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IL1B | Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. (268 aa) | ||||
LPIN1 | Lipin 1. (975 aa) | ||||
ARF1 | Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family. (217 aa) | ||||
COL8A1 | Collagen type VIII alpha 1 chain. (746 aa) | ||||
ITGB2 | Integrin beta. (911 aa) | ||||
MSMO1 | C-4 methylsterol oxidase isoform 1; Belongs to the sterol desaturase family. (293 aa) | ||||
SC5D | Lathosterol oxidase; Belongs to the sterol desaturase family. (299 aa) | ||||
CASP3 | Caspase 3; Belongs to the peptidase C14A family. (277 aa) | ||||
DDIT3 | DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] (192 aa) | ||||
ANGPTL4 | Angiopoietin like 4. (489 aa) | ||||
NSDHL | Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating; Belongs to the 3-beta-HSD family. (373 aa) | ||||
RPE65 | Retinoid isomerohydrolase RPE65. (533 aa) | ||||
CASP1 | Caspase 1; Belongs to the peptidase C14A family. (462 aa) | ||||
PDGFB | Platelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (265 aa) | ||||
PLIN2 | Perilipin; Belongs to the perilipin family. (479 aa) | ||||
ABCA1 | ATP binding cassette subfamily A member 1. (2266 aa) | ||||
FDFT1 | Uncharacterized protein. (468 aa) | ||||
COL1A2 | Collagen type I alpha 2 chain. (1274 aa) | ||||
IGFBP5 | Insulin-like growth factor-binding protein 5. (272 aa) | ||||
NCAM1 | Neural cell adhesion molecule 1. (1119 aa) | ||||
ADIPOQ | Adiponectin, C1Q and collagen domain containing. (274 aa) | ||||
FGF10 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa) | ||||
LDLR | Uncharacterized protein. (918 aa) | ||||
IL6 | Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...] (266 aa) | ||||
APOE | Apolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...] (317 aa) | ||||
COL3A1 | Collagen alpha-1(III) chain preproprotein. (1466 aa) | ||||
HSD17B7 | Hydroxysteroid 17-beta dehydrogenase 7. (341 aa) | ||||
LAMA3 | Laminin subunit alpha 3. (3333 aa) | ||||
TLR4 | Toll like receptor 4; Belongs to the Toll-like receptor family. (826 aa) | ||||
CD274 | CD274 molecule. (299 aa) | ||||
THBS3 | Uncharacterized protein. (956 aa) | ||||
CLDN16 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (235 aa) | ||||
CASP8 | Caspase 8; Belongs to the peptidase C14A family. (538 aa) | ||||
CDH3 | Cadherin 3; Cadherins are calcium-dependent cell adhesion proteins. (829 aa) | ||||
GSDMD | Gasdermin D. (529 aa) | ||||
COL16A1 | Collagen type XVI alpha 1 chain. (1604 aa) | ||||
PDK4 | Protein-serine/threonine kinase. (411 aa) | ||||
COL5A2 | Collagen type V alpha 2 chain. (1499 aa) | ||||
ACADS | Uncharacterized protein. (415 aa) | ||||
CREB3L1 | Cyclic AMP-responsive element-binding protein 3-like protein 1. (519 aa) | ||||
ACSS2 | Uncharacterized protein. (714 aa) | ||||
TNFRSF10A | TNF receptor superfamily member 10a. (471 aa) | ||||
SLC25A20 | Mitochondrial carnitine/acylcarnitine carrier protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (301 aa) | ||||
COL17A1 | Collagen type XVII alpha 1 chain. (1455 aa) | ||||
LAMC1 | Laminin subunit gamma-1. (1608 aa) | ||||
CAV1 | Caveolin 1. (303 aa) | ||||
IGFBP3 | Insulin-like growth factor-binding protein 3 isoform b. (291 aa) | ||||
FLNA | Filamin-A isoform 2. (2647 aa) | ||||
FASN | Fatty acid synthase. (2576 aa) | ||||
CDH10 | Cadherin-10 preproprotein; Cadherins are calcium-dependent cell adhesion proteins. (788 aa) | ||||
ACADVL | Acyl-CoA dehydrogenase very long chain. (655 aa) | ||||
RHOJ | Rho-related GTP-binding protein RhoJ. (214 aa) | ||||
FLNC | Filamin C. (2725 aa) | ||||
HMGCR | 3-hydroxy-3-methylglutaryl coenzyme A reductase. (888 aa) | ||||
COL9A1 | Collagen type IX alpha 1 chain. (921 aa) | ||||
COL11A1 | Collagen alpha-1(XI) chain isoform A preproprotein. (1806 aa) | ||||
ITGA5 | Integrin subunit alpha 5; Belongs to the integrin alpha chain family. (1049 aa) | ||||
SQLE | Squalene monooxygenase. (574 aa) | ||||
CPT1A | Carnitine palmitoyltransferase 1A; Belongs to the carnitine/choline acetyltransferase family. (809 aa) | ||||
COL1A1 | Collagen alpha-1(I) chain preproprotein. (1464 aa) | ||||
FLNB | Filamin B. (2633 aa) |