41 items (Macaca mulatta) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PRUNE2	Prune homolog 2 with BCH domain. (3119 aa)
	GNGT1	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
	MEF2C	Myocyte-specific enhancer factor 2C isoform 1. (473 aa)
	CC2D2A	Coiled-coil and C2 domain containing 2A. (1620 aa)
	VSX2	Visual system homeobox 2. (361 aa)
	EEF1A1	Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (462 aa)
	NR2E3	Nuclear receptor subfamily 2 group E member 3. (410 aa)
	MYL4	Myosin light chain 4. (195 aa)
	CNGB1	Cyclic nucleotide-binding domain-containing protein. (1247 aa)
	CNGB3	Cyclic nucleotide gated channel subunit beta 3. (808 aa)
	POU5F1	POU domain, class 5, transcription factor 1; Transcription factor that binds to the octamer motif (5'- ATTTGCAT-3'). Forms a trimeric complex with SOX2 or SOX15 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206 (By similarity). Critical for early embryogenesis and for embryonic stem cell pluripotency; Belongs to the POU transcription factor family. Class-5 subfamily. (360 aa)
	PDE6C	Phosphodiesterase. (858 aa)
	ARR3	Arrestin 3. (388 aa)
	PTPRZ1	Uncharacterized protein. (2319 aa)
	IRX6	Iroquois homeobox 6. (445 aa)
	MYH4	Myosin heavy chain 4; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1939 aa)
	GRK7	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (553 aa)
	GNAT2	G protein subunit alpha transducin 2. (354 aa)
	GNAI3	Guanine nucleotide-binding protein G(K) subunit alpha. (354 aa)
	GNB3	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3. (340 aa)
	KIF2A	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (744 aa)
	VSX1	Visual system homeobox 1. (365 aa)
	TMSB10	Uncharacterized protein. (148 aa)
	CCDC136	Coiled-coil domain containing 136. (1208 aa)
	THRB	Thyroid hormone receptor beta. (524 aa)
	B2M	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity). (119 aa)
	KLF4	Kruppel like factor 4. (544 aa)
	GUCA1C	Guanylate cyclase activator 1C. (210 aa)
	BMP4	Bone morphogenetic protein 4. (408 aa)
	ROM1	Rod outer segment membrane protein 1. (351 aa)
	NRL	Neural retina leucine zipper. (239 aa)
	CNGA1	Cyclic nucleotide gated channel subunit alpha 1. (759 aa)
	KIF21A	Kinesin family member 21A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1674 aa)
	NUP93	Nuclear pore complex protein Nup93; Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance; Belongs to the nucleoporin interacting component (NIC) family. (819 aa)
	SAMD7	Sterile alpha motif domain containing 7. (446 aa)
	CRX	Cone-rod homeobox. (299 aa)
	OTX2	Orthodenticle homeobox 2. (289 aa)
	PDE6H	Phosphodiesterase 6H. (85 aa)
	SLC12A6	Solute carrier family 12 member 6 isoform a. (1150 aa)
	GNB1	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1. (340 aa)
	PDRG1	P53 and DNA damage-regulated protein 1. (133 aa)

Your Current Organism:

Macaca mulatta

NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARR3	CNGA1	ENSMMUP00000018315	ENSMMUP00000050524	Arrestin 3.	Cyclic nucleotide gated channel subunit alpha 1.	0.624
ARR3	CNGB1	ENSMMUP00000018315	ENSMMUP00000024114	Arrestin 3.	Cyclic nucleotide-binding domain-containing protein.	0.480
ARR3	CNGB3	ENSMMUP00000018315	ENSMMUP00000023519	Arrestin 3.	Cyclic nucleotide gated channel subunit beta 3.	0.680
ARR3	CRX	ENSMMUP00000018315	ENSMMUP00000062943	Arrestin 3.	Cone-rod homeobox.	0.611
ARR3	GNAT2	ENSMMUP00000018315	ENSMMUP00000007670	Arrestin 3.	G protein subunit alpha transducin 2.	0.656
ARR3	GNB1	ENSMMUP00000018315	ENSMMUP00000066781	Arrestin 3.	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1.	0.559
ARR3	GNB3	ENSMMUP00000018315	ENSMMUP00000006868	Arrestin 3.	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3.	0.770
ARR3	GNGT1	ENSMMUP00000018315	ENSMMUP00000048892	Arrestin 3.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.719
ARR3	GRK7	ENSMMUP00000018315	ENSMMUP00000009694	Arrestin 3.	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.	0.732
ARR3	GUCA1C	ENSMMUP00000018315	ENSMMUP00000076844	Arrestin 3.	Guanylate cyclase activator 1C.	0.727
ARR3	NR2E3	ENSMMUP00000018315	ENSMMUP00000025333	Arrestin 3.	Nuclear receptor subfamily 2 group E member 3.	0.475
ARR3	NRL	ENSMMUP00000018315	ENSMMUP00000079996	Arrestin 3.	Neural retina leucine zipper.	0.449
ARR3	PDE6C	ENSMMUP00000018315	ENSMMUP00000019304	Arrestin 3.	Phosphodiesterase.	0.778
ARR3	PDE6H	ENSMMUP00000018315	ENSMMUP00000065383	Arrestin 3.	Phosphodiesterase 6H.	0.753
ARR3	ROM1	ENSMMUP00000018315	ENSMMUP00000079457	Arrestin 3.	Rod outer segment membrane protein 1.	0.515
ARR3	VSX1	ENSMMUP00000018315	ENSMMUP00000071078	Arrestin 3.	Visual system homeobox 1.	0.535
ARR3	VSX2	ENSMMUP00000018315	ENSMMUP00000032733	Arrestin 3.	Visual system homeobox 2.	0.562
BMP4	KLF4	ENSMMUP00000077296	ENSMMUP00000076676	Bone morphogenetic protein 4.	Kruppel like factor 4.	0.620
BMP4	OTX2	ENSMMUP00000077296	ENSMMUP00000063685	Bone morphogenetic protein 4.	Orthodenticle homeobox 2.	0.499
BMP4	POU5F1	ENSMMUP00000077296	ENSMMUP00000020597	Bone morphogenetic protein 4.	POU domain, class 5, transcription factor 1; Transcription factor that binds to the octamer motif (5'- ATTTGCAT-3'). Forms a trimeric complex with SOX2 or SOX15 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206 (By similarity). Critical for early embryogenesis and for embryonic stem cell pluripotency; Belongs to the POU transcription factor family. Class-5 subfamily.	0.782