Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of proteins in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AGRP | BDNF | ENSMMUP00000071178 | ENSMMUP00000059263 | Agouti related neuropeptide. | Brain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...] | 0.563 |
| AGRP | ESR1 | ENSMMUP00000071178 | ENSMMUP00000069490 | Agouti related neuropeptide. | Estrogen receptor; Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Ligand-dependent nuclear transactivation involves either direct homodimer binding to a palindromic estrogen response element (ERE) sequence or association with other DNA-binding transcription factors, such as AP-1/c-Jun, c-Fos, ATF-2, Sp1 and Sp3, to mediate ERE- independent signaling. Ligand binding induces a conformational change allowing subsequent or combinatorial a [...] | 0.477 |
| AGRP | FOS | ENSMMUP00000071178 | ENSMMUP00000071593 | Agouti related neuropeptide. | V-fos FBJ murine osteosarcoma viral oncogene-like protein. | 0.761 |
| AGRP | GHRH | ENSMMUP00000071178 | ENSMMUP00000037888 | Agouti related neuropeptide. | Growth hormone releasing hormone. | 0.803 |
| AGRP | GHRL | ENSMMUP00000071178 | ENSMMUP00000062710 | Agouti related neuropeptide. | Ghrelin and obestatin prepropeptide. | 0.934 |
| AGRP | GNRH1 | ENSMMUP00000071178 | ENSMMUP00000032173 | Agouti related neuropeptide. | GnRH-associated peptide 1; Stimulates the secretion of gonadotropins; it stimulates the secretion of both luteinizing and follicle-stimulating hormones; Belongs to the GnRH family. | 0.412 |
| AGRP | LEP | ENSMMUP00000071178 | ENSMMUP00000007035 | Agouti related neuropeptide. | Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways (By similarity). In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo-pituitary-adrenal hormones. In the periphery, inc [...] | 0.946 |
| AGRP | MPO | ENSMMUP00000071178 | ENSMMUP00000003023 | Agouti related neuropeptide. | Myeloperoxidase. | 0.549 |
| AGRP | NPY | ENSMMUP00000071178 | ENSMMUP00000070707 | Agouti related neuropeptide. | C-flanking peptide of NPY; NPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone. | 0.955 |
| AGRP | POMC | ENSMMUP00000071178 | ENSMMUP00000075833 | Agouti related neuropeptide. | Uncharacterized protein. | 0.967 |
| AGRP | SST | ENSMMUP00000071178 | ENSMMUP00000001145 | Agouti related neuropeptide. | Somatostatin preproprotein. | 0.510 |
| AGRP | STAT3 | ENSMMUP00000071178 | ENSMMUP00000043986 | Agouti related neuropeptide. | Signal transducer and activator of transcription. | 0.532 |
| AGRP | TH | ENSMMUP00000071178 | ENSMMUP00000005218 | Agouti related neuropeptide. | Tyrosine hydroxylase. | 0.643 |
| AGRP | TRH | ENSMMUP00000071178 | ENSMMUP00000054618 | Agouti related neuropeptide. | Pro-thyrotropin-releasing hormone; Functions as a regulator of the biosynthesis of TSH in the anterior pituitary gland and as a neurotransmitter/ neuromodulator in the central and peripheral nervous systems. | 0.778 |
| ANGPT1 | BDNF | ENSMMUP00000023343 | ENSMMUP00000059263 | Angiopoietin-1 isoform 1. | Brain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...] | 0.408 |
| ANGPT1 | EGF | ENSMMUP00000023343 | ENSMMUP00000013132 | Angiopoietin-1 isoform 1. | Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. | 0.466 |
| ANGPT1 | EPO | ENSMMUP00000023343 | ENSMMUP00000030108 | Angiopoietin-1 isoform 1. | Erythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. | 0.453 |
| ANGPT1 | FGF10 | ENSMMUP00000023343 | ENSMMUP00000053581 | Angiopoietin-1 isoform 1. | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. | 0.454 |
| ANGPT1 | FGF2 | ENSMMUP00000023343 | ENSMMUP00000009729 | Angiopoietin-1 isoform 1. | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. | 0.633 |
| ANGPT1 | FGFR2 | ENSMMUP00000023343 | ENSMMUP00000048184 | Angiopoietin-1 isoform 1. | Fibroblast growth factor receptor. | 0.748 |
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