STRINGSTRING
EGFR EGFR CD44 CD44 SLC1A3 SLC1A3 SLC1A7 SLC1A7 LYVE1 LYVE1 SLC1A2 SLC1A2 SLC1A6 SLC1A6 SLC1A5 SLC1A5
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
EGFREpidermal growth factor receptor; Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, AREG, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. Activates at least [...] (1210 aa)
CD44Phagocytic glycoprotein I. (742 aa)
SLC1A3Amino acid transporter. (549 aa)
SLC1A7Amino acid transporter. (619 aa)
LYVE1Lymphatic vessel endothelial hyaluronan receptor 1. (321 aa)
SLC1A2Amino acid transporter. (611 aa)
SLC1A6Amino acid transporter. (564 aa)
SLC1A5Amino acid transporter. (542 aa)
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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