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EGFR | Epidermal growth factor receptor; Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, AREG, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. Activates at least [...] (1210 aa) | ||||
CD44 | Phagocytic glycoprotein I. (742 aa) | ||||
SLC1A3 | Amino acid transporter. (549 aa) | ||||
SLC1A7 | Amino acid transporter. (619 aa) | ||||
LYVE1 | Lymphatic vessel endothelial hyaluronan receptor 1. (321 aa) | ||||
SLC1A2 | Amino acid transporter. (611 aa) | ||||
SLC1A6 | Amino acid transporter. (564 aa) | ||||
SLC1A5 | Amino acid transporter. (542 aa) |