STRINGSTRING
MNAT1 MNAT1 H2AFX H2AFX PSMA8 PSMA8 PSMD10 PSMD10 LOC699317 LOC699317 PSMD6 PSMD6 GATA2 GATA2 F7GDN6_MACMU F7GDN6_MACMU F7HHF9_MACMU F7HHF9_MACMU F6PS34_MACMU F6PS34_MACMU F7C6W4_MACMU F7C6W4_MACMU LOC714001 LOC714001 F7ALC4_MACMU F7ALC4_MACMU PSMC1 PSMC1 HIST1H2BA HIST1H2BA PSMB4 PSMB4 PSMD3 PSMD3 PSMB1 PSMB1 LMO3 LMO3 CDK7 CDK7 PSMA7 PSMA7 H2AFJ H2AFJ PSMC4 PSMC4 TP73 TP73 GATA1 GATA1 PSMD9 PSMD9 LOC699443 LOC699443 UBA52 UBA52 PSMC3 PSMC3 SPI1 SPI1 RPS27A-2 RPS27A-2 RPS27A RPS27A PSMB2 PSMB2 PSMB6 PSMB6 ITCH ITCH PSME1 PSME1 PSMD1 PSMD1 PSMD13 PSMD13 PSMB9 PSMB9 PSMA4 PSMA4 H2AFB3 H2AFB3 LDB1 LDB1 PSME4 PSME4 PSMD4 PSMD4 LMO2 LMO2 GATA3 GATA3 PSMB11 PSMB11 PSMB5 PSMB5 KMT2A KMT2A PSMF1 PSMF1 TCF12 TCF12 PSMC2 PSMC2 YAP1 YAP1 HIST1H2BJ HIST1H2BJ PSMD5 PSMD5 PSMD12 PSMD12 H2AC20 H2AC20 H2BU1 H2BU1 LOC695427-2 LOC695427-2 PSMD2 PSMD2 ABL1 ABL1 H2BC5 H2BC5 LOC114669830 LOC114669830 PSMD8 PSMD8 H2BE1 H2BE1 LOC696506 LOC696506 LOC106995531 LOC106995531 PSMA3 PSMA3 LOC704104 LOC704104 HIST1H3D HIST1H3D LOC106996511-2 LOC106996511-2 LMO1 LMO1 PSMC5 PSMC5 TCF3 TCF3 PSMC6 PSMC6 H3C8 H3C8 LOC696808 LOC696808 LOC106996511-3 LOC106996511-3 PSMD7 PSMD7 LOC697115 LOC697115 LOC106996511-4 LOC106996511-4 LOC696808-2 LOC696808-2 LOC696808-3 LOC696808-3 ENSMMUP00000066392 ENSMMUP00000066392 LOC698105 LOC698105 ENSMMUP00000067421 ENSMMUP00000067421 ENSMMUP00000067674 ENSMMUP00000067674 PSMB10 PSMB10 LOC693939 LOC693939 ENSMMUP00000068277 ENSMMUP00000068277 LOC106996511-5 LOC106996511-5 LOC718280 LOC718280 ENSMMUP00000069031 ENSMMUP00000069031 TAL1 TAL1 LOC698354 LOC698354 LOC106996511-6 LOC106996511-6 ENSMMUP00000070235 ENSMMUP00000070235 CBFB CBFB LOC704341 LOC704341 PSMA1 PSMA1 LDB2 LDB2 LOC703889 LOC703889 PSMB7 PSMB7 LOC699631 LOC699631 LOC693887 LOC693887 LOC708899 LOC708899 PSMD11 PSMD11 LOC695323 LOC695323 LOC699110 LOC699110 RUNX1 RUNX1 LOC100430668 LOC100430668 LOC697721 LOC697721 ENSMMUP00000077416 ENSMMUP00000077416 HIST1H2BO HIST1H2BO LOC719262 LOC719262 PSMA5 PSMA5 HIST1H2BK HIST1H2BK H2AFV H2AFV LOC695427 LOC695427 H2BC15 H2BC15 PSMA2 PSMA2 PSME3 PSME3 PSMD14 PSMD14 PSME2 PSME2 LOC710748 LOC710748 UBB UBB CCNH CCNH HIST1H2AC HIST1H2AC PSMA6 PSMA6 MYB MYB PSMB3 PSMB3 LOC106996511 LOC106996511 H2AFZ H2AFZ UBC UBC
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MNAT1CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (309 aa)
H2AFXHistone H2A; Belongs to the histone H2A family. (143 aa)
PSMA8Proteasome subunit alpha type. (250 aa)
PSMD10Proteasome 26S subunit, non-ATPase 10. (253 aa)
LOC699317Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
PSMD6Proteasome 26S subunit, non-ATPase 6. (442 aa)
GATA2GATA binding protein 2. (480 aa)
F7GDN6_MACMUProtein kinase domain-containing protein. (165 aa)
F7HHF9_MACMUAAA domain-containing protein; Belongs to the AAA ATPase family. (352 aa)
F6PS34_MACMUHistone H2A; Belongs to the histone H2A family. (169 aa)
F7C6W4_MACMUHistone H2A; Belongs to the histone H2A family. (166 aa)
LOC714001Histone H2B; Belongs to the histone H2B family. (126 aa)
F7ALC4_MACMUAAA domain-containing protein; Belongs to the AAA ATPase family. (360 aa)
