18 items (Macaca mulatta) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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Your Input:
	CALML5	Calmodulin-like protein 5. (146 aa)
	JAK2	Tyrosine-protein kinase. (1137 aa)
	CALM3	Calmodulin 3; Belongs to the calmodulin family. (194 aa)
	CALM2	Uncharacterized protein; Belongs to the calmodulin family. (204 aa)
	BCL2	BCL2 apoptosis regulator. (241 aa)
	MAOB	Amine oxidase. (520 aa)
	SNCA	Alpha-synuclein; Neuronal protein that plays several roles in synaptic activity such as regulation of synaptic vesicle trafficking and subsequent neurotransmitter release. Participates as a monomer in synaptic vesicle exocytosis by enhancing vesicle priming, fusion and dilation of exocytotic fusion pores. Mechanistically, acts by increasing local Ca(2+) release from microdomains which is essential for the enhancement of ATP-induced exocytosis. Acts also as a molecular chaperone in its multimeric membrane-bound state, assisting in the folding of synaptic fusion components called SNAREs [...] (146 aa)
	PRKACB	cAMP-dependent protein kinase catalytic subunit beta isoform 1; Belongs to the protein kinase superfamily. (398 aa)
	BDNF	Brain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...] (329 aa)
	PRKACA	Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (431 aa)
	CALML3	Calmodulin-related protein NB-1; Belongs to the calmodulin family. (149 aa)
	PINK1	Serine/threonine-protein kinase PINK1, mitochondrial. (581 aa)
	NGF	Nerve growth factor; Belongs to the NGF-beta family. (294 aa)
	CALML6	Calmodulin like 6. (181 aa)
	LOC717686	Uncharacterized protein; Belongs to the calmodulin family. (105 aa)
	STAT3	Signal transducer and activator of transcription. (871 aa)
	PRKN	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (465 aa)
	PRKACG	cAMP-dependent protein kinase catalytic subunit gamma; Phosphorylates a large number of substrates in the cytoplasm and the nucleus; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cAMP subfamily. (350 aa)

Your Current Organism:

Macaca mulatta

NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BCL2	BDNF	ENSMMUP00000069881	ENSMMUP00000059263	BCL2 apoptosis regulator.	Brain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...]	0.834
BCL2	JAK2	ENSMMUP00000069881	ENSMMUP00000019119	BCL2 apoptosis regulator.	Tyrosine-protein kinase.	0.592
BCL2	NGF	ENSMMUP00000069881	ENSMMUP00000046298	BCL2 apoptosis regulator.	Nerve growth factor; Belongs to the NGF-beta family.	0.541
BCL2	PINK1	ENSMMUP00000069881	ENSMMUP00000052968	BCL2 apoptosis regulator.	Serine/threonine-protein kinase PINK1, mitochondrial.	0.559
BCL2	PRKACA	ENSMMUP00000069881	ENSMMUP00000054168	BCL2 apoptosis regulator.	Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily.	0.430
BCL2	PRKACB	ENSMMUP00000069881	ENSMMUP00000059748	BCL2 apoptosis regulator.	cAMP-dependent protein kinase catalytic subunit beta isoform 1; Belongs to the protein kinase superfamily.	0.483
BCL2	PRKACG	ENSMMUP00000069881	ENSMMUP00000026815	BCL2 apoptosis regulator.	cAMP-dependent protein kinase catalytic subunit gamma; Phosphorylates a large number of substrates in the cytoplasm and the nucleus; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cAMP subfamily.	0.424
BCL2	PRKN	ENSMMUP00000069881	ENSMMUP00000026859	BCL2 apoptosis regulator.	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily.	0.459
BCL2	SNCA	ENSMMUP00000069881	ENSMMUP00000061274	BCL2 apoptosis regulator.	Alpha-synuclein; Neuronal protein that plays several roles in synaptic activity such as regulation of synaptic vesicle trafficking and subsequent neurotransmitter release. Participates as a monomer in synaptic vesicle exocytosis by enhancing vesicle priming, fusion and dilation of exocytotic fusion pores. Mechanistically, acts by increasing local Ca(2+) release from microdomains which is essential for the enhancement of ATP-induced exocytosis. Acts also as a molecular chaperone in its multimeric membrane-bound state, assisting in the folding of synaptic fusion components called SNAREs [...]	0.526
BCL2	STAT3	ENSMMUP00000069881	ENSMMUP00000043986	BCL2 apoptosis regulator.	Signal transducer and activator of transcription.	0.859
BDNF	BCL2	ENSMMUP00000059263	ENSMMUP00000069881	Brain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...]	BCL2 apoptosis regulator.	0.834
BDNF	CALM2	ENSMMUP00000059263	ENSMMUP00000076065	Brain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...]	Uncharacterized protein; Belongs to the calmodulin family.	0.623
BDNF	CALM3	ENSMMUP00000059263	ENSMMUP00000076991	Brain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...]	Calmodulin 3; Belongs to the calmodulin family.	0.623
BDNF	CALML3	ENSMMUP00000059263	ENSMMUP00000053471	Brain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...]	Calmodulin-related protein NB-1; Belongs to the calmodulin family.	0.622
BDNF	CALML5	ENSMMUP00000059263	ENSMMUP00000022969	Brain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...]	Calmodulin-like protein 5.	0.623
BDNF	CALML6	ENSMMUP00000059263	ENSMMUP00000045683	Brain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...]	Calmodulin like 6.	0.632
BDNF	JAK2	ENSMMUP00000059263	ENSMMUP00000019119	Brain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...]	Tyrosine-protein kinase.	0.441
BDNF	LOC717686	ENSMMUP00000059263	ENSMMUP00000045604	Brain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...]	Uncharacterized protein; Belongs to the calmodulin family.	0.623
BDNF	MAOB	ENSMMUP00000059263	ENSMMUP00000069352	Brain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...]	Amine oxidase.	0.671
BDNF	NGF	ENSMMUP00000059263	ENSMMUP00000046298	Brain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...]	Nerve growth factor; Belongs to the NGF-beta family.	0.910