STRINGSTRING
POU5F1 POU5F1 LOC695427-2 LOC695427-2 MYOD1 MYOD1 PLK3 PLK3 MBD1 MBD1 PLK1 PLK1 PAX5 PAX5 PLK2 PLK2 H3-4 H3-4 LOC698105 LOC698105 PLK5 PLK5 FOS FOS LOC703889 LOC703889 LOC100430668 LOC100430668 KLF4 KLF4 LOC695427 LOC695427
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
POU5F1POU domain, class 5, transcription factor 1; Transcription factor that binds to the octamer motif (5'- ATTTGCAT-3'). Forms a trimeric complex with SOX2 or SOX15 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206 (By similarity). Critical for early embryogenesis and for embryonic stem cell pluripotency; Belongs to the POU transcription factor family. Class-5 subfamily. (360 aa)
LOC695427-2Histone H3; Belongs to the histone H3 family. (136 aa)
MYOD1Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (319 aa)
PLK3Serine/threonine-protein kinase PLK. (664 aa)
MBD1Methyl-CpG binding domain protein 1. (974 aa)
PLK1Serine/threonine-protein kinase PLK. (603 aa)
PAX5Paired box 5. (407 aa)
PLK2Serine/threonine-protein kinase PLK. (685 aa)
H3-4Histone H3; Belongs to the histone H3 family. (136 aa)
LOC698105Histone H3.1. (136 aa)
PLK5Serine/threonine-protein kinase PLK. (625 aa)
FOSV-fos FBJ murine osteosarcoma viral oncogene-like protein. (380 aa)
LOC703889Histone H3.1. (136 aa)
LOC100430668Histone H3.1. (136 aa)
KLF4Kruppel like factor 4. (544 aa)
LOC695427Histone H3.1. (136 aa)
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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