STRINGSTRING
ANGPTL8 ANGPTL8 PPY PPY DAPL1 DAPL1 SLC1A5 SLC1A5 MTOR MTOR GCG GCG ANGPTL4 ANGPTL4 SLC7A2 SLC7A2 SLC25A22 SLC25A22 GCGR GCGR SLC1A6 SLC1A6 INS INS SLC1A2 SLC1A2 TCF7L2 TCF7L2 SLC38A4 SLC38A4 SLC38A3 SLC38A3 LAMP1 LAMP1 SLC1A7 SLC1A7 SLC3A1 SLC3A1 SLC1A3 SLC1A3 ALB ALB SST SST
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ANGPTL8Angiopoietin like 8. (198 aa)
PPYPancreatic hormone; Pancreatic hormone is synthesized in pancreatic islets of Langerhans and acts as a regulator of pancreatic and gastrointestinal functions; Belongs to the NPY family. (122 aa)
DAPL1Death associated protein like 1. (107 aa)
SLC1A5Amino acid transporter. (542 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2541 aa)
GCGGlucagon. (263 aa)
ANGPTL4Angiopoietin like 4. (489 aa)
SLC7A2Solute carrier family 7 member 2. (658 aa)
SLC25A22Solute carrier family 25 member 22; Belongs to the mitochondrial carrier (TC 2.A.29) family. (488 aa)
GCGRGlucagon receptor; Belongs to the G-protein coupled receptor 2 family. (491 aa)
SLC1A6Amino acid transporter. (564 aa)
INSInsulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (110 aa)
SLC1A2Amino acid transporter. (611 aa)
TCF7L2Transcription factor 7 like 2. (632 aa)
SLC38A4Na(+)-coupled neutral amino acid transporter 4. (547 aa)
SLC38A3Sodium-coupled neutral amino acid transporter 3. (504 aa)
LAMP1Lysosomal associated membrane protein 1. (733 aa)
SLC1A7Amino acid transporter. (619 aa)
SLC3A1Solute carrier family 3 member 1. (685 aa)
SLC1A3Amino acid transporter. (549 aa)
ALBSerum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...] (608 aa)
SSTSomatostatin preproprotein. (116 aa)
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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