STRINGSTRING
ASCL2 ASCL2 KCNG1 KCNG1 PMEPA1 PMEPA1 GRM1 GRM1 TAC1 TAC1 VAMP1 VAMP1 CNOT9 CNOT9 SYT2 SYT2 SCN1B SCN1B KCNA1 KCNA1 CORO1A CORO1A CACNA1H CACNA1H SCN1A SCN1A STX1A STX1A EGFR EGFR SSTR1 SSTR1 SCN7A SCN7A ESRRG ESRRG RPGR RPGR GPRIN1 GPRIN1 CPLX3 CPLX3 CACNA2D2 CACNA2D2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ASCL2Achaete-scute family bHLH transcription factor 2. (193 aa)
KCNG1Potassium voltage-gated channel modifier subfamily G member 1; Belongs to the potassium channel family. (513 aa)
PMEPA1Prostate transmembrane protein, androgen induced 1. (287 aa)
GRM1Metabotropic glutamate receptor 1 isoform alpha. (1195 aa)
TAC1Tachykinin precursor 1. (246 aa)
VAMP1Vesicle-associated membrane protein 2; Involved in the targeting and/or fusion of transport vesicles to their target membrane. Modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1. Belongs to the synaptobrevin family. (118 aa)
CNOT9Phosphoinositide phospholipase C. (1065 aa)
SYT2Synaptotagmin 2. (470 aa)
SCN1BSodium voltage-gated channel beta subunit 1. (402 aa)
KCNA1Voltage-gated potassium channel subunit Kv1.1; Belongs to the potassium channel family. (495 aa)
CORO1ACoronin; Belongs to the WD repeat coronin family. (461 aa)
CACNA1HCalcium voltage-gated channel subunit alpha1 H. (2352 aa)
SCN1ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2008 aa)
STX1ASyntaxin-1A isoform 1; Belongs to the syntaxin family. (288 aa)
EGFREpidermal growth factor receptor; Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, AREG, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. Activates at least [...] (1210 aa)
SSTR1Somatostatin receptor type 1; Belongs to the G-protein coupled receptor 1 family. (391 aa)
SCN7ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1977 aa)
ESRRGEstrogen related receptor gamma. (470 aa)
RPGRRetinitis pigmentosa GTPase regulator. (811 aa)
GPRIN1G protein regulated inducer of neurite outgrowth 1. (962 aa)
CPLX3Complexin III. (158 aa)
CACNA2D2Calcium voltage-gated channel auxiliary subunit alpha2delta 2. (1153 aa)
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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