STRINGSTRING
LOC695427-2 LOC695427-2 H2BU1 H2BU1 H2AC20 H2AC20 KMT2B KMT2B HIST1H2BJ HIST1H2BJ GP1BA GP1BA PRMT1 PRMT1 AGO4 AGO4 KMT2A KMT2A THBS1 THBS1 TMEM62 TMEM62 KMT2C KMT2C SIN3A SIN3A H2AFB3 H2AFB3 HDAC1 HDAC1 NR4A3 NR4A3 TNRC6C TNRC6C SETD1B SETD1B ITGA2B ITGA2B ASH2L ASH2L WDR5 WDR5 PRMT8 PRMT8 DPY30 DPY30 LOC698767 LOC698767 KMT2D KMT2D WDR5B WDR5B LOC699443 LOC699443 MYL9 MYL9 GATA1 GATA1 H2AFJ H2AFJ TNRC6A TNRC6A PRKCQ PRKCQ HIST1H2BA HIST1H2BA KMT2E KMT2E SIN3B SIN3B LOC714001 LOC714001 F7C6W4_MACMU F7C6W4_MACMU HIST1H2AJ HIST1H2AJ F6PS34_MACMU F6PS34_MACMU NFE2 NFE2 SETD5 SETD5 LOC699317 LOC699317 H2AFX H2AFX RBBP5 RBBP5 H2AFZ H2AFZ LOC106996511 LOC106996511 HIST1H2AC HIST1H2AC AGO3 AGO3 LOC710748 LOC710748 HIST1H2BM HIST1H2BM H2BC5 H2BC5 LOC114669830 LOC114669830 AGO1 AGO1 ENSMMUP00000057513 ENSMMUP00000057513 H2BE1 H2BE1 HIST1H2BH HIST1H2BH LOC696506 LOC696506 LOC106995531 LOC106995531 LOC704104 LOC704104 KAT2B KAT2B HIST1H3D HIST1H3D LOC106996511-2 LOC106996511-2 H3C8 H3C8 LOC696808 LOC696808 LOC106996511-3 LOC106996511-3 LOC697115 LOC697115 LOC106996511-4 LOC106996511-4 LOC696808-2 LOC696808-2 LOC696808-3 LOC696808-3 SETD1A SETD1A ENSMMUP00000066392 ENSMMUP00000066392 LOC698105 LOC698105 ENSMMUP00000067674 ENSMMUP00000067674 LOC693939 LOC693939 ENSMMUP00000068277 ENSMMUP00000068277 LOC106996511-5 LOC106996511-5 LOC718280 LOC718280 MOV10 MOV10 LOC698354 LOC698354 LOC106996511-6 LOC106996511-6 CBFB CBFB LOC704341 LOC704341 LOC703889 LOC703889 ZFPM1 ZFPM1 LOC693887 LOC693887 LOC708899 LOC708899 LOC695323 LOC695323 LOC699110 LOC699110 PF4 PF4 RUNX1 RUNX1 LOC100430668 LOC100430668 EP300 EP300 LOC697721 LOC697721 ENSMMUP00000077143 ENSMMUP00000077143 ENSMMUP00000077416 ENSMMUP00000077416 HIST1H2BO HIST1H2BO PRMT6 PRMT6 HIST1H2BK HIST1H2BK H2AFV H2AFV LOC695427 LOC695427 H2BC15 H2BC15
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC695427-2Histone H3; Belongs to the histone H3 family. (136 aa)
H2BU1Histone H2B; Belongs to the histone H2B family. (126 aa)
H2AC20Histone H2A; Belongs to the histone H2A family. (129 aa)
KMT2BHistone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. TRX/MLL subfamily. (2716 aa)
HIST1H2BJHistone H2B; Belongs to the histone H2B family. (126 aa)
GP1BAGlycoprotein Ib platelet subunit alpha. (754 aa)
PRMT1Methyltransf_25 domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (371 aa)
AGO4Protein argonaute-4; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. (979 aa)
KMT2AHistone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. TRX/MLL subfamily. (4001 aa)
THBS1Thrombospondin 1. (1170 aa)
TMEM62Transmembrane protein 62. (643 aa)
KMT2CLysine methyltransferase 2C. (5027 aa)
SIN3ASIN3 transcription regulator family member A. (1273 aa)
H2AFB3Histone H2A; Belongs to the histone H2A family. (115 aa)
HDAC1Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (482 aa)
NR4A3Nuclear receptor subfamily 4 group A member 3. (717 aa)
TNRC6CUBA domain-containing protein. (1928 aa)
SETD1BSET domain containing 1B, histone lysine methyltransferase. (1796 aa)
ITGA2BIntegrin subunit alpha 2b; Belongs to the integrin alpha chain family. (1090 aa)
ASH2LASH2 like, histone lysine methyltransferase complex subunit. (635 aa)
WDR5WD repeat domain 5. (426 aa)
PRMT8Protein arginine N-methyltransferase 8; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (394 aa)
DPY30Dpy-30 histone methyltransferase complex regulatory subunit. (99 aa)
LOC698767Histone domain-containing protein; Belongs to the histone H2B family. (175 aa)
KMT2DLysine methyltransferase 2D. (5578 aa)
WDR5BUncharacterized protein. (330 aa)
LOC699443Histone H3; Belongs to the histone H3 family. (136 aa)
MYL9Myosin regulatory light polypeptide 9 isoform a. (172 aa)
GATA1GATA binding protein 1. (413 aa)
H2AFJHistone H2A; Belongs to the histone H2A family. (129 aa)
