STRINGSTRING
SLC1A5 SLC1A5 IRS1 IRS1 SLC1A6 SLC1A6 INS INS SLC1A2 SLC1A2 FOXO1 FOXO1 EIF4E EIF4E SLC1A7 SLC1A7 SLC1A3 SLC1A3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SLC1A5Amino acid transporter. (542 aa)
IRS1Insulin receptor substrate 1. (1253 aa)
SLC1A6Amino acid transporter. (564 aa)
INSInsulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (110 aa)
SLC1A2Amino acid transporter. (611 aa)
FOXO1Forkhead box O1. (655 aa)
EIF4EUncharacterized protein. (247 aa)
SLC1A7Amino acid transporter. (619 aa)
SLC1A3Amino acid transporter. (549 aa)
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
Server load: low (12%) [HD]