STRINGSTRING
BDNF BDNF SIK2 SIK2 CREBBP CREBBP CALM2 CALM2 TXNIP TXNIP CALM3 CALM3 DAPK1 DAPK1 CALML5 CALML5 FOXO1 FOXO1 LOC717686 LOC717686 CALML6 CALML6 CALML3 CALML3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
BDNFBrain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...] (329 aa)
SIK2Salt inducible kinase 2. (1077 aa)
CREBBPCREB-binding protein isoform a. (2442 aa)
CALM2Uncharacterized protein; Belongs to the calmodulin family. (204 aa)
TXNIPThioredoxin-interacting protein. (391 aa)
CALM3Calmodulin 3; Belongs to the calmodulin family. (194 aa)
DAPK1Uncharacterized protein. (1440 aa)
CALML5Calmodulin-like protein 5. (146 aa)
FOXO1Forkhead box O1. (655 aa)
LOC717686Uncharacterized protein; Belongs to the calmodulin family. (105 aa)
CALML6Calmodulin like 6. (181 aa)
CALML3Calmodulin-related protein NB-1; Belongs to the calmodulin family. (149 aa)
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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