64 items (Macaca mulatta) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	WWP2	E3 ubiquitin-protein ligase. (870 aa)
	CFTR	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...] (1489 aa)
	ARHGAP26	Rho GTPase activating protein 26. (814 aa)
	MPP3	Membrane palmitoylated protein 3; Belongs to the MAGUK family. (620 aa)
	CDC42BPA	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1845 aa)
	PLEKHG3	Pleckstrin homology and RhoGEF domain containing G3. (1361 aa)
	ARHGAP32	Rho GTPase activating protein 32. (2136 aa)
	ENSMMUP00000076986	PHB domain-containing protein. (220 aa)
	GFOD1	Glucose-fructose oxidoreductase domain-containing protein 1 isoform 1. (390 aa)
	OPHN1	Oligophrenin-1. (802 aa)
	CDC42BPB	CDC42 binding protein kinase beta; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1728 aa)
	PREX1	Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1. (1661 aa)
	SLC1A5	Amino acid transporter. (542 aa)
	MPP7	Membrane palmitoylated protein 7; Belongs to the MAGUK family. (576 aa)
	ANAPC15	Late endosomal/lysosomal adaptor, MAPK and MTOR activator 1. (253 aa)
	CDC42	Cell division control protein 42 homolog isoform 1. (191 aa)
	ITSN1	Intersectin 1. (1720 aa)
	FNBP1	Formin binding protein 1. (651 aa)
	SRGAP2	SLIT-ROBO Rho GTPase-activating protein 2 isoform a. (1071 aa)
	ARHGAP17	Rho GTPase activating protein 17. (930 aa)
	SCRIB	Scribble planar cell polarity protein. (1451 aa)
	ARHGAP35	Rho GTPase activating protein 35. (1499 aa)
	CPNE8	Copine 8. (516 aa)
	CPNE9	Copine family member 9. (553 aa)
	GIT1	GIT ArfGAP 1. (794 aa)
	DEPDC1B	DEP domain-containing protein 1B isoform 1. (529 aa)
	ARHGEF9	Cdc42 guanine nucleotide exchange factor 9. (545 aa)
	CDC42EP1	CDC42 effector protein 1. (398 aa)
	IQGAP3	IQ motif containing GTPase activating protein 3. (1631 aa)
	TFRC	Transferrin receptor protein 1. (760 aa)
	FMN1	Formin 1. (1425 aa)
	ARHGAP21	Uncharacterized protein. (1992 aa)
	SYDE1	Synapse defective Rho GTPase homolog 1. (733 aa)
	ANKRD33B	Ankyrin repeat domain 33B. (488 aa)
	CAV3	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (196 aa)
	RAB7A	RAB7A, member RAS oncogene family. (220 aa)
	ENSMMUP00000066266	Uncharacterized protein. (188 aa)
	FMN2	Formin 2. (1833 aa)
	CDC42EP3	Cdc42 effector protein 3. (254 aa)
	ARL13B	ADP ribosylation factor like GTPase 13B. (457 aa)
	ARHGAP5	Uncharacterized protein. (1501 aa)
	ARHGAP33	Rho GTPase activating protein 33. (1287 aa)
	SLC4A7	Anion exchange protein. (1242 aa)
	PAK1	Non-specific serine/threonine protein kinase. (575 aa)
	CDC42EP4	Cdc42 effector protein 4. (356 aa)
	DLC1	DLC1 Rho GTPase activating protein. (1528 aa)
	CAV1	Caveolin 1. (303 aa)
	SNAP23	Synaptosomal-associated protein; Belongs to the SNAP-25 family. (224 aa)
	DIAPH3	Diaphanous related formin 3. (1192 aa)
	ARHGEF7	Rho guanine nucleotide exchange factor 7. (862 aa)
	PAK4	Non-specific serine/threonine protein kinase. (597 aa)
	JUP	Uncharacterized protein. (744 aa)
	STOM	Erythrocyte band 7 integral membrane protein isoform a. (288 aa)
	PAK2	Non-specific serine/threonine protein kinase. (524 aa)
	IQGAP1	IQ motif containing GTPase activating protein 1. (1667 aa)
	WASL	Neural Wiskott-Aldrich syndrome protein. (505 aa)
	GIT2	GIT ArfGAP 2. (740 aa)
	VANGL1	Vang-like protein. (535 aa)
	TRIP10	Thyroid hormone receptor interactor 10. (597 aa)
	ARHGAP1	Rho GTPase activating protein 1. (458 aa)
	CPNE5	Copine 5. (610 aa)
	RHOQ	Ras homolog family member Q. (233 aa)
	GJA1	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (382 aa)
	ANKRD33	Ankyrin repeat domain 33. (452 aa)

