRNA cap guanine-N7 methyltransferase. (476 aa)
	POLR2J	DNA-directed RNA polymerase II subunit RPB11-a. (117 aa)
	GTF2F2	General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. (249 aa)
	POLR2B	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1174 aa)
	POLR2G	S1 domain-containing protein. (209 aa)
	CDK7	Cyclin-dependent kinase 7; Belongs to the protein kinase superfamily. (346 aa)
	DUSP11	Dual specificity phosphatase 11. (378 aa)
	SUPT5H	Transcription elongation factor SPT5. (1087 aa)
	F7GDN6_MACMU	Protein kinase domain-containing protein. (165 aa)
	POLR2H	RNA polymerase II subunit H. (175 aa)

Your Current Organism:

Macaca mulatta

NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C6orf15	CCNH	ENSMMUP00000075556	ENSMMUP00000049916	Uncharacterized protein C6orf15 homolog.	Cyclin H; Belongs to the cyclin family.	0.739
C6orf15	CDK7	ENSMMUP00000075556	ENSMMUP00000024498	Uncharacterized protein C6orf15 homolog.	Cyclin-dependent kinase 7; Belongs to the protein kinase superfamily.	0.606
C6orf15	DUSP11	ENSMMUP00000075556	ENSMMUP00000028362	Uncharacterized protein C6orf15 homolog.	Dual specificity phosphatase 11.	0.786
C6orf15	ERCC3	ENSMMUP00000075556	ENSMMUP00000065807	Uncharacterized protein C6orf15 homolog.	TFIIH basal transcription factor complex helicase XPB subunit.	0.597
C6orf15	F7GDN6_MACMU	ENSMMUP00000075556	ENSMMUP00000038323	Uncharacterized protein C6orf15 homolog.	Protein kinase domain-containing protein.	0.604
C6orf15	GTF2F2	ENSMMUP00000075556	ENSMMUP00000016596	Uncharacterized protein C6orf15 homolog.	General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity.	0.860
C6orf15	GTF2H1	ENSMMUP00000075556	ENSMMUP00000063114	Uncharacterized protein C6orf15 homolog.	General transcription factor IIH subunit 1.	0.749
C6orf15	GTF2H3	ENSMMUP00000075556	ENSMMUP00000058454	Uncharacterized protein C6orf15 homolog.	General transcription factor IIH subunit 3.	0.653
C6orf15	GTF2H4	ENSMMUP00000075556	ENSMMUP00000080485	Uncharacterized protein C6orf15 homolog.	General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family.	0.702
C6orf15	MNAT1	ENSMMUP00000075556	ENSMMUP00000043818	Uncharacterized protein C6orf15 homolog.	CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex.	0.653
C6orf15	POLR2A	ENSMMUP00000075556	ENSMMUP00000060307	Uncharacterized protein C6orf15 homolog.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.676
C6orf15	POLR2B	ENSMMUP00000075556	ENSMMUP00000018410	Uncharacterized protein C6orf15 homolog.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.960
C6orf15	POLR2C	ENSMMUP00000075556	ENSMMUP00000074354	Uncharacterized protein C6orf15 homolog.	RNA polymerase II subunit C.	0.955
C6orf15	POLR2D	ENSMMUP00000075556	ENSMMUP00000002660	Uncharacterized protein C6orf15 homolog.	DNA-directed RNA polymerase II subunit RPB4.	0.954
C6orf15	POLR2E	ENSMMUP00000075556	ENSMMUP00000045349	Uncharacterized protein C6orf15 homolog.	RNA polymerase II subunit E.	0.955
C6orf15	POLR2F	ENSMMUP00000075556	ENSMMUP00000057144	Uncharacterized protein C6orf15 homolog.	Uncharacterized protein.	0.940
C6orf15	POLR2G	ENSMMUP00000075556	ENSMMUP00000018873	Uncharacterized protein C6orf15 homolog.	S1 domain-containing protein.	0.953
C6orf15	POLR2H	ENSMMUP00000075556	ENSMMUP00000043667	Uncharacterized protein C6orf15 homolog.	RNA polymerase II subunit H.	0.937
C6orf15	POLR2I	ENSMMUP00000075556	ENSMMUP00000000706	Uncharacterized protein C6orf15 homolog.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.	0.939
C6orf15	POLR2J	ENSMMUP00000075556	ENSMMUP00000015766	Uncharacterized protein C6orf15 homolog.	DNA-directed RNA polymerase II subunit RPB11-a.	0.819