STRINGSTRING
CALM3 CALM3 BMP4 BMP4 BMP7 BMP7 IGF1 IGF1 CALML5 CALML5 EPO EPO NTF3 NTF3 LOC717686 LOC717686 CALML6 CALML6 NGF NGF CALML3 CALML3 BDNF BDNF PTH PTH BMP2 BMP2 SOST SOST CALM2 CALM2 ALB ALB
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CALM3Calmodulin 3; Belongs to the calmodulin family. (194 aa)
BMP4Bone morphogenetic protein 4. (408 aa)
BMP7Bone morphogenetic protein 7. (431 aa)
IGF1Insulin like growth factor 1. (208 aa)
CALML5Calmodulin-like protein 5. (146 aa)
EPOErythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. (193 aa)
NTF3Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons; Belongs to the NGF-beta family. (270 aa)
LOC717686Uncharacterized protein; Belongs to the calmodulin family. (105 aa)
CALML6Calmodulin like 6. (181 aa)
NGFNerve growth factor; Belongs to the NGF-beta family. (294 aa)
CALML3Calmodulin-related protein NB-1; Belongs to the calmodulin family. (149 aa)
BDNFBrain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...] (329 aa)
PTHParathyroid hormone; PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion; Belongs to the parathyroid hormone family. (115 aa)
BMP2Bone morphogenetic protein 2. (396 aa)
SOSTSclerostin. (213 aa)
CALM2Uncharacterized protein; Belongs to the calmodulin family. (204 aa)
ALBSerum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...] (608 aa)
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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