STRINGSTRING
MAP2 MAP2 EGF EGF IGF1 IGF1 GAPDHS GAPDHS GAP43 GAP43 SLC17A7 SLC17A7 NES NES NTF3 NTF3 MBP MBP GFAP GFAP BDNF BDNF PXDN PXDN SYP SYP PXDNL PXDNL FGF1 FGF1 FOS FOS CLIP3 CLIP3 HGF HGF TH TH GAPDH GAPDH
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MAP2Microtubule-associated protein. (1827 aa)
EGFPro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1213 aa)
IGF1Insulin like growth factor 1. (208 aa)
GAPDHSGlyceraldehyde-3-phosphate dehydrogenase. (409 aa)
GAP43Growth associated protein 43. (238 aa)
SLC17A7Solute carrier family 17 member 7. (560 aa)
NESNestin; Belongs to the intermediate filament family. (1721 aa)
NTF3Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons; Belongs to the NGF-beta family. (270 aa)
MBPMyelin basic protein. (437 aa)
GFAPGlial fibrillary acidic protein; Belongs to the intermediate filament family. (462 aa)
BDNFBrain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...] (329 aa)
PXDNPeroxidasin. (1533 aa)
SYPSynaptophysin. (401 aa)
PXDNLPeroxidasin like. (1428 aa)
FGF1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
FOSV-fos FBJ murine osteosarcoma viral oncogene-like protein. (380 aa)
CLIP3Cytoplasmic linker protein 170-related 59 kDa protein. (547 aa)
HGFHepatocyte growth factor; Belongs to the peptidase S1 family. (788 aa)
THTyrosine hydroxylase. (501 aa)
GAPDHGlyceraldehyde-3-phosphate dehydrogenase. (335 aa)
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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