35 items (Macaca mulatta) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC695427-2	Histone H3; Belongs to the histone H3 family. (136 aa)
	BRD8	Bromodomain containing 8. (1235 aa)
	HDAC1	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (482 aa)
	CAV1	Caveolin 1. (303 aa)
	LOC699443	Histone H3; Belongs to the histone H3 family. (136 aa)
	EP400	E1A binding protein p400. (3045 aa)
	ANP32E	Acidic leucine-rich nuclear phosphoprotein 32 family member E isoform 1. (267 aa)
	RUVBL1	RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (456 aa)
	LOC699317	Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
	DMAP1	DNA methyltransferase 1 associated protein 1. (612 aa)
	LOC106996511	Histone H4. (103 aa)
	LOC710748	Histone H3; Belongs to the histone H3 family. (136 aa)
	TRRAP	Transformation/transcription domain associated protein; Belongs to the PI3/PI4-kinase family. (3873 aa)
	LOC114669830	Histone H3; Belongs to the histone H3 family. (136 aa)
	ING4	Inhibitor of growth protein. (246 aa)
	LOC106996511-2	Histone H4. (103 aa)
	H3-4	Histone H3; Belongs to the histone H3 family. (136 aa)
	LOC106996511-3	Histone H4. (103 aa)
	LOC697115	Histone H4. (103 aa)
	LOC106996511-4	Histone H4. (103 aa)
	ING5	Inhibitor of growth protein. (240 aa)
	LOC693939	Histone H3; Belongs to the histone H3 family. (136 aa)
	ENSMMUP00000068277	Histone H3; Belongs to the histone H3 family. (136 aa)
	LOC106996511-5	Histone H4. (103 aa)
	LOC718280	Histone domain-containing protein. (136 aa)
	LOC698354	Histone H4. (103 aa)
	LOC106996511-6	Histone H4. (103 aa)
	MEAF6	MYST/Esa1 associated factor 6. (203 aa)
	LOC704341	Histone H4. (103 aa)
	ING3	Inhibitor of growth protein. (418 aa)
	LOC695323	Histone H4. (103 aa)
	LOC699110	Histone H4. (103 aa)
	LOC697721	Histone H4. (103 aa)
	ARG2	Arginase. (417 aa)
	EPC1	Enhancer of polycomb homolog. (836 aa)

Your Current Organism:

Macaca mulatta

NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ANP32E	BRD8	ENSMMUP00000028354	ENSMMUP00000002006	Acidic leucine-rich nuclear phosphoprotein 32 family member E isoform 1.	Bromodomain containing 8.	0.745
ANP32E	DMAP1	ENSMMUP00000028354	ENSMMUP00000040336	Acidic leucine-rich nuclear phosphoprotein 32 family member E isoform 1.	DNA methyltransferase 1 associated protein 1.	0.773
ANP32E	EP400	ENSMMUP00000028354	ENSMMUP00000023322	Acidic leucine-rich nuclear phosphoprotein 32 family member E isoform 1.	E1A binding protein p400.	0.833
ANP32E	ING3	ENSMMUP00000028354	ENSMMUP00000073053	Acidic leucine-rich nuclear phosphoprotein 32 family member E isoform 1.	Inhibitor of growth protein.	0.418
ANP32E	MEAF6	ENSMMUP00000028354	ENSMMUP00000070241	Acidic leucine-rich nuclear phosphoprotein 32 family member E isoform 1.	MYST/Esa1 associated factor 6.	0.756
ANP32E	RUVBL1	ENSMMUP00000028354	ENSMMUP00000038963	Acidic leucine-rich nuclear phosphoprotein 32 family member E isoform 1.	RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding.	0.687
ANP32E	TRRAP	ENSMMUP00000028354	ENSMMUP00000053140	Acidic leucine-rich nuclear phosphoprotein 32 family member E isoform 1.	Transformation/transcription domain associated protein; Belongs to the PI3/PI4-kinase family.	0.464
BRD8	ANP32E	ENSMMUP00000002006	ENSMMUP00000028354	Bromodomain containing 8.	Acidic leucine-rich nuclear phosphoprotein 32 family member E isoform 1.	0.745
BRD8	DMAP1	ENSMMUP00000002006	ENSMMUP00000040336	Bromodomain containing 8.	DNA methyltransferase 1 associated protein 1.	0.976
BRD8	EP400	ENSMMUP00000002006	ENSMMUP00000023322	Bromodomain containing 8.	E1A binding protein p400.	0.984
BRD8	EPC1	ENSMMUP00000002006	ENSMMUP00000078687	Bromodomain containing 8.	Enhancer of polycomb homolog.	0.842
BRD8	ING3	ENSMMUP00000002006	ENSMMUP00000073053	Bromodomain containing 8.	Inhibitor of growth protein.	0.935
BRD8	MEAF6	ENSMMUP00000002006	ENSMMUP00000070241	Bromodomain containing 8.	MYST/Esa1 associated factor 6.	0.980
BRD8	RUVBL1	ENSMMUP00000002006	ENSMMUP00000038963	Bromodomain containing 8.	RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding.	0.949
BRD8	TRRAP	ENSMMUP00000002006	ENSMMUP00000053140	Bromodomain containing 8.	Transformation/transcription domain associated protein; Belongs to the PI3/PI4-kinase family.	0.973
DMAP1	ANP32E	ENSMMUP00000040336	ENSMMUP00000028354	DNA methyltransferase 1 associated protein 1.	Acidic leucine-rich nuclear phosphoprotein 32 family member E isoform 1.	0.773
DMAP1	BRD8	ENSMMUP00000040336	ENSMMUP00000002006	DNA methyltransferase 1 associated protein 1.	Bromodomain containing 8.	0.976
DMAP1	EP400	ENSMMUP00000040336	ENSMMUP00000023322	DNA methyltransferase 1 associated protein 1.	E1A binding protein p400.	0.988
DMAP1	EPC1	ENSMMUP00000040336	ENSMMUP00000078687	DNA methyltransferase 1 associated protein 1.	Enhancer of polycomb homolog.	0.968
DMAP1	HDAC1	ENSMMUP00000040336	ENSMMUP00000013015	DNA methyltransferase 1 associated protein 1.	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.439