STRINGSTRING
APOE APOE GPC4 GPC4 APOA2 APOA2 LRP8 LRP8 APOB APOB PLB1 PLB1 LRP1B LRP1B GPC5 GPC5 SDC3 SDC3 SDC2 SDC2 RBP4 RBP4 BCO2 BCO2 LRP10 LRP10 APOA4 APOA4 APOA1 APOA1 LRP12 LRP12 APOM APOM GPC6 GPC6 GPC3 GPC3 AKR1C1 AKR1C1 AGRN AGRN LDLR LDLR LRP1 LRP1 F6ZWK6_MACMU F6ZWK6_MACMU LRP3 LRP3 BCO1 BCO1 CLPS CLPS AKR1C8P AKR1C8P GPIHBP1 GPIHBP1 RETSAT RETSAT SDC1 SDC1 GPC1 GPC1 GPC2 GPC2 LRAT LRAT LOC722496 LOC722496 SDC4 SDC4 HSPG2 HSPG2 APOC3 APOC3 RDH11 RDH11 LRP2 LRP2 RBP2 RBP2 APOC2 APOC2 TTR TTR
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
APOEApolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...] (317 aa)
GPC4Glypican-4; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (556 aa)
APOA2Truncated apolipoprotein A-II; Apo A-II makes up about 20% of the protein of the HDL (high density lipoprotein) phospholipid-rich fraction in plasma; Belongs to the apolipoprotein A2 family. (100 aa)
LRP8LDL receptor related protein 8. (959 aa)
APOBApolipoprotein B. (4555 aa)
PLB1Phospholipase B1. (1461 aa)
LRP1BLDL receptor related protein 1B. (4599 aa)
GPC5Glypican 5; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (572 aa)
SDC3Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (463 aa)
SDC2Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (201 aa)
RBP4Retinol binding protein 4; Belongs to the calycin superfamily. Lipocalin family. (265 aa)
BCO2Beta-carotene oxygenase 2. (567 aa)
LRP10Low-density lipoprotein receptor-related protein 10. (714 aa)
APOA4Apolipoprotein A4. (441 aa)
APOA1Truncated apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility; Belongs to the apolipoprotein A1/A4/E family. (267 aa)
LRP12Low-density lipoprotein receptor-related protein 12 isoform a. (859 aa)
APOMApolipoprotein M. (188 aa)
GPC6Glypican 6; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (555 aa)
GPC3Glypican 3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (603 aa)
AKR1C1Aldo_ket_red domain-containing protein. (323 aa)
AGRNAgrin. (2067 aa)
LDLRUncharacterized protein. (918 aa)
LRP1LDL receptor related protein 1. (4561 aa)
F6ZWK6_MACMUUncharacterized protein. (3263 aa)
LRP3Low-density lipoprotein receptor-related protein 3. (770 aa)
BCO1Beta,beta-carotene 15,15'-monooxygenase. (547 aa)
CLPSColipase. (112 aa)
AKR1C8PAldo-keto reductase family 1 member C8, pseudogene. (332 aa)
GPIHBP1Uncharacterized protein. (338 aa)
RETSATRetinol saturase. (623 aa)
SDC1Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (505 aa)
GPC1Glypican 1; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (784 aa)
GPC2Glypican 2; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (578 aa)
LRATLRAT domain-containing protein. (230 aa)
LOC722496Aldo_ket_red domain-containing protein. (322 aa)
SDC4Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (198 aa)
HSPG2Heparan sulfate proteoglycan 2. (4680 aa)
APOC3Uncharacterized protein. (256 aa)
RDH11Retinol dehydrogenase 11; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (318 aa)
LRP2LDL receptor related protein 2. (4660 aa)
RBP2FABP domain-containing protein; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (134 aa)
APOC2Uncharacterized protein. (184 aa)
TTRTransthyretin; Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain. (149 aa)
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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