STRINGSTRING
ITPR3 ITPR3 TAS2R41 TAS2R41 TAS2R8 TAS2R8 TAS2R39 TAS2R39 TAS2R20 TAS2R20 SCN4B SCN4B TAS2R1 TAS2R1 TAS2R3 TAS2R3 TAS2R7 TAS2R7 TAS2R5 TAS2R5 PLCB2 PLCB2 SCN2B SCN2B TAS2R13 TAS2R13 SCN1B SCN1B SCN3A SCN3A TRPM4 TRPM4 GRM4 GRM4 LOC694161 LOC694161 TAS2R4 TAS2R4 TAS1R1 TAS1R1 GNG13 GNG13 SCN2A SCN2A TAS1R2 TAS1R2 TAS2R40 TAS2R40 GNB3 GNB3 TRPM5 TRPM5 TAS2R10 TAS2R10 CALHM3 CALHM3 TAS2R16 TAS2R16 TAS2R38 TAS2R38 TAS1R3 TAS1R3 GNAT3 GNAT3 CALHM1 CALHM1 GRM1 GRM1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2671 aa)
TAS2R41Taste receptor type 2. (307 aa)
TAS2R8Taste receptor type 2. (318 aa)
TAS2R39Taste receptor type 2 member 39; Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5 (By similarity). (338 aa)
TAS2R20Taste receptor type 2. (309 aa)
SCN4BSodium voltage-gated channel beta subunit 4. (316 aa)
TAS2R1Taste receptor type 2. (299 aa)
TAS2R3Taste receptor type 2. (316 aa)
TAS2R7Taste receptor type 2 member 7; Gustducin-coupled receptor implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. Signals through PLCB2 and the calcium-regulated cation channel TRPM5 (By similarity). (318 aa)
TAS2R5Taste 2 receptor member 5; Belongs to the G-protein coupled receptor T2R family. (386 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1302 aa)
SCN2BSodium voltage-gated channel beta subunit 2. (215 aa)
TAS2R13Taste receptor type 2. (303 aa)
SCN1BSodium voltage-gated channel beta subunit 1. (402 aa)
SCN3ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2000 aa)
TRPM4Transient receptor potential cation channel subfamily M member 4. (1215 aa)
GRM4Glutamate metabotropic receptor 4. (912 aa)
LOC694161Taste receptor type 2. (309 aa)
TAS2R4Taste receptor type 2. (299 aa)
TAS1R1Taste 1 receptor member 1. (841 aa)
GNG13Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (67 aa)
SCN2ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2005 aa)
TAS1R2Taste receptor type 1 member 2; Putative taste receptor. TAS1R2/TAS1R3 recognizes diverse natural and synthetic sweeteners (By similarity). (839 aa)
TAS2R40Taste receptor type 2. (323 aa)
GNB3Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3. (340 aa)
TRPM5Transient receptor potential cation channel subfamily M member 5. (1156 aa)
TAS2R10Taste receptor type 2. (307 aa)
CALHM3Calcium homeostasis modulator 3. (387 aa)
TAS2R16Taste receptor type 2. (291 aa)
TAS2R38Taste receptor type 2. (333 aa)
TAS1R3Taste 1 receptor member 3. (852 aa)
GNAT3G protein subunit alpha transducin 3. (354 aa)
CALHM1Calcium homeostasis modulator 1. (345 aa)
GRM1Metabotropic glutamate receptor 1 isoform alpha. (1195 aa)
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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