PSMC126S protease regulatory subunit 4; Belongs to the AAA ATPase family. (440 aa)
HIST1H2BAHistone H2B; Belongs to the histone H2B family. (127 aa)
PSMB4Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa)
PSMD326S proteasome non-ATPase regulatory subunit 3. (534 aa)
PSMB1Proteasome subunit beta. (241 aa)
LMO3Uncharacterized protein. (187 aa)
CDK7Cyclin-dependent kinase 7; Belongs to the protein kinase superfamily. (346 aa)
PSMA7Proteasome subunit alpha type. (248 aa)
H2AFJHistone H2A; Belongs to the histone H2A family. (129 aa)
PSMC426S protease regulatory subunit 6B isoform 1; Belongs to the AAA ATPase family. (418 aa)
TP73Tumor protein p73; Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein. (660 aa)
GATA1GATA binding protein 1. (413 aa)
PSMD926S proteasome non-ATPase regulatory subunit 9. (223 aa)
LOC699443Histone H3; Belongs to the histone H3 family. (136 aa)
UBA52Ubiquitin-60S ribosomal protein L40. (128 aa)
PSMC326S protease regulatory subunit 6A; Belongs to the AAA ATPase family. (439 aa)
SPI1Spi-1 proto-oncogene. (271 aa)
RPS27A-2Ubiquitin-40S ribosomal protein S27a. (156 aa)
RPS27AUncharacterized protein. (156 aa)
PSMB2Proteasome subunit beta. (201 aa)
PSMB6Proteasome subunit beta. (285 aa)
ITCHE3 ubiquitin-protein ligase. (918 aa)
PSME1Proteasome activator complex subunit 1 isoform 1. (249 aa)
PSMD126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (953 aa)
PSMD13Proteasome 26S subunit, non-ATPase 13. (378 aa)
PSMB9Proteasome subunit beta. (219 aa)
PSMA4Proteasome subunit alpha type. (300 aa)
H2AFB3Histone H2A; Belongs to the histone H2A family. (115 aa)
LDB1LIM domain-binding protein 1 isoform 1. (411 aa)
PSME4Proteasome activator complex subunit 4. (1843 aa)
PSMD4VWFA domain-containing protein. (400 aa)
LMO2Uncharacterized protein. (222 aa)
GATA3GATA binding protein 3. (444 aa)
PSMB11Proteasome subunit beta. (243 aa)
PSMB5Proteasome subunit beta. (263 aa)
KMT2AHistone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. TRX/MLL subfamily. (4001 aa)
PSMF1Proteasome inhibitor subunit 1. (288 aa)
TCF12Transcription factor 12 isoform a. (706 aa)
PSMC226S protease regulatory subunit 7 isoform 1; Belongs to the AAA ATPase family. (433 aa)
YAP1Yes associated protein 1. (508 aa)
HIST1H2BJHistone H2B; Belongs to the histone H2B family. (126 aa)
PSMD526S proteasome non-ATPase regulatory subunit 5. (504 aa)
PSMD12Proteasome 26S subunit, non-ATPase 12. (476 aa)
H2AC20Histone H2A; Belongs to the histone H2A family. (129 aa)
H2BU1Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC695427-2Histone H3; Belongs to the histone H3 family. (136 aa)
PSMD226S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (908 aa)
ABL1Tyrosine-protein kinase. (1149 aa)
H2BC5Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC114669830Histone H3; Belongs to the histone H3 family. (136 aa)
PSMD8CSN8_PSD8_EIF3K domain-containing protein. (364 aa)
H2BE1Histone H2B; Belongs to the histone H2B family. (122 aa)
LOC696506Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC106995531Histone H2A-Bbd type 2/3-like. (115 aa)
PSMA3Proteasome subunit alpha type. (267 aa)
LOC704104Histone domain-containing protein. (154 aa)
