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ALB ALB FOXP2 FOXP2 MRGPRD MRGPRD SCN10A SCN10A SCN7A SCN7A JAK1 JAK1 SCN11A SCN11A TRPC3 TRPC3 TRPV1 TRPV1 IL31RA IL31RA NTRK3 NTRK3 APOE APOE TRPM8 TRPM8 TRPA1 TRPA1 S1PR3 S1PR3 SCN1A SCN1A ETV1 ETV1 SNAP25 SNAP25 SCN1B SCN1B NEFH NEFH IL31 IL31 PVALB PVALB SDF4 SDF4 GPR26 GPR26 MRGPRX1 MRGPRX1 ADCYAP1 ADCYAP1 PIEZO2 PIEZO2 TMEM100 TMEM100 OSMR OSMR NTRK2 NTRK2 NPPB NPPB QKI QKI
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ALBSerum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...] (608 aa)
FOXP2Forkhead box protein P2; Transcriptional repressor that may play a role in the specification and differentiation of lung epithelium. May also play a role in developing neural, gastrointestinal and cardiovascular tissues. Can act with CTBP1 to synergistically repress transcription but CTPBP1 is not essential. Plays a role in synapse formation by regulating SRPX2 levels (By similarity). (739 aa)
MRGPRDMAS related GPR family member D; Belongs to the G-protein coupled receptor 1 family. (320 aa)
SCN10ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1956 aa)
SCN7ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1977 aa)
JAK1Tyrosine-protein kinase. (1154 aa)
SCN11ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1790 aa)
TRPC3Transient receptor potential cation channel subfamily C member 3; Belongs to the transient receptor (TC 1.A.4) family. (921 aa)
TRPV1Transient receptor potential cation channel subfamily V member 1; Belongs to the transient receptor (TC 1.A.4) family. (839 aa)
IL31RAInterleukin 31 receptor A. (765 aa)
NTRK3Tyrosine-protein kinase receptor. (850 aa)
APOEApolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...] (317 aa)
TRPM8Transient receptor potential cation channel subfamily M member 8. (1104 aa)
TRPA1Transient receptor potential cation channel subfamily A member 1; Belongs to the transient receptor (TC 1.A.4) family. (1144 aa)
S1PR3Sphingosine 1-phosphate receptor 3; Belongs to the G-protein coupled receptor 1 family. (378 aa)
SCN1ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2008 aa)
ETV1ETS domain-containing protein. (491 aa)
SNAP25Synaptosomal-associated protein 25; t-SNARE involved in the molecular regulation of neurotransmitter release. May play an important role in the synaptic function of specific neuronal systems. Associates with proteins involved in vesicle docking and membrane fusion. Regulates plasma membrane recycling through its interaction with CENPF. Modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1 in pancreatic beta cells. Belongs to the SNAP-25 family. (206 aa)
SCN1BSodium voltage-gated channel beta subunit 1. (402 aa)
NEFHNeurofilament heavy; Belongs to the intermediate filament family. (1017 aa)
IL31Uncharacterized protein. (238 aa)
PVALBParvalbumin; Belongs to the parvalbumin family. (178 aa)
SDF4Stromal cell derived factor 4. (484 aa)
GPR26G-protein coupled receptor 26. (337 aa)
MRGPRX1G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (322 aa)
ADCYAP1Adenylate cyclase activating polypeptide 1. (198 aa)
PIEZO2Piezo-type mechanosensitive ion channel component. (2753 aa)
TMEM100Transmembrane protein 100. (134 aa)
OSMROncostatin M receptor. (977 aa)
NTRK2Tyrosine-protein kinase receptor. (838 aa)
NPPBNatriuretic peptide B. (160 aa)
QKIKH domain-containing protein. (333 aa)
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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