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BDNF BDNF CALML3 CALML3 EEF2 EEF2 CALML6 CALML6 LOC717686 LOC717686 INS INS CALML5 CALML5 GAPDH GAPDH SYN3 SYN3 ALB ALB SYN2 SYN2 CALM3 CALM3 CALM2 CALM2 FOS FOS SYN1 SYN1 EEF2K EEF2K
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
BDNFBrain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...] (329 aa)
CALML3Calmodulin-related protein NB-1; Belongs to the calmodulin family. (149 aa)
EEF2Elongation factor 2. (858 aa)
CALML6Calmodulin like 6. (181 aa)
LOC717686Uncharacterized protein; Belongs to the calmodulin family. (105 aa)
INSInsulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (110 aa)
CALML5Calmodulin-like protein 5. (146 aa)
GAPDHGlyceraldehyde-3-phosphate dehydrogenase. (335 aa)
SYN3Synapsin III. (580 aa)
ALBSerum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...] (608 aa)
SYN2Synapsin II. (584 aa)
CALM3Calmodulin 3; Belongs to the calmodulin family. (194 aa)
CALM2Uncharacterized protein; Belongs to the calmodulin family. (204 aa)
FOSV-fos FBJ murine osteosarcoma viral oncogene-like protein. (380 aa)
SYN1Synapsin-1 isoform Ia. (705 aa)
EEF2KEukaryotic elongation factor 2 kinase. (725 aa)
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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