HIST1H3DHistone cluster 1, H3d. (136 aa)
LOC106996511-2Histone H4. (103 aa)
LMO1LIM domain only 1. (156 aa)
PSMC526S protease regulatory subunit 8 isoform 1; Belongs to the AAA ATPase family. (406 aa)
TCF3Transcription factor 3. (654 aa)
PSMC6AAA domain-containing protein; Belongs to the AAA ATPase family. (410 aa)
H3C8H3 clustered histone 8. (136 aa)
LOC696808Histone H2B type 1. (126 aa)
LOC106996511-3Histone H4. (103 aa)
PSMD7MPN domain-containing protein. (323 aa)
LOC697115Histone H4. (103 aa)
LOC106996511-4Histone H4. (103 aa)
LOC696808-2Histone H2B type 1. (126 aa)
LOC696808-3Histone H2B type 1. (126 aa)
ENSMMUP00000066392annotation not available (136 aa)
LOC698105Histone H3.1. (136 aa)
ENSMMUP00000067421Ubiquitin-like domain-containing protein. (135 aa)
ENSMMUP00000067674Uncharacterized protein. (87 aa)
PSMB10Proteasome subunit beta. (312 aa)
LOC693939Histone H3; Belongs to the histone H3 family. (136 aa)
ENSMMUP00000068277Histone H3; Belongs to the histone H3 family. (136 aa)
LOC106996511-5Histone H4. (103 aa)
LOC718280Histone domain-containing protein. (136 aa)
ENSMMUP00000069031Uncharacterized protein. (158 aa)
TAL1BHLH domain-containing protein. (331 aa)
LOC698354Histone H4. (103 aa)
LOC106996511-6Histone H4. (103 aa)
ENSMMUP00000070235Ubiquitin-like domain-containing protein. (110 aa)
CBFBCore-binding factor subunit beta isoform 1. (187 aa)
LOC704341Histone H4. (103 aa)
PSMA1Proteasome endopeptidase complex. (301 aa)
LDB2LID domain-containing protein. (374 aa)
LOC703889Histone H3.1. (136 aa)
PSMB7Proteasome subunit beta. (277 aa)
LOC699631Proteasome subunit alpha type. (206 aa)
LOC693887Histone H3.3. (136 aa)
LOC708899Histone H3.3. (136 aa)
PSMD11Proteasome 26S subunit, non-ATPase 11. (454 aa)
LOC695323Histone H4. (103 aa)
LOC699110Histone H4. (103 aa)
RUNX1Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (480 aa)
LOC100430668Histone H3.1. (136 aa)
LOC697721Histone H4. (103 aa)
ENSMMUP00000077416Uncharacterized protein. (113 aa)
HIST1H2BOHistone H2B; Belongs to the histone H2B family. (126 aa)
LOC719262Transcription factor Spi-B. (262 aa)
PSMA5Proteasome subunit alpha type. (241 aa)
HIST1H2BKHistone H2B; Belongs to the histone H2B family. (126 aa)
H2AFVHistone H2A; Belongs to the histone H2A family. (138 aa)
LOC695427Histone H3.1. (136 aa)
H2BC15Histone H2B; Belongs to the histone H2B family. (126 aa)
PSMA2Proteasome subunit alpha type. (234 aa)
PSME3Proteasome activator subunit 3. (265 aa)
PSMD1426S proteasome non-ATPase regulatory subunit 14. (310 aa)
PSME2Proteasome activator subunit 2. (248 aa)
LOC710748Histone H3; Belongs to the histone H3 family. (136 aa)
UBBUncharacterized protein. (229 aa)
CCNHCyclin H; Belongs to the cyclin family. (331 aa)
HIST1H2ACHistone H2A; Belongs to the histone H2A family. (130 aa)
PSMA6Proteasome subunit alpha type. (246 aa)
MYBMYB proto-oncogene, transcription factor. (761 aa)
PSMB3Proteasome subunit beta. (261 aa)
LOC106996511Histone H4. (103 aa)
H2AFZHistone H2A; Belongs to the histone H2A family. (128 aa)
UBCUncharacterized protein. (270 aa)
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
Server load: low (18%) [HD]