Your Current Organism:

Macaca mulatta

NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ANAPC15	CDC42	ENSMMUP00000036848	ENSMMUP00000040537	Late endosomal/lysosomal adaptor, MAPK and MTOR activator 1.	Cell division control protein 42 homolog isoform 1.	0.453
ANAPC15	GIT2	ENSMMUP00000036848	ENSMMUP00000013752	Late endosomal/lysosomal adaptor, MAPK and MTOR activator 1.	GIT ArfGAP 2.	0.483
ANAPC15	PAK2	ENSMMUP00000036848	ENSMMUP00000015786	Late endosomal/lysosomal adaptor, MAPK and MTOR activator 1.	Non-specific serine/threonine protein kinase.	0.433
ANAPC15	RAB7A	ENSMMUP00000036848	ENSMMUP00000065506	Late endosomal/lysosomal adaptor, MAPK and MTOR activator 1.	RAB7A, member RAS oncogene family.	0.536
ANAPC15	RHOQ	ENSMMUP00000036848	ENSMMUP00000007121	Late endosomal/lysosomal adaptor, MAPK and MTOR activator 1.	Ras homolog family member Q.	0.435
ANKRD33	VANGL1	ENSMMUP00000006599	ENSMMUP00000011750	Ankyrin repeat domain 33.	Vang-like protein.	0.436
ANKRD33B	VANGL1	ENSMMUP00000034953	ENSMMUP00000011750	Ankyrin repeat domain 33B.	Vang-like protein.	0.436
ARHGAP1	ARHGEF7	ENSMMUP00000010285	ENSMMUP00000018108	Rho GTPase activating protein 1.	Rho guanine nucleotide exchange factor 7.	0.492
ARHGAP1	CAV3	ENSMMUP00000010285	ENSMMUP00000061270	Rho GTPase activating protein 1.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.415
ARHGAP1	CDC42	ENSMMUP00000010285	ENSMMUP00000040537	Rho GTPase activating protein 1.	Cell division control protein 42 homolog isoform 1.	0.963
ARHGAP1	DEPDC1B	ENSMMUP00000010285	ENSMMUP00000059531	Rho GTPase activating protein 1.	DEP domain-containing protein 1B isoform 1.	0.401
ARHGAP1	DIAPH3	ENSMMUP00000010285	ENSMMUP00000018118	Rho GTPase activating protein 1.	Diaphanous related formin 3.	0.441
ARHGAP1	ENSMMUP00000076986	ENSMMUP00000010285	ENSMMUP00000076986	Rho GTPase activating protein 1.	PHB domain-containing protein.	0.401
ARHGAP1	FMN1	ENSMMUP00000010285	ENSMMUP00000002413	Rho GTPase activating protein 1.	Formin 1.	0.411
ARHGAP1	FMN2	ENSMMUP00000010285	ENSMMUP00000067399	Rho GTPase activating protein 1.	Formin 2.	0.411
ARHGAP1	FNBP1	ENSMMUP00000010285	ENSMMUP00000042852	Rho GTPase activating protein 1.	Formin binding protein 1.	0.454
ARHGAP1	GIT1	ENSMMUP00000010285	ENSMMUP00000057327	Rho GTPase activating protein 1.	GIT ArfGAP 1.	0.435
ARHGAP1	GIT2	ENSMMUP00000010285	ENSMMUP00000013752	Rho GTPase activating protein 1.	GIT ArfGAP 2.	0.438
ARHGAP1	IQGAP1	ENSMMUP00000010285	ENSMMUP00000015598	Rho GTPase activating protein 1.	IQ motif containing GTPase activating protein 1.	0.524
ARHGAP1	IQGAP3	ENSMMUP00000010285	ENSMMUP00000003526	Rho GTPase activating protein 1.	IQ motif containing GTPase activating protein 3.	0.585