TNRC6ATrinucleotide repeat containing adaptor 6A. (1968 aa)
PRKCQProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (739 aa)
HIST1H2BAHistone H2B; Belongs to the histone H2B family. (127 aa)
KMT2EHistone-lysine N-methyltransferase MLL5. (1859 aa)
SIN3BSIN3 transcription regulator family member B. (1159 aa)
LOC714001Histone H2B; Belongs to the histone H2B family. (126 aa)
F7C6W4_MACMUHistone H2A; Belongs to the histone H2A family. (166 aa)
HIST1H2AJHistone H2A; Belongs to the histone H2A family. (128 aa)
F6PS34_MACMUHistone H2A; Belongs to the histone H2A family. (169 aa)
NFE2Nuclear factor, erythroid-derived 2 45 kDa subunit. (373 aa)
SETD5SET domain-containing protein. (1481 aa)
LOC699317Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
H2AFXHistone H2A; Belongs to the histone H2A family. (143 aa)
RBBP5RB binding protein 5, histone lysine methyltransferase complex subunit. (539 aa)
H2AFZHistone H2A; Belongs to the histone H2A family. (128 aa)
LOC106996511Histone H4. (103 aa)
HIST1H2ACHistone H2A; Belongs to the histone H2A family. (130 aa)
AGO3Protein argonaute-3; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. (860 aa)
LOC710748Histone H3; Belongs to the histone H3 family. (136 aa)
HIST1H2BMHistone H2B; Belongs to the histone H2B family. (126 aa)
H2BC5Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC114669830Histone H3; Belongs to the histone H3 family. (136 aa)
AGO1Protein argonaute-1; Belongs to the argonaute family. (857 aa)
ENSMMUP00000057513Uncharacterized protein. (260 aa)
H2BE1Histone H2B; Belongs to the histone H2B family. (122 aa)
HIST1H2BHHistone H2B; Belongs to the histone H2B family. (126 aa)
LOC696506Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC106995531Histone H2A-Bbd type 2/3-like. (115 aa)
LOC704104Histone domain-containing protein. (154 aa)
KAT2BLysine acetyltransferase 2B. (866 aa)
HIST1H3DHistone cluster 1, H3d. (136 aa)
LOC106996511-2Histone H4. (103 aa)
H3C8H3 clustered histone 8. (136 aa)
LOC696808Histone H2B type 1. (126 aa)
LOC106996511-3Histone H4. (103 aa)
LOC697115Histone H4. (103 aa)
LOC106996511-4Histone H4. (103 aa)
LOC696808-2Histone H2B type 1. (126 aa)
LOC696808-3Histone H2B type 1. (126 aa)
SETD1AUncharacterized protein. (1756 aa)
ENSMMUP00000066392annotation not available (136 aa)
LOC698105Histone H3.1. (136 aa)
ENSMMUP00000067674Uncharacterized protein. (87 aa)
LOC693939Histone H3; Belongs to the histone H3 family. (136 aa)
ENSMMUP00000068277Histone H3; Belongs to the histone H3 family. (136 aa)
LOC106996511-5Histone H4. (103 aa)
LOC718280Histone domain-containing protein. (136 aa)
MOV10Putative helicase MOV-10. (1003 aa)
LOC698354Histone H4. (103 aa)
LOC106996511-6Histone H4. (103 aa)
CBFBCore-binding factor subunit beta isoform 1. (187 aa)
LOC704341Histone H4. (103 aa)
LOC703889Histone H3.1. (136 aa)
ZFPM1Zinc finger protein, FOG family member 1. (1024 aa)
LOC693887Histone H3.3. (136 aa)
LOC708899Histone H3.3. (136 aa)
LOC695323Histone H4. (103 aa)
LOC699110Histone H4. (103 aa)
PF4C-X-C motif chemokine. (101 aa)
RUNX1Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (480 aa)
LOC100430668Histone H3.1. (136 aa)
EP300Histone acetyltransferase p300. (2414 aa)
LOC697721Histone H4. (103 aa)
ENSMMUP00000077143Uncharacterized protein. (434 aa)
ENSMMUP00000077416Uncharacterized protein. (113 aa)
HIST1H2BOHistone H2B; Belongs to the histone H2B family. (126 aa)
PRMT6Protein arginine N-methyltransferase 6; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (375 aa)
HIST1H2BKHistone H2B; Belongs to the histone H2B family. (126 aa)
H2AFVHistone H2A; Belongs to the histone H2A family. (138 aa)
LOC695427Histone H3.1. (136 aa)
H2BC15Histone H2B; Belongs to the histone H2B family. (126 aa)
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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