6 items (Macaca mulatta) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	RUNX1	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (480 aa)
	COL2A1	Collagen type II alpha 1 chain. (1487 aa)
	HOXD8	Homeobox D8. (292 aa)
	HOXD10	Homeobox D10. (340 aa)
	HOXD9	Homeobox D9. (345 aa)
	RUNX3	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (428 aa)

Your Current Organism:

Macaca mulatta

NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
COL2A1	HOXD10	ENSMMUP00000015024	ENSMMUP00000043699	Collagen type II alpha 1 chain.	Homeobox D10.	0.725
COL2A1	HOXD8	ENSMMUP00000015024	ENSMMUP00000030941	Collagen type II alpha 1 chain.	Homeobox D8.	0.741
COL2A1	HOXD9	ENSMMUP00000015024	ENSMMUP00000045547	Collagen type II alpha 1 chain.	Homeobox D9.	0.749
COL2A1	RUNX3	ENSMMUP00000015024	ENSMMUP00000061630	Collagen type II alpha 1 chain.	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.	0.629
HOXD10	COL2A1	ENSMMUP00000043699	ENSMMUP00000015024	Homeobox D10.	Collagen type II alpha 1 chain.	0.725
HOXD10	HOXD9	ENSMMUP00000043699	ENSMMUP00000045547	Homeobox D10.	Homeobox D9.	0.767
HOXD8	COL2A1	ENSMMUP00000030941	ENSMMUP00000015024	Homeobox D8.	Collagen type II alpha 1 chain.	0.741
HOXD8	HOXD9	ENSMMUP00000030941	ENSMMUP00000045547	Homeobox D8.	Homeobox D9.	0.485
HOXD9	COL2A1	ENSMMUP00000045547	ENSMMUP00000015024	Homeobox D9.	Collagen type II alpha 1 chain.	0.749
HOXD9	HOXD10	ENSMMUP00000045547	ENSMMUP00000043699	Homeobox D9.	Homeobox D10.	0.767
HOXD9	HOXD8	ENSMMUP00000045547	ENSMMUP00000030941	Homeobox D9.	Homeobox D8.	0.485
RUNX1	RUNX3	ENSMMUP00000075631	ENSMMUP00000061630	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.	0.570
RUNX3	COL2A1	ENSMMUP00000061630	ENSMMUP00000015024	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.	Collagen type II alpha 1 chain.	0.629
RUNX3	RUNX1	ENSMMUP00000061630	ENSMMUP00000075631	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.